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Published in: European Journal of Trauma and Emergency Surgery 2/2014

01-04-2014 | Review Article

Planned re-laparotomy and the need for optimization of physiology and immunology

Authors: L. Kobayashi, R. Coimbra

Published in: European Journal of Trauma and Emergency Surgery | Issue 2/2014

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Abstract

Planned re-laparotomy or damage control laparotomy (DCL), first described by Dr. Harlan Stone in 1983, has become a widely utilized technique in a broad range of patients and operative situations. Studies have validated the use of DCL by demonstrating decreased mortality and morbidity in trauma, general surgery and abdominal vascular catastrophes. Indications for planned re-laparotomy include severe physiologic derangements, coagulopathy, concern for bowel ischemia, and abdominal compartment syndrome. The immunology of DCL patients is not well described in humans, but promising animal studies suggest a benefit from the open abdomen (OA) and several human trials on this subject are currently underway. Optimal critical care of patients with OA’s, including sedation, paralysis, nutrition, antimicrobial and fluid management strategies have been associated with improved closure rates and recovery.
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Metadata
Title
Planned re-laparotomy and the need for optimization of physiology and immunology
Authors
L. Kobayashi
R. Coimbra
Publication date
01-04-2014
Publisher
Springer Berlin Heidelberg
Published in
European Journal of Trauma and Emergency Surgery / Issue 2/2014
Print ISSN: 1863-9933
Electronic ISSN: 1863-9941
DOI
https://doi.org/10.1007/s00068-014-0396-5

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