Skip to main content
Top
Published in: Strahlentherapie und Onkologie 12/2017

01-12-2017 | Original Article

Automated IMRT planning in Pinnacle

A study in head-and-neck cancer

Authors: J. M. A. M. Kusters, PhD, K. Bzdusek, PhD, P. Kumar, MSc, P. G. M van Kollenburg, RTT, M. C. Kunze-Busch, PhD, M. Wendling, PhD, T. Dijkema, MD, PhD, J. H. A. M. Kaanders, MD, PhD

Published in: Strahlentherapie und Onkologie | Issue 12/2017

Login to get access

Abstract

Purpose

This study evaluates the performance and planning efficacy of the Auto-Planning (AP) module in the clinical version of Pinnacle 9.10 (Philips Radiation Oncology Systems, Fitchburg, WI, USA).

Methods and materials

Twenty automated intensity-modulated radiotherapy (IMRT) plans were compared with the original manually planned clinical IMRT plans from patients with oropharyngeal cancer.

Results

Auto-Planning with IMRT offers similar coverage of the planning target volume as the original manually planned clinical plans, as well as better sparing of the contralateral parotid gland, contralateral submandibular gland, larynx, mandible, and brainstem. The mean dose of the contralateral parotid gland and contralateral submandibular gland could be reduced by 2.5 Gy and 1.7 Gy on average. The number of monitor units was reduced with an average of 143.9 (18%). Hands-on planning time was reduced from 1.5–3 h to less than 1 h.

Conclusions

The Auto-Planning module was able to produce clinically acceptable head and neck IMRT plans with consistent quality.
Literature
1.
go back to reference Nelms BE, Robinson G, Markham J, Velasco K, Boyd S, Narayan S, Wheeler J, Sobczak ML (2012) Variation in external beam treatment plan quality: an inter-institutional study of planners and planning systems. Pract Radiat Oncol 2(4):296–305CrossRefPubMed Nelms BE, Robinson G, Markham J, Velasco K, Boyd S, Narayan S, Wheeler J, Sobczak ML (2012) Variation in external beam treatment plan quality: an inter-institutional study of planners and planning systems. Pract Radiat Oncol 2(4):296–305CrossRefPubMed
2.
go back to reference Xhaferllari I, Wong E, Bzdusek K, Lock M, Chen JZ (2013) Automated IMRT planning with regional optimization using planning scripts. J Appl Clin Med Phys 14(1):4052CrossRefPubMed Xhaferllari I, Wong E, Bzdusek K, Lock M, Chen JZ (2013) Automated IMRT planning with regional optimization using planning scripts. J Appl Clin Med Phys 14(1):4052CrossRefPubMed
3.
go back to reference Wilkens JJ, Alaly JR, Zakarian K, Thorstad WL, Deasy JO (2007) IMRT treatment planning based on prioritizing prescription goals. Phys Med Biol 52(6):1675–1692CrossRefPubMed Wilkens JJ, Alaly JR, Zakarian K, Thorstad WL, Deasy JO (2007) IMRT treatment planning based on prioritizing prescription goals. Phys Med Biol 52(6):1675–1692CrossRefPubMed
4.
go back to reference Voet PW, Dirk ML, Breedveld S, Al-Mamgani A, Incrocci L, Heijmen BJ (2014) Fully automated volumetric modulated arc therapy plan generation for prostate cancer patients. Int J Radiat Oncol Biol Phys 88(5):1175–1179CrossRefPubMed Voet PW, Dirk ML, Breedveld S, Al-Mamgani A, Incrocci L, Heijmen BJ (2014) Fully automated volumetric modulated arc therapy plan generation for prostate cancer patients. Int J Radiat Oncol Biol Phys 88(5):1175–1179CrossRefPubMed
5.
go back to reference Li X, Quan EM, Pan X, Li Y (2011) A methodology for automatic intensity-modulated radiation treatment planning for lung cancer. Phys Med Biol 56(13):3873–3893CrossRefPubMed Li X, Quan EM, Pan X, Li Y (2011) A methodology for automatic intensity-modulated radiation treatment planning for lung cancer. Phys Med Biol 56(13):3873–3893CrossRefPubMed
6.
go back to reference Breedveld S, Storchi PRM, Keijzer M, Heemink AW, Heijmen BJM (2007) A novel approach to multi-criteria inverse planning for IMRT. Phys Med Biol 52:6339CrossRefPubMed Breedveld S, Storchi PRM, Keijzer M, Heemink AW, Heijmen BJM (2007) A novel approach to multi-criteria inverse planning for IMRT. Phys Med Biol 52:6339CrossRefPubMed
8.
go back to reference Wu B, McNutt T, Zahurak M, Simari P, Pang D, Taylor R, Sanguineti G (2012) Fully automated simultaneous integrated boosted intensity modulated radiation therapy treatment planning is feasible for head-and-neck cancer: a prospective clinical study. Int J Radiat Oncol Biol Phys 84(5):647–653CrossRef Wu B, McNutt T, Zahurak M, Simari P, Pang D, Taylor R, Sanguineti G (2012) Fully automated simultaneous integrated boosted intensity modulated radiation therapy treatment planning is feasible for head-and-neck cancer: a prospective clinical study. Int J Radiat Oncol Biol Phys 84(5):647–653CrossRef
9.
go back to reference Troost EG, Bussink J, Hoffmann AL, Boerman OC, Oyen WJ, Kaanders JH (2010) 18 F-FLT PET/CT for early response monitoring and dose escalation in oropharyngeal tumors. J Nucl Med 51(6):866–874CrossRefPubMed Troost EG, Bussink J, Hoffmann AL, Boerman OC, Oyen WJ, Kaanders JH (2010) 18 F-FLT PET/CT for early response monitoring and dose escalation in oropharyngeal tumors. J Nucl Med 51(6):866–874CrossRefPubMed
10.
go back to reference Kunze-Buch MC, van Kollenburg P (2007) Efficient SIB-IMRT planning of head and neck patients with Pinnacle3-DMPO. Medicamundi 51(2):95–99 Kunze-Buch MC, van Kollenburg P (2007) Efficient SIB-IMRT planning of head and neck patients with Pinnacle3-DMPO. Medicamundi 51(2):95–99
12.
go back to reference Hazell I, Bzdusek K, Kumar P et al (2016) Automatic planning of head and neck treatment plans. J Appl Clin Med Phys 17:272–282CrossRefPubMed Hazell I, Bzdusek K, Kumar P et al (2016) Automatic planning of head and neck treatment plans. J Appl Clin Med Phys 17:272–282CrossRefPubMed
13.
go back to reference Cotrutz C, Xing L (2003) IMRT dose shaping with regionally variable penalty scheme. Med Phys 30(4):544–551CrossRefPubMed Cotrutz C, Xing L (2003) IMRT dose shaping with regionally variable penalty scheme. Med Phys 30(4):544–551CrossRefPubMed
14.
go back to reference ICRU report 83 (2010) Prescribing, recording, and reporting photon-beam intensity-modulated radiation therapy (IMRT). J ICRU 10:35–36 ICRU report 83 (2010) Prescribing, recording, and reporting photon-beam intensity-modulated radiation therapy (IMRT). J ICRU 10:35–36
15.
go back to reference Paddick I (2000) A simple scoring ratio to index the conformity of radiosurgical treatment plans. J Neurosurg 93:219–222PubMed Paddick I (2000) A simple scoring ratio to index the conformity of radiosurgical treatment plans. J Neurosurg 93:219–222PubMed
16.
go back to reference van’t Riet A, Mak AC, Moerland MA et al (1997) A conformation number to quantify the degree of conformality in brachytherapy and external beam irradiation: application to the prostate. Int J Radiat Oncol Biol Phys 37:731–736CrossRef van’t Riet A, Mak AC, Moerland MA et al (1997) A conformation number to quantify the degree of conformality in brachytherapy and external beam irradiation: application to the prostate. Int J Radiat Oncol Biol Phys 37:731–736CrossRef
18.
go back to reference Kierkels RGJ, Visser R, Bijl HP, Langendijk JA, van ’t Veld AA, Steenbakkers RJHM, Korevaar EW (2015) Multicriteria optimization enables less experienced planners to efficiently produce high quality treatment plans in head and neck cancer radiotherapy. Radiat Oncol 10:87. doi:10.1186/s13014-015-0385-9 CrossRefPubMedPubMedCentral Kierkels RGJ, Visser R, Bijl HP, Langendijk JA, van ’t Veld AA, Steenbakkers RJHM, Korevaar EW (2015) Multicriteria optimization enables less experienced planners to efficiently produce high quality treatment plans in head and neck cancer radiotherapy. Radiat Oncol 10:87. doi:10.​1186/​s13014-015-0385-9 CrossRefPubMedPubMedCentral
19.
go back to reference Tol JP, Dahele M, Delany AR, Slotman BJ, Verbakel WFAR (2015) Can knowledge-based DVH predictions be used for automated, individualized quality assurance of radiotherapy treatment plans? Radiat Oncol 10:234CrossRefPubMedPubMedCentral Tol JP, Dahele M, Delany AR, Slotman BJ, Verbakel WFAR (2015) Can knowledge-based DVH predictions be used for automated, individualized quality assurance of radiotherapy treatment plans? Radiat Oncol 10:234CrossRefPubMedPubMedCentral
21.
go back to reference Dai X, Zhao Y, Liang Z et al (2015) Volumetric-modulated arc therapy for oropharyngeal carcinoma: a dosimetric and delivery efficiency comparison with static-field IMRT. Phys Med 31(1):54–59CrossRefPubMed Dai X, Zhao Y, Liang Z et al (2015) Volumetric-modulated arc therapy for oropharyngeal carcinoma: a dosimetric and delivery efficiency comparison with static-field IMRT. Phys Med 31(1):54–59CrossRefPubMed
Metadata
Title
Automated IMRT planning in Pinnacle
A study in head-and-neck cancer
Authors
J. M. A. M. Kusters, PhD
K. Bzdusek, PhD
P. Kumar, MSc
P. G. M van Kollenburg, RTT
M. C. Kunze-Busch, PhD
M. Wendling, PhD
T. Dijkema, MD, PhD
J. H. A. M. Kaanders, MD, PhD
Publication date
01-12-2017
Publisher
Springer Berlin Heidelberg
Published in
Strahlentherapie und Onkologie / Issue 12/2017
Print ISSN: 0179-7158
Electronic ISSN: 1439-099X
DOI
https://doi.org/10.1007/s00066-017-1187-9

Other articles of this Issue 12/2017

Strahlentherapie und Onkologie 12/2017 Go to the issue