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Published in: Reactions Weekly 1/2017

01-06-2017 | Case report

Metreleptin

Development of antibodies: case report

Published in: Reactions Weekly | Issue 1/2017

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Excerpt

In a case series, a 16-year-old girl was described, who developed antibodies during treatment with metreleptin. The girl, who had a history of acquired generalised lipodystrophy, started receiving treatment with SC 0.02 mg/kg metreleptin injection twice daily for one month. Later, the dose was increased to 0.04 mg/kg. Subsequently, she developed antibodies to metreleptin [duration of treatment to reaction onset and outcome not stated]. …
Literature
go back to reference Lebastchi J, et al. A report of three cases with acquired generalized lipodystrophy with distinct autoimmune conditions treated with metreleptin. Journal of Clinical Endocrinology and Metabolism 100: 3967-3970, No. 11, 2015. Available from: URL: http://doi.org/10.1210/jc.2015-2589 - USA Lebastchi J, et al. A report of three cases with acquired generalized lipodystrophy with distinct autoimmune conditions treated with metreleptin. Journal of Clinical Endocrinology and Metabolism 100: 3967-3970, No. 11, 2015. Available from: URL: http://​doi.​org/​10.​1210/​jc.​2015-2589 - USA
Metadata
Title
Metreleptin
Development of antibodies: case report
Publication date
01-06-2017
Publisher
Springer International Publishing
Published in
Reactions Weekly / Issue 1/2017
Print ISSN: 0114-9954
Electronic ISSN: 1179-2051
DOI
https://doi.org/10.1007/s40278-017-31652-5

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