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Published in: Journal of Orofacial Orthopedics / Fortschritte der Kieferorthopädie 2/2018

01-03-2018 | Original Article

Does orthodontic treatment have a permanent effect on tooth color?

A systematic review and meta-analysis

Authors: Rita Kamber, Spyridon N. Papageorgiou, Theodore Eliades

Published in: Journal of Orofacial Orthopedics / Fortschritte der Kieferorthopädie | Issue 2/2018

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Abstract

Objectives

Aim of this systematic review was to assess the effect of orthodontic treatment with fixed appliances on the tooth color of patients.

Methods

Nine databases were searched up to May 2017 for clinical cohort studies on the effect of fixed appliance treatment on tooth color. After elimination of duplicate studies, data extraction, and risk of bias assessment according to the Cochrane guidelines, random effects meta-analyses of mean differences (MD) or means and their 95% confidence intervals (CIs) were performed, followed by GRADE (Grading of Recommendations Assessment, Development and Evaluation) assessment of the quality of evidence.

Results

Three nonrandomized and one randomized study with a total of 138 patients (46% male, 54% female) with average age of 15.7 years were included. Tooth color of treated patients was significantly altered during or after orthodontic treatment (4 studies; average of 3.2 ∆E units; 95% CI = 2.0–4.4 ∆E units), which was more than the variation among controls (1 study; MD = 1.9 ∆E units; 95% CI = 1.7–2.2 ∆E units). However, the quality of evidence was very low, due to the inclusion of nonrandomized studies, bias, and imprecision. Re-analysis of raw study data indicated that significant differences in clinically discernable treatment-induced color changes were seen between chemically and light-cured adhesives and among the various tooth categories.

Conclusion

Existing evidence of very low quality indicates that orthodontic treatment might be associated with alterations of tooth color, which are however not consistently clinically discernible. Treatment-induced color alterations might be dependent on bonding material and tooth type, but evidence supporting this is weak.
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Literature
1.
go back to reference Al Maaitah EF, Omar AAA, Al-Khateeb SN (2013) Effect of fixed orthodontic appliances bonded with different etching techniques on tooth color: a prospective clinical study. Am J Orthod Dentofacial Orthop 144:43–49 Al Maaitah EF, Omar AAA, Al-Khateeb SN (2013) Effect of fixed orthodontic appliances bonded with different etching techniques on tooth color: a prospective clinical study. Am J Orthod Dentofacial Orthop 144:43–49
2.
go back to reference Al Shamsi AH, Cunningham JL, Lamey PJ, Lynch E (2007) Three-dimensional measurement of residual adhesive and enamel loss on teeth after debonding of orthodontic brackets: an in-vitro study. Am J Orthod Dentofacial Orthop 131(301):e9–e15 Al Shamsi AH, Cunningham JL, Lamey PJ, Lynch E (2007) Three-dimensional measurement of residual adhesive and enamel loss on teeth after debonding of orthodontic brackets: an in-vitro study. Am J Orthod Dentofacial Orthop 131(301):e9–e15
3.
go back to reference Arnold S, Koletsi D, Patcas R, Eliades T (2016) The effect of bracket ligation on the periodontal status of adolescents undergoing orthodontic treatment. A systematic review and meta-analysis. J Dent 54:13–24 Arnold S, Koletsi D, Patcas R, Eliades T (2016) The effect of bracket ligation on the periodontal status of adolescents undergoing orthodontic treatment. A systematic review and meta-analysis. J Dent 54:13–24
4.
go back to reference Bollen AM, Cunha-Cruz J, Bakko DW, Huang GJ, Hujoel PP (2008) The effects of orthodontic therapy on periodontal health: a systematic review of controlled evidence. J Am Dent Assoc 139:413–422 Bollen AM, Cunha-Cruz J, Bakko DW, Huang GJ, Hujoel PP (2008) The effects of orthodontic therapy on periodontal health: a systematic review of controlled evidence. J Am Dent Assoc 139:413–422
5.
go back to reference Buonocore MG, Matsui A, Gwinnett AJ (1968) Penetration of resin dental materials into enamel surfaces with reference to bonding. Arch Oral Biol 13:61–70 Buonocore MG, Matsui A, Gwinnett AJ (1968) Penetration of resin dental materials into enamel surfaces with reference to bonding. Arch Oral Biol 13:61–70
6.
go back to reference Chen Q, Zheng X, Chen W, Ni Z, Yu Z (2015) Influence of orthodontic treatment with fixed appliances on enamel color: a systematic review. BMC Oral Health 15:13 Chen Q, Zheng X, Chen W, Ni Z, Yu Z (2015) Influence of orthodontic treatment with fixed appliances on enamel color: a systematic review. BMC Oral Health 15:13
7.
go back to reference Chung K (1994) Effects of finishing and polishing procedures on the surface texture of resin composites. Dent Mater 10:325–330 Chung K (1994) Effects of finishing and polishing procedures on the surface texture of resin composites. Dent Mater 10:325–330
8.
go back to reference Cinader D (2001) Chemical processes and performance comparisons of transbond plus self-etching primer. Orthod Perspect 8:5–6 Cinader D (2001) Chemical processes and performance comparisons of transbond plus self-etching primer. Orthod Perspect 8:5–6
9.
go back to reference Douglas RD (1997) Precision of in vivo colorimetric assessments of teeth. J Prosthet Dent 77:464–470 Douglas RD (1997) Precision of in vivo colorimetric assessments of teeth. J Prosthet Dent 77:464–470
10.
go back to reference Eldiwany M, Friedl KH, Powers JM (1995) Color stability of light-cured and post-cured composites. Am J Dent 8:179–181 Eldiwany M, Friedl KH, Powers JM (1995) Color stability of light-cured and post-cured composites. Am J Dent 8:179–181
11.
go back to reference Eliades T, Athanasiou AE (2002) In vivo aging of orthodontic alloys: implications for corrosion potential, nickel release, and biocompatibility. Angle Orthod 72:222–237 Eliades T, Athanasiou AE (2002) In vivo aging of orthodontic alloys: implications for corrosion potential, nickel release, and biocompatibility. Angle Orthod 72:222–237
12.
go back to reference Eliades T, Gioka C, Heim M, Eliades G, Makou M (2004) Color stability of orthodontic adhesive resins. Angle Orthod 74:391–393 Eliades T, Gioka C, Heim M, Eliades G, Makou M (2004) Color stability of orthodontic adhesive resins. Angle Orthod 74:391–393
13.
go back to reference Eliades T, Kakaboura A, Eliades G, Bradley TG (2001) Comparison of enamel colour changes associated with orthodontic bonding using two different adhesives. Eur J Orthod 23:85–90 Eliades T, Kakaboura A, Eliades G, Bradley TG (2001) Comparison of enamel colour changes associated with orthodontic bonding using two different adhesives. Eur J Orthod 23:85–90
14.
go back to reference Gioka C, Bourauel C, Hiskia A, Kletsas D, Eliades T, Eliades G (2005) Light-cured or chemically cured orthodontic adhesive resins? A selection based on the degree of cure, monomer leaching, and cytotoxicity. Am J Orthod Dentofacial Orthop 127:413–419 Gioka C, Bourauel C, Hiskia A, Kletsas D, Eliades T, Eliades G (2005) Light-cured or chemically cured orthodontic adhesive resins? A selection based on the degree of cure, monomer leaching, and cytotoxicity. Am J Orthod Dentofacial Orthop 127:413–419
15.
go back to reference Gorelick L, Geiger AM, Gwinnett AJ (1982) Incidence of white spot formation after bonding and banding. Am J Orthod 81:93–98 Gorelick L, Geiger AM, Gwinnett AJ (1982) Incidence of white spot formation after bonding and banding. Am J Orthod 81:93–98
16.
go back to reference Guyatt GH, Oxman AD, Schünemann HJ, Tugwell P, Knottnerus A (2011) GRADE guidelines: a new series of articles in the Journal of Clinical Epidemiology. J Clin Epidemiol 64:380–382 Guyatt GH, Oxman AD, Schünemann HJ, Tugwell P, Knottnerus A (2011) GRADE guidelines: a new series of articles in the Journal of Clinical Epidemiology. J Clin Epidemiol 64:380–382
17.
go back to reference Higgins JP, Thompson SG, Deeks JJ, Altman DG (2003) Measuring inconsistency in meta-analyses. BMJ 327:557–560 Higgins JP, Thompson SG, Deeks JJ, Altman DG (2003) Measuring inconsistency in meta-analyses. BMJ 327:557–560
18.
go back to reference Higgins JP, Thompson SG, Spiegelhalter DJ (2009) A re-evaluation of random-effects meta-analysis. J R Stat Soc Ser A Stat Soc 172:137–159 Higgins JP, Thompson SG, Spiegelhalter DJ (2009) A re-evaluation of random-effects meta-analysis. J R Stat Soc Ser A Stat Soc 172:137–159
20.
go back to reference Hodges SJ, Spencer RJ, Watkins SJ (2000) Unusual indelible enamel staining following fixed appliance treatment. J Orthod 27:303–306 Hodges SJ, Spencer RJ, Watkins SJ (2000) Unusual indelible enamel staining following fixed appliance treatment. J Orthod 27:303–306
21.
go back to reference Inokoshi S, Burrow MF, Kataumi M, Yamada T, Takatsu T (1996) Opacity and color changes of tooth-colored restorative materials. Oper Dent 21:73–80 Inokoshi S, Burrow MF, Kataumi M, Yamada T, Takatsu T (1996) Opacity and color changes of tooth-colored restorative materials. Oper Dent 21:73–80
22.
go back to reference Johnston WM, Kao EC (1989) Assessment of appearance match by visual observation and clinical colorimetry. J Dent Res 68:819–822 Johnston WM, Kao EC (1989) Assessment of appearance match by visual observation and clinical colorimetry. J Dent Res 68:819–822
23.
go back to reference Joiner A, Hopkinson I, Deng Y, Westland S (2008) A review of tooth colour and whiteness. J Dent 36(Suppl 1):S2–S7 Joiner A, Hopkinson I, Deng Y, Westland S (2008) A review of tooth colour and whiteness. J Dent 36(Suppl 1):S2–S7
24.
go back to reference Joss-Vassalli I, Grebenstein C, Topouzelis N, Sculean A, Katsaros C (2010) Orthodontic therapy and gingival recession: a systematic review. Orthod Craniofac Res 13:127–141 Joss-Vassalli I, Grebenstein C, Topouzelis N, Sculean A, Katsaros C (2010) Orthodontic therapy and gingival recession: a systematic review. Orthod Craniofac Res 13:127–141
25.
go back to reference Karamouzos A, Athanasiou AE, Papadopoulos MA, Kolkithas G (2010) Tooth color assessment after orthodontic treatment: a prospective clinical trial. Am J Orthod Dentofacial Orthop 138(537):e1–e8 Karamouzos A, Athanasiou AE, Papadopoulos MA, Kolkithas G (2010) Tooth color assessment after orthodontic treatment: a prospective clinical trial. Am J Orthod Dentofacial Orthop 138(537):e1–e8
26.
go back to reference Kershaw S, Newton JT, Williams DM (2008) The influence of tooth colour on the perceptions of personal characteristics among female dental patients: comparisons of unmodified, decayed and “whitened” teeth. Br Dent J 204:E9 Kershaw S, Newton JT, Williams DM (2008) The influence of tooth colour on the perceptions of personal characteristics among female dental patients: comparisons of unmodified, decayed and “whitened” teeth. Br Dent J 204:E9
27.
go back to reference Kim SP, Hwang IN, Cho JH, Hwang HS (2006) Tooth color changes associated with the bracket bonding and debonding. Korean J Orthod 36:114–124 Kim SP, Hwang IN, Cho JH, Hwang HS (2006) Tooth color changes associated with the bracket bonding and debonding. Korean J Orthod 36:114–124
28.
go back to reference Liberati A, Altman DG, Tetzlaff J, Mulrow C, Gøtzsche PC, Ioannidis JP, Clarke M, Devereaux PJ, Kleijnen J, Moher D (2009) The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. J Clin Epidemiol 62:e1–e34 Liberati A, Altman DG, Tetzlaff J, Mulrow C, Gøtzsche PC, Ioannidis JP, Clarke M, Devereaux PJ, Kleijnen J, Moher D (2009) The PRISMA statement for reporting systematic reviews and meta-analyses of studies that evaluate health care interventions: explanation and elaboration. J Clin Epidemiol 62:e1–e34
30.
go back to reference Nathoo SA (1997) The chemistry and mechanisms of extrinsic and intrinsic discoloration. J Am Dent Assoc 128(Suppl):6S–10S Nathoo SA (1997) The chemistry and mechanisms of extrinsic and intrinsic discoloration. J Am Dent Assoc 128(Suppl):6S–10S
31.
go back to reference Øgaard B, Rolla G, Arends J (1988) Orthodontic appliances and enamel demineralization. Part 1. Lesion development. Am J Orthod Dentofacial Orthop 94:68–73 Øgaard B, Rolla G, Arends J (1988) Orthodontic appliances and enamel demineralization. Part 1. Lesion development. Am J Orthod Dentofacial Orthop 94:68–73
32.
go back to reference Papageorgiou SN (2014) Meta-analysis for orthodontists: part II—is all that glitters gold? J Orthod 41:327–336 Papageorgiou SN (2014) Meta-analysis for orthodontists: part II—is all that glitters gold? J Orthod 41:327–336
33.
go back to reference Papageorgiou SN, Höchli D, Eliades T (2017) Outcomes of comprehensive fixed appliance orthodontic treatment: a systematic review with meta-analysis and methodological overview. Korean J Orthod 47:401–413 Papageorgiou SN, Höchli D, Eliades T (2017) Outcomes of comprehensive fixed appliance orthodontic treatment: a systematic review with meta-analysis and methodological overview. Korean J Orthod 47:401–413
35.
go back to reference Papageorgiou SN, Xavier GM, Cobourne MT (2015) Basic study design influences the results of orthodontic clinical investigations. J Clin Epidemiol 68:1512–1522 Papageorgiou SN, Xavier GM, Cobourne MT (2015) Basic study design influences the results of orthodontic clinical investigations. J Clin Epidemiol 68:1512–1522
36.
go back to reference Retief DH, Busscher HJ, de Boer P, Jongebloed WL, Arends J (1986) A laboratory evaluation of three etching solutions. Dent Mater 2:202–206 Retief DH, Busscher HJ, de Boer P, Jongebloed WL, Arends J (1986) A laboratory evaluation of three etching solutions. Dent Mater 2:202–206
37.
go back to reference Ribeiro AA, Almeida LF, Martins LP, Martins RP (2017) Assessing adhesive remnant removal and enamel damage with ultraviolet light: an in-vitro study. Am J Orthod Dentofacial Orthop 151:292–296 Ribeiro AA, Almeida LF, Martins LP, Martins RP (2017) Assessing adhesive remnant removal and enamel damage with ultraviolet light: an in-vitro study. Am J Orthod Dentofacial Orthop 151:292–296
38.
go back to reference Russell MD, Gulfraz M, Moss BW (2000) In-vivo measurement of colour changes in natural teeth. J Oral Rehabil 27:786–792 Russell MD, Gulfraz M, Moss BW (2000) In-vivo measurement of colour changes in natural teeth. J Oral Rehabil 27:786–792
39.
go back to reference Sandison RM (1981) Tooth surface appearance after debonding. Br J Orthod 8:199–201 Sandison RM (1981) Tooth surface appearance after debonding. Br J Orthod 8:199–201
40.
go back to reference Shamseer L, Moher D, Clarke M, Ghersi D, Liberati A, Petticrew M, Shekelle P, Stewart LA, P Group (2015) Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols (PRISMA-P) 2015: elaboration and explanation. BMJ 349:g7647 Shamseer L, Moher D, Clarke M, Ghersi D, Liberati A, Petticrew M, Shekelle P, Stewart LA, P Group (2015) Preferred Reporting Items for Systematic Review and Meta-Analysis Protocols (PRISMA-P) 2015: elaboration and explanation. BMJ 349:g7647
41.
go back to reference Shojania KG, Sampson M, Ansari MT, Ji J, Doucette S, Moher D (2007) How quickly do systematic reviews go out of date? A survival analysis. Ann Intern Med 147:224–233 Shojania KG, Sampson M, Ansari MT, Ji J, Doucette S, Moher D (2007) How quickly do systematic reviews go out of date? A survival analysis. Ann Intern Med 147:224–233
42.
go back to reference Sideri S, Papageorgiou SN, Eliades T (2017) Are orthodontic systematic reviews registered a priori in PROSPERO? J Orthod 7:1–7 Sideri S, Papageorgiou SN, Eliades T (2017) Are orthodontic systematic reviews registered a priori in PROSPERO? J Orthod 7:1–7
43.
go back to reference Sifakakis I, Eliades T (2017) Adverse reactions to orthodontic materials. Aust Dent J 62(Suppl 1):20–28 Sifakakis I, Eliades T (2017) Adverse reactions to orthodontic materials. Aust Dent J 62(Suppl 1):20–28
44.
go back to reference Sterne JA, Hernán MA, Reeves BC, Savović J, Berkman ND, Viswanathan M, Henry D, Altman DG, Ansari MT, Boutron I, Carpenter JR, Chan AW, Churchill R, Deeks JJ, Hróbjartsson A, Kirkham J, Jüni P, Loke YK, Pigott TD, Ramsay CR, Regidor D, Rothstein HR, Sandhu L, Santaguida PL, Schünemann HJ, Shea B, Shrier I, Tugwell P, Turner L, Valentine JC, Waddington H, Waters E, Wells GA, Whiting PF, Higgins JP (2016) ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions. BMJ 355:i4919 Sterne JA, Hernán MA, Reeves BC, Savović J, Berkman ND, Viswanathan M, Henry D, Altman DG, Ansari MT, Boutron I, Carpenter JR, Chan AW, Churchill R, Deeks JJ, Hróbjartsson A, Kirkham J, Jüni P, Loke YK, Pigott TD, Ramsay CR, Regidor D, Rothstein HR, Sandhu L, Santaguida PL, Schünemann HJ, Shea B, Shrier I, Tugwell P, Turner L, Valentine JC, Waddington H, Waters E, Wells GA, Whiting PF, Higgins JP (2016) ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions. BMJ 355:i4919
45.
go back to reference ten Bosch JJ, Coops JC (1995) Tooth color and reflectance as related to light scattering and enamel hardness. J Dent Res 74:374–380 ten Bosch JJ, Coops JC (1995) Tooth color and reflectance as related to light scattering and enamel hardness. J Dent Res 74:374–380
46.
go back to reference Tong LS, Pang MK, Mok NY, King NM, Wei SH (1993) The effects of etching, micro-abrasion, and bleaching on surface enamel. J Dent Res 72:67–71 Tong LS, Pang MK, Mok NY, King NM, Wei SH (1993) The effects of etching, micro-abrasion, and bleaching on surface enamel. J Dent Res 72:67–71
47.
go back to reference Veroniki AA, Jackson D, Viechtbauer W, Bender R, Bowden J, Knapp G, Kuss O, Higgins JP, Langan D, Salanti G (2016) Methods to estimate the between-study variance and its uncertainty in meta-analysis. Res Synth Methods 7:55–79 Veroniki AA, Jackson D, Viechtbauer W, Bender R, Bowden J, Knapp G, Kuss O, Higgins JP, Langan D, Salanti G (2016) Methods to estimate the between-study variance and its uncertainty in meta-analysis. Res Synth Methods 7:55–79
48.
go back to reference Watts A, Addy M (2001) Tooth discolouration and staining: a review of the literature. Br Dent J 190:309–316 Watts A, Addy M (2001) Tooth discolouration and staining: a review of the literature. Br Dent J 190:309–316
49.
go back to reference Weltman B, Vig KW, Fields HW, Shanker S, Kaizar EE (2010) Root resorption associated with orthodontic tooth movement: a systematic review. Am J Orthod Dentofacial Orthop 137:462–476 Weltman B, Vig KW, Fields HW, Shanker S, Kaizar EE (2010) Root resorption associated with orthodontic tooth movement: a systematic review. Am J Orthod Dentofacial Orthop 137:462–476
50.
go back to reference Zachrisson BJ (1977) A posttreatment evaluation of direct bonding in orthodontics. Am J Orthod 71:173–189 Zachrisson BJ (1977) A posttreatment evaluation of direct bonding in orthodontics. Am J Orthod 71:173–189
51.
go back to reference Zarrinnia K, Eid NM, Kehoe MJ (1995) The effect of different debonding techniques on the enamel surface: an in vitro qualitative study. Am J Orthod Dentofacial Orthop 108:284–293 Zarrinnia K, Eid NM, Kehoe MJ (1995) The effect of different debonding techniques on the enamel surface: an in vitro qualitative study. Am J Orthod Dentofacial Orthop 108:284–293
Metadata
Title
Does orthodontic treatment have a permanent effect on tooth color?
A systematic review and meta-analysis
Authors
Rita Kamber
Spyridon N. Papageorgiou
Theodore Eliades
Publication date
01-03-2018
Publisher
Springer Medizin
Published in
Journal of Orofacial Orthopedics / Fortschritte der Kieferorthopädie / Issue 2/2018
Print ISSN: 1434-5293
Electronic ISSN: 1615-6714
DOI
https://doi.org/10.1007/s00056-018-0123-7

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