Skip to main content
Top
Published in: Current Addiction Reports 3/2015

01-09-2015 | Gambling (L Clark, Section Editor)

Executive Functioning in Gambling Disorder: Cognitive Profiles and Associations with Clinical Outcomes

Authors: Antonio Verdejo-Garcia, Victoria Manning

Published in: Current Addiction Reports | Issue 3/2015

Login to get access

Abstract

Gambling disorder shares neurobiological and clinical symptoms with substance use disorders; however, it remains unclear if they share executive functioning deficits that compromise gambling treatments. In this review article, findings from the resurgence in clinical and cognitive neuroscience studies in the past 3 years are considered and their role in clinical decision-making re-appraised. In contrast to early findings, novel studies are suggestive of preserved general executive functions (i.e. working memory, planning, rule shifting), but lend further support for deficits of response inhibition, reward-related switching and value-based decision-making, although evidence of their impact on treatment outcome remains limited. The hallmark characteristic of disordered gambling “cognitive impulsivity” may reflect an underlying core alteration in value coding. Increased attention to wins and blunted attention to losses may serve to maintain maladaptive gambling behaviours (e.g. loss chasing), thus the effectiveness of interventions targeting faulty brain value systems (e.g. cognitive bias modification) warrants investigation with this population.
Literature
1.
go back to reference American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 5th ed. Arlington: American Psychiatric Publishing; 2013.CrossRef American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 5th ed. Arlington: American Psychiatric Publishing; 2013.CrossRef
2.
go back to reference Fernandez-Serrano MJ, Perez-Garcia M, Verdejo-Garcia A. What are the specific vs. generalized effects of drugs of abuse on neuropsychological performance? Neurosci Biobehav Rev. 2011;35(3):377–406.PubMedCrossRef Fernandez-Serrano MJ, Perez-Garcia M, Verdejo-Garcia A. What are the specific vs. generalized effects of drugs of abuse on neuropsychological performance? Neurosci Biobehav Rev. 2011;35(3):377–406.PubMedCrossRef
3.
go back to reference Stevens L, Goudriaan AE, Verdejo-Garcia A, Dom G, Roeyers H, Vanderplasschen W. Impulsive choice predicts short-term relapse in substance-dependent individuals attending an in-patient detoxification programme. Psychol Med. 2015;2:1–11. Stevens L, Goudriaan AE, Verdejo-Garcia A, Dom G, Roeyers H, Vanderplasschen W. Impulsive choice predicts short-term relapse in substance-dependent individuals attending an in-patient detoxification programme. Psychol Med. 2015;2:1–11.
4.
go back to reference Streeter CC, Terhune DB, Whitfield TH, Gruber S, Sarid-Segal O, Silveri MM, et al. Performance on the Stroop predicts treatment compliance in cocaine-dependent individuals. Neuropsychopharmacol Off Publ Am Coll Neuropsychopharmacol. 2008;33(4):827–36.CrossRef Streeter CC, Terhune DB, Whitfield TH, Gruber S, Sarid-Segal O, Silveri MM, et al. Performance on the Stroop predicts treatment compliance in cocaine-dependent individuals. Neuropsychopharmacol Off Publ Am Coll Neuropsychopharmacol. 2008;33(4):827–36.CrossRef
5.
go back to reference Verdejo-Garcia A, Albein-Urios N, Martinez-Gonzalez JM, Civit E, de la Torre R, Lozano O. Decision-making impairment predicts 3-month hair-indexed cocaine relapse. Psychopharmacology. 2014;231(21):4179–87.PubMedCrossRef Verdejo-Garcia A, Albein-Urios N, Martinez-Gonzalez JM, Civit E, de la Torre R, Lozano O. Decision-making impairment predicts 3-month hair-indexed cocaine relapse. Psychopharmacology. 2014;231(21):4179–87.PubMedCrossRef
6.
go back to reference Stevens L, Verdejo-Garcia A, Goudriaan AE, Roeyers H, Dom G, Vanderplasschen W. Impulsivity as a vulnerability factor for poor addiction treatment outcomes: a review of neurocognitive findings among individuals with substance use disorders. J Subst Abus Treat. 2014;47(1):58–72.CrossRef Stevens L, Verdejo-Garcia A, Goudriaan AE, Roeyers H, Dom G, Vanderplasschen W. Impulsivity as a vulnerability factor for poor addiction treatment outcomes: a review of neurocognitive findings among individuals with substance use disorders. J Subst Abus Treat. 2014;47(1):58–72.CrossRef
7.
go back to reference Bates ME, Buckman JF, Nguyen TT. A role for cognitive rehabilitation in increasing the effectiveness of treatment for alcohol use disorders. Neuropsychol Rev. 2013;23(1):27–47.PubMedPubMedCentralCrossRef Bates ME, Buckman JF, Nguyen TT. A role for cognitive rehabilitation in increasing the effectiveness of treatment for alcohol use disorders. Neuropsychol Rev. 2013;23(1):27–47.PubMedPubMedCentralCrossRef
8.
go back to reference Goudriaan AE, Oosterlaan J, de Beurs E, van den Brink W. Decision making in pathological gambling: a comparison between pathological gamblers, alcohol dependents, persons with Tourette syndrome, and normal controls. Brain Res Cogn Brain Res. 2005;23(1):137–51.PubMedCrossRef Goudriaan AE, Oosterlaan J, de Beurs E, van den Brink W. Decision making in pathological gambling: a comparison between pathological gamblers, alcohol dependents, persons with Tourette syndrome, and normal controls. Brain Res Cogn Brain Res. 2005;23(1):137–51.PubMedCrossRef
9.
go back to reference Goudriaan AE, Oosterlaan J, de Beurs E, van den Brink W. Neurocognitive functions in pathological gambling: a comparison with alcohol dependence, Tourette syndrome and normal controls. Addiction. 2006;101(4):534–47.PubMedCrossRef Goudriaan AE, Oosterlaan J, de Beurs E, van den Brink W. Neurocognitive functions in pathological gambling: a comparison with alcohol dependence, Tourette syndrome and normal controls. Addiction. 2006;101(4):534–47.PubMedCrossRef
10.
go back to reference Lawrence AJ, Luty J, Bogdan NA, Sahakian BJ, Clark L. Impulsivity and response inhibition in alcohol dependence and problem gambling. Psychopharmacology. 2009;207(1):163–72.PubMedPubMedCentralCrossRef Lawrence AJ, Luty J, Bogdan NA, Sahakian BJ, Clark L. Impulsivity and response inhibition in alcohol dependence and problem gambling. Psychopharmacology. 2009;207(1):163–72.PubMedPubMedCentralCrossRef
11.
go back to reference de Ruiter MB, Oosterlaan J, Veltman DJ, van den Brink W, Goudriaan AE. Similar hyporesponsiveness of the dorsomedial prefrontal cortex in problem gamblers and heavy smokers during an inhibitory control task. Drug Alcohol Depend. 2012;121(1–2):81–9.PubMedCrossRef de Ruiter MB, Oosterlaan J, Veltman DJ, van den Brink W, Goudriaan AE. Similar hyporesponsiveness of the dorsomedial prefrontal cortex in problem gamblers and heavy smokers during an inhibitory control task. Drug Alcohol Depend. 2012;121(1–2):81–9.PubMedCrossRef
12.
go back to reference Verdejo-Garcia A, Clark L, Verdejo-Roman J, Albein-Urios N, Martinez-Gonzalez JM, Gutierrez B, Soriano-Mas C. Neural substrates of cognitive flexibility in stimulant and gambling addictions. Br J Psychiatry. in press. Verdejo-Garcia A, Clark L, Verdejo-Roman J, Albein-Urios N, Martinez-Gonzalez JM, Gutierrez B, Soriano-Mas C. Neural substrates of cognitive flexibility in stimulant and gambling addictions. Br J Psychiatry. in press.
13.
go back to reference Verdejo-Garcia A, Perez-Garcia M. Profile of executive deficits in cocaine and heroin polysubstance users: common and differential effects on separate executive components. Psychopharmacology. 2007;190(4):517–30.PubMedCrossRef Verdejo-Garcia A, Perez-Garcia M. Profile of executive deficits in cocaine and heroin polysubstance users: common and differential effects on separate executive components. Psychopharmacology. 2007;190(4):517–30.PubMedCrossRef
14.••
go back to reference Albein-Urios N, Martinez-Gonzalez JM, Lozano O, Clark L, Verdejo-Garcia A. Comparison of impulsivity and working memory in cocaine addiction and pathological gambling: Implications for cocaine-induced neurotoxicity. Drug Alcohol Depend. 2012;126(1–2):1–6. Demonstrates that pathological gamblers (PGs) and cocaine dependents have common deficits in response inhibition. Conversely, PGs have normal working memory performance in an n-back task. Illustrates specificity of executive function deficits in gambling disorder.PubMedCrossRef Albein-Urios N, Martinez-Gonzalez JM, Lozano O, Clark L, Verdejo-Garcia A. Comparison of impulsivity and working memory in cocaine addiction and pathological gambling: Implications for cocaine-induced neurotoxicity. Drug Alcohol Depend. 2012;126(1–2):1–6. Demonstrates that pathological gamblers (PGs) and cocaine dependents have common deficits in response inhibition. Conversely, PGs have normal working memory performance in an n-back task. Illustrates specificity of executive function deficits in gambling disorder.PubMedCrossRef
15.
go back to reference Brevers D, Cleeremans A, Goudriaan AE, Bechara A, Kornreich C, Verbanck P, et al. Decision making under ambiguity but not under risk is related to problem gambling severity. Psychiatry Res. 2012;200(2–3):568–74.PubMedCrossRef Brevers D, Cleeremans A, Goudriaan AE, Bechara A, Kornreich C, Verbanck P, et al. Decision making under ambiguity but not under risk is related to problem gambling severity. Psychiatry Res. 2012;200(2–3):568–74.PubMedCrossRef
16.
go back to reference Ledgerwood DM, Orr ES, Kaploun KA, Milosevic A, Frisch GR, Rupcich N, et al. Executive function in pathological gamblers and healthy controls. J Gambl Stud. 2012;28(1):89–103.PubMedCrossRef Ledgerwood DM, Orr ES, Kaploun KA, Milosevic A, Frisch GR, Rupcich N, et al. Executive function in pathological gamblers and healthy controls. J Gambl Stud. 2012;28(1):89–103.PubMedCrossRef
17.
go back to reference Manning V, Teoh HC, Guo S, Wong KE, Li TK. Executive functioning in Asian pathological gamblers. Int Gambl Stud. 2013;13(3):403–16.CrossRef Manning V, Teoh HC, Guo S, Wong KE, Li TK. Executive functioning in Asian pathological gamblers. Int Gambl Stud. 2013;13(3):403–16.CrossRef
18.
go back to reference Yan WS, Li YH, Xiao L, Zhu N, Bechara A, Sui N. Working memory and affective decision-making in addiction: a neurocognitive comparison between heroin addicts, pathological gamblers and healthy controls. Drug Alcohol Depend. 2014;134:194–200.PubMedCrossRef Yan WS, Li YH, Xiao L, Zhu N, Bechara A, Sui N. Working memory and affective decision-making in addiction: a neurocognitive comparison between heroin addicts, pathological gamblers and healthy controls. Drug Alcohol Depend. 2014;134:194–200.PubMedCrossRef
19.••
go back to reference Brevers D, Cleeremans A, Verbruggen F, Bechara A, Kornreich C, Verbanck P, et al. Impulsive action but not impulsive choice determines problem gambling severity. PloS one. 2012;7(11):e50647. Demonstrates that deficits in stop signal response inhibition differentiate pathological gamblers from both problem gamblers and healthy controls.PubMedPubMedCentralCrossRef Brevers D, Cleeremans A, Verbruggen F, Bechara A, Kornreich C, Verbanck P, et al. Impulsive action but not impulsive choice determines problem gambling severity. PloS one. 2012;7(11):e50647. Demonstrates that deficits in stop signal response inhibition differentiate pathological gamblers from both problem gamblers and healthy controls.PubMedPubMedCentralCrossRef
20.
go back to reference Hur JW, Shin N, Kim SN, Jang JH, Choi JS, Shin YC, et al. Do pathological gambling and obsessive-compulsive disorder overlap? a neurocognitive perspective. CNS Spectr. 2012;17(4):207–13.PubMedCrossRef Hur JW, Shin N, Kim SN, Jang JH, Choi JS, Shin YC, et al. Do pathological gambling and obsessive-compulsive disorder overlap? a neurocognitive perspective. CNS Spectr. 2012;17(4):207–13.PubMedCrossRef
21.
go back to reference Boog M, Hoppener P, Wetering BJVD, Goudriaan AE, Boog MC, Franken IH. Cognitive inflexibility in gamblers is primarily present in reward-related decision making. Front Hum Neurosci. 2014;8:569.PubMedPubMedCentralCrossRef Boog M, Hoppener P, Wetering BJVD, Goudriaan AE, Boog MC, Franken IH. Cognitive inflexibility in gamblers is primarily present in reward-related decision making. Front Hum Neurosci. 2014;8:569.PubMedPubMedCentralCrossRef
22.
go back to reference Kraplin A, Dshemuchadse M, Behrendt S, Scherbaum S, Goschke T, Buhringer G. Dysfunctional decision-making in pathological gambling: pattern specificity and the role of impulsivity. Psychiatry Res. 2014;215(3):675–82.PubMedCrossRef Kraplin A, Dshemuchadse M, Behrendt S, Scherbaum S, Goschke T, Buhringer G. Dysfunctional decision-making in pathological gambling: pattern specificity and the role of impulsivity. Psychiatry Res. 2014;215(3):675–82.PubMedCrossRef
23.
go back to reference Ochoa C, Alvarez-Moya EM, Penelo E, Aymami MN, Gomez-Pena M, Fernandez-Aranda F, et al. Decision-making deficits in pathological gambling: the role of executive functions, explicit knowledge and impulsivity in relation to decisions made under ambiguity and risk. Am J Addict. 2013;22(5):492–9.PubMedCrossRef Ochoa C, Alvarez-Moya EM, Penelo E, Aymami MN, Gomez-Pena M, Fernandez-Aranda F, et al. Decision-making deficits in pathological gambling: the role of executive functions, explicit knowledge and impulsivity in relation to decisions made under ambiguity and risk. Am J Addict. 2013;22(5):492–9.PubMedCrossRef
24.
go back to reference Bechara A. Risky business: emotion, decision-making, and addiction. J Gambling Stud Co-sponsored Natl Counc Probl Gambl Inst Stud Gambling Commer Gaming. 2003;19(1):23–51. Bechara A. Risky business: emotion, decision-making, and addiction. J Gambling Stud Co-sponsored Natl Counc Probl Gambl Inst Stud Gambling Commer Gaming. 2003;19(1):23–51.
25.
go back to reference Brevers D, Koritzky G, Bechara A, Noel X. Cognitive processes underlying impaired decision-making under uncertainty in gambling disorder. Addict Behav. 2014;39(10):1533–6.PubMedPubMedCentralCrossRef Brevers D, Koritzky G, Bechara A, Noel X. Cognitive processes underlying impaired decision-making under uncertainty in gambling disorder. Addict Behav. 2014;39(10):1533–6.PubMedPubMedCentralCrossRef
26.••
go back to reference Lorains FK, Dowling NA, Enticott PG, Bradshaw JL, Trueblood JS, Stout JC. Strategic and non-strategic problem gamblers differ on decision-making under risk and ambiguity. Addiction. 2014;109(7):1128–37. Demonstrates that the decision-making deficits of pathological gamblers are underlain by hypersensitivity to gains and hyposensitivity to loss processes.PubMedCrossRef Lorains FK, Dowling NA, Enticott PG, Bradshaw JL, Trueblood JS, Stout JC. Strategic and non-strategic problem gamblers differ on decision-making under risk and ambiguity. Addiction. 2014;109(7):1128–37. Demonstrates that the decision-making deficits of pathological gamblers are underlain by hypersensitivity to gains and hyposensitivity to loss processes.PubMedCrossRef
27.
go back to reference O'Connor DA, Meade B, Carter O, Rossiter S, Hester R. Behavioral sensitivity to reward is reduced for far objects. Psychol Sci. 2014;25(1):271–7.PubMedCrossRef O'Connor DA, Meade B, Carter O, Rossiter S, Hester R. Behavioral sensitivity to reward is reduced for far objects. Psychol Sci. 2014;25(1):271–7.PubMedCrossRef
28.•
go back to reference Stevens T, Brevers D, Chambers CD, Lavric A, McLaren IP, Mertens M, et al. How does response inhibition influence decision making when gambling? J Exp Psychol Appl. 2015;21(1):15–36. Introduces the notion that response inhibition deficits in pathological gamblers (PGs) may be underlain by habituated motivational tendencies: Go responses are linked to reward and Stop responses to punishment, thus PGs find more challenging to control responses cached as rewarding.PubMedPubMedCentralCrossRef Stevens T, Brevers D, Chambers CD, Lavric A, McLaren IP, Mertens M, et al. How does response inhibition influence decision making when gambling? J Exp Psychol Appl. 2015;21(1):15–36. Introduces the notion that response inhibition deficits in pathological gamblers (PGs) may be underlain by habituated motivational tendencies: Go responses are linked to reward and Stop responses to punishment, thus PGs find more challenging to control responses cached as rewarding.PubMedPubMedCentralCrossRef
29.
go back to reference Wiers RW, Eberl C, Rinck M, Becker ES, Lindenmeyer J. Retraining automatic action tendencies changes alcoholic patients' approach bias for alcohol and improves treatment outcome. Psychol Sci. 2011;22(4):490–7.PubMedCrossRef Wiers RW, Eberl C, Rinck M, Becker ES, Lindenmeyer J. Retraining automatic action tendencies changes alcoholic patients' approach bias for alcohol and improves treatment outcome. Psychol Sci. 2011;22(4):490–7.PubMedCrossRef
30.
go back to reference Sescousse G, Barbalat G, Domenech P, Dreher JC. Imbalance in the sensitivity to different types of rewards in pathological gambling. Brain J Neurol. 2013;136(Pt 8):2527–38.CrossRef Sescousse G, Barbalat G, Domenech P, Dreher JC. Imbalance in the sensitivity to different types of rewards in pathological gambling. Brain J Neurol. 2013;136(Pt 8):2527–38.CrossRef
31.
go back to reference Clark L, Lawrence AJ, Astley-Jones F, Gray N. Gambling near-misses enhance motivation to gamble and recruit win-related brain circuitry. Neuron. 2009;61(3):481–90.PubMedPubMedCentralCrossRef Clark L, Lawrence AJ, Astley-Jones F, Gray N. Gambling near-misses enhance motivation to gamble and recruit win-related brain circuitry. Neuron. 2009;61(3):481–90.PubMedPubMedCentralCrossRef
32.
go back to reference van Holst RJ, Chase HW, Clark L. Striatal connectivity changes following gambling wins and near-misses: associations with gambling severity. NeuroImage Clin. 2014;5:232–9.PubMedPubMedCentralCrossRef van Holst RJ, Chase HW, Clark L. Striatal connectivity changes following gambling wins and near-misses: associations with gambling severity. NeuroImage Clin. 2014;5:232–9.PubMedPubMedCentralCrossRef
33.
go back to reference Torres A, Catena A, Candido A, Maldonado A, Megias A, Perales JC. Cocaine dependent individuals and gamblers present different associative learning anomalies in feedback-driven decision making: a behavioral and ERP study. Front Psychol. 2013;4:122.PubMedPubMedCentralCrossRef Torres A, Catena A, Candido A, Maldonado A, Megias A, Perales JC. Cocaine dependent individuals and gamblers present different associative learning anomalies in feedback-driven decision making: a behavioral and ERP study. Front Psychol. 2013;4:122.PubMedPubMedCentralCrossRef
34.
go back to reference Kraplin A, Buhringer G, Oosterlaan J, van den Brink W, Goschke T, Goudriaan AE. Dimensions and disorder specificity of impulsivity in pathological gambling. Addict Behav. 2014;39(11):1646–51.PubMedCrossRef Kraplin A, Buhringer G, Oosterlaan J, van den Brink W, Goschke T, Goudriaan AE. Dimensions and disorder specificity of impulsivity in pathological gambling. Addict Behav. 2014;39(11):1646–51.PubMedCrossRef
35.
go back to reference Zois E, Kortlang N, Vollstadt-Klein S, Lemenager T, Beutel M, Mann K, et al. Decision-making deficits in patients diagnosed with disordered gambling using the Cambridge Gambling task: the effects of substance use disorder comorbidity. Brain Behav. 2014;4(4):484–94.PubMedPubMedCentralCrossRef Zois E, Kortlang N, Vollstadt-Klein S, Lemenager T, Beutel M, Mann K, et al. Decision-making deficits in patients diagnosed with disordered gambling using the Cambridge Gambling task: the effects of substance use disorder comorbidity. Brain Behav. 2014;4(4):484–94.PubMedPubMedCentralCrossRef
36.
go back to reference Albein-Urios N, Martinez-Gonzalez JM, Lozano O, Verdejo-Garcia A. Monetary delay discounting in gambling and cocaine dependence with personality comorbidities. Addict Behav. 2014;39(11):1658–62.PubMedCrossRef Albein-Urios N, Martinez-Gonzalez JM, Lozano O, Verdejo-Garcia A. Monetary delay discounting in gambling and cocaine dependence with personality comorbidities. Addict Behav. 2014;39(11):1658–62.PubMedCrossRef
37.
go back to reference Bowden-Jones H, McPhillips M, Rogers R, Hutton S, Joyce E. Risk-taking on tests sensitive to ventromedial prefrontal cortex dysfunction predicts early relapse in alcohol dependency: a pilot study. J Neuropsychiatry Clin Neurosci. 2005;17(3):417–20.PubMedCrossRef Bowden-Jones H, McPhillips M, Rogers R, Hutton S, Joyce E. Risk-taking on tests sensitive to ventromedial prefrontal cortex dysfunction predicts early relapse in alcohol dependency: a pilot study. J Neuropsychiatry Clin Neurosci. 2005;17(3):417–20.PubMedCrossRef
38.
go back to reference Passetti F, Clark L, Mehta MA, Joyce E, King M. Neuropsychological predictors of clinical outcome in opiate addiction. Drug Alcohol Depend. 2008;94(1–3):82–91.PubMedCrossRef Passetti F, Clark L, Mehta MA, Joyce E, King M. Neuropsychological predictors of clinical outcome in opiate addiction. Drug Alcohol Depend. 2008;94(1–3):82–91.PubMedCrossRef
39.
go back to reference Verdejo-Garcia A, Betanzos-Espinosa P, Lozano OM, Vergara-Moragues E, Gonzalez-Saiz F, Fernandez-Calderon F, et al. Self-regulation and treatment retention in cocaine dependent individuals: a longitudinal study. Drug Alcohol Depend. 2012;122(1–2):142–8.PubMedCrossRef Verdejo-Garcia A, Betanzos-Espinosa P, Lozano OM, Vergara-Moragues E, Gonzalez-Saiz F, Fernandez-Calderon F, et al. Self-regulation and treatment retention in cocaine dependent individuals: a longitudinal study. Drug Alcohol Depend. 2012;122(1–2):142–8.PubMedCrossRef
40.•
go back to reference De Wilde B, Goudriaan A, Sabbe B, Hulstijn W, Dom G. Relapse in pathological gamblers: a pilot study on the predictive value of different impulsivity measures. J Behav Addict. 2013;2(1):23–30. Demonstrates that even the most common deficits in GD i.e. impulsivity (Delay Discounting Task), decision-making (IGT) and attentional bias (Stroop Colour Word Test) measured on treatment entry failed to predict abstinent from relapsed gamblers one-year later.PubMedCrossRef De Wilde B, Goudriaan A, Sabbe B, Hulstijn W, Dom G. Relapse in pathological gamblers: a pilot study on the predictive value of different impulsivity measures. J Behav Addict. 2013;2(1):23–30. Demonstrates that even the most common deficits in GD i.e. impulsivity (Delay Discounting Task), decision-making (IGT) and attentional bias (Stroop Colour Word Test) measured on treatment entry failed to predict abstinent from relapsed gamblers one-year later.PubMedCrossRef
41.
go back to reference Alvarez-Moya EM, Ochoa C, Jiménez-Murcia S, Aymamí MN, Gómez-Peña M, Fernández-Aranda F, et al. Effect of executive functioning, decision-making and self-reported impulsivity on the treatment outcome of pathologic gambling. J Psychiatry Neurosci. 2011;36(3):165–75.PubMedPubMedCentralCrossRef Alvarez-Moya EM, Ochoa C, Jiménez-Murcia S, Aymamí MN, Gómez-Peña M, Fernández-Aranda F, et al. Effect of executive functioning, decision-making and self-reported impulsivity on the treatment outcome of pathologic gambling. J Psychiatry Neurosci. 2011;36(3):165–75.PubMedPubMedCentralCrossRef
42.
go back to reference Goudriaan AE, Oosterlaan J, De Beurs E, Van Den Brink W. The role of self-reported impulsivity and reward sensitivity versus neurocognitive measures of disinhibition and decision-making in the prediction of relapse in pathological gamblers. Psychol Med. 2008;38(1):41–50.PubMedCrossRef Goudriaan AE, Oosterlaan J, De Beurs E, Van Den Brink W. The role of self-reported impulsivity and reward sensitivity versus neurocognitive measures of disinhibition and decision-making in the prediction of relapse in pathological gamblers. Psychol Med. 2008;38(1):41–50.PubMedCrossRef
43.
go back to reference Giorgetta C, Grecucci A, Rattin A, Guerreschi C, Sanfey AG, Bonini N. To play or not to play: a personal dilemma in pathological gambling. Psychiatry Res. 2014;219(3):562–9.PubMedCrossRef Giorgetta C, Grecucci A, Rattin A, Guerreschi C, Sanfey AG, Bonini N. To play or not to play: a personal dilemma in pathological gambling. Psychiatry Res. 2014;219(3):562–9.PubMedCrossRef
44.
go back to reference Verdejo-Garcia A, Lopez-Torrecillas F, Gimenez CO, Perez-Garcia M. Clinical implications and methodological challenges in the study of the neuropsychological correlates of cannabis, stimulant, and opioid abuse. Neuropsychol Rev. 2004;14(1):1–41.PubMedCrossRef Verdejo-Garcia A, Lopez-Torrecillas F, Gimenez CO, Perez-Garcia M. Clinical implications and methodological challenges in the study of the neuropsychological correlates of cannabis, stimulant, and opioid abuse. Neuropsychol Rev. 2004;14(1):1–41.PubMedCrossRef
45.
go back to reference Daw ND, Gershman SJ, Seymour B, Dayan P, Dolan RJ. Model-based influences on humans' choices and striatal prediction errors. Neuron. 2011;69(6):1204–15.PubMedPubMedCentralCrossRef Daw ND, Gershman SJ, Seymour B, Dayan P, Dolan RJ. Model-based influences on humans' choices and striatal prediction errors. Neuron. 2011;69(6):1204–15.PubMedPubMedCentralCrossRef
46.
go back to reference Oakes J, Pols R, Battersby M, Lawn S, Pulvirenti M, Smith D. A focus group study of predictors of relapse in electronic gaming machine problem gambling, part 1: factors that 'push' towards relapse. J Gambl Stud. 2012;28(3):451–64.PubMedCrossRef Oakes J, Pols R, Battersby M, Lawn S, Pulvirenti M, Smith D. A focus group study of predictors of relapse in electronic gaming machine problem gambling, part 1: factors that 'push' towards relapse. J Gambl Stud. 2012;28(3):451–64.PubMedCrossRef
47.
go back to reference Wiers CE, Stelzel C, Gladwin TE, Park SQ, Pawelczack S, Gawron CK, et al. Effects of cognitive bias modification training on neural alcohol cue reactivity in alcohol dependence. Am J Psychiatry. 2015;172(4):335–43.PubMedCrossRef Wiers CE, Stelzel C, Gladwin TE, Park SQ, Pawelczack S, Gawron CK, et al. Effects of cognitive bias modification training on neural alcohol cue reactivity in alcohol dependence. Am J Psychiatry. 2015;172(4):335–43.PubMedCrossRef
Metadata
Title
Executive Functioning in Gambling Disorder: Cognitive Profiles and Associations with Clinical Outcomes
Authors
Antonio Verdejo-Garcia
Victoria Manning
Publication date
01-09-2015
Publisher
Springer International Publishing
Published in
Current Addiction Reports / Issue 3/2015
Electronic ISSN: 2196-2952
DOI
https://doi.org/10.1007/s40429-015-0062-y

Other articles of this Issue 3/2015

Current Addiction Reports 3/2015 Go to the issue

Sex and Addiction (R Reid, Section Editor)

Debating the Conceptualization of Sex as an Addictive Disorder

Sex and Addiction (R Reid, Section Editor)

Evaluating Outcome Research for Hypersexual Behavior