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Published in: International Journal of Public Health 3/2010

01-06-2010 | Original Article

Alcohol consumption and risk of incident human immunodeficiency virus infection: a meta-analysis

Authors: Dolly Baliunas, Jürgen Rehm, Hyacinth Irving, Paul Shuper

Published in: International Journal of Public Health | Issue 3/2010

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Abstract

Objective

To analyze the relationship between alcohol consumption and incident HIV infection.

Methods

Articles were identified via electronic and hand searches. Inclusion criteria were: incident HIV infection, preceding alcohol consumption, and association relating the two. The DerSimonian and Laird random effects model was used. For studies with more than one estimate of a given type, estimates were combined using the inverse variance weighted method. Publication bias was assessed using Begg’s and Egger’s tests. Heterogeneity was assessed using Q and I 2 statistics.

Results

Ten studies were included. Overall alcohol consumption (any of the three types identified) increased the risk of HIV (RR 1.98, 95% CI 1.59–2.47). Alcohol consumers were at 77% higher risk (RR 1.77, 95% CI 1.43–2.19). Those consuming alcohol prior to, or at the time of, sexual relations were at an 87% increased risk (RR 1.87, 95% CI 1.39–2.50). For binge drinkers, the risk was double that of non-binge drinkers (RR 2.20, 95% CI 1.29–3.74).

Conclusions

Alcohol consumption is associated with an increased risk of incident HIV infection. Additional research is required to further investigate a possible causal role.
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Metadata
Title
Alcohol consumption and risk of incident human immunodeficiency virus infection: a meta-analysis
Authors
Dolly Baliunas
Jürgen Rehm
Hyacinth Irving
Paul Shuper
Publication date
01-06-2010
Publisher
SP Birkhäuser Verlag Basel
Published in
International Journal of Public Health / Issue 3/2010
Print ISSN: 1661-8556
Electronic ISSN: 1661-8564
DOI
https://doi.org/10.1007/s00038-009-0095-x

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