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Published in: Infection 6/2013

01-12-2013 | Clinical and Epidemiological Study

Evaluation of an infectious disease consultation programme in a German tertiary care hospital

Authors: J. J. Vehreschild, G. Morgen, O. A. Cornely, P. Hartmann, S. Koch, W. Kalka-Moll, C. Wyen, M. J. G. T. Vehreschild, C. Lehmann, D. Gillor, H. Seifert, G. Kremer, G. Fätkenheuer, N. Jung

Published in: Infection | Issue 6/2013

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Abstract

Purpose

To evaluate a newly implemented infectious disease (ID) consultation service in terms of patient care, outcome and antibiotic prescription and to describe factors influencing adherence to recommendations.

Methods

Data from consultations during the first 6 months of the ID consultation program were collected and evaluated. Consultation requests, diagnostic results, treatment outcomes and antibiotic recommendations were categorised. Diagnostic and therapeutic recommendations were assessed and rated for adherence and outcome. Statistical analysis was performed to identify factors influencing adherence and treatment outcome.

Results

A total of 251 consultations were assessed. In most cases, ID specialists were asked for further advice regarding a previously initiated anti-infective treatment (N = 131, 52 %). In 54 of 195 (28 %) first consultations, the ID specialist proposed a differential diagnosis that differed from that of the working diagnoses submitted with the consultation request, and which was subsequently confirmed in 80 % of these cases. Diagnostic and therapeutic recommendations were made in 190 (76 %) and 240 (96 %) of the consultations, respectively. A change in the current treatment was recommended in 66 % of consultations; 37 % of recommendations were cost-saving and 26 % were cost-neutral. Compliance with diagnostic and therapeutic recommendations was rated as good by pre-specified criteria in 65 and 86 % of consultations, respectively. Treatment outcome was correlated with adherence to diagnostic recommendations (P = 0.012). Twenty-nine patients (16 %) died during the same hospital stay.

Conclusion

Infectious disease consultations may help to establish the correct diagnosis, resulting in the appropriate treatment being provided to a severely sick patient population. Treatment outcome was improved in cases of good diagnostic adherence to the recommendations of the ID specialist.
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Literature
4.
go back to reference Deshpande LM, Fritsche TR, Moet GJ, Biedenbach DJ, Jones RN. Antimicrobial resistance and molecular epidemiology of vancomycin-resistant enterococci from North America and Europe: a report from the SENTRY antimicrobial surveillance program. Diagn Microbiol Infect Dis. 2007;58:163–70. doi:10.1016/j.diagmicrobio.2006.12.022.PubMedCrossRef Deshpande LM, Fritsche TR, Moet GJ, Biedenbach DJ, Jones RN. Antimicrobial resistance and molecular epidemiology of vancomycin-resistant enterococci from North America and Europe: a report from the SENTRY antimicrobial surveillance program. Diagn Microbiol Infect Dis. 2007;58:163–70. doi:10.​1016/​j.​diagmicrobio.​2006.​12.​022.PubMedCrossRef
5.
go back to reference Raineri E, Pan A, Mondello P, Acquarolo A, Candiani A, Crema L. Role of the infectious diseases specialist consultant on the appropriateness of antimicrobial therapy prescription in an intensive care unit. Am J Infect Control. 2008;36:283–90. doi:10.1016/j.ajic.2007.06.009.PubMedCrossRef Raineri E, Pan A, Mondello P, Acquarolo A, Candiani A, Crema L. Role of the infectious diseases specialist consultant on the appropriateness of antimicrobial therapy prescription in an intensive care unit. Am J Infect Control. 2008;36:283–90. doi:10.​1016/​j.​ajic.​2007.​06.​009.PubMedCrossRef
6.
go back to reference Fowler VG Jr, Sanders LL, Sexton DJ, Kong L, Marr KA, Gopal AK, et al. Outcome of Staphylococcus aureus bacteremia according to compliance with recommendations of infectious diseases specialists: experience with 244 patients. Clin Infect Dis. 1998;27:478–86.PubMedCrossRef Fowler VG Jr, Sanders LL, Sexton DJ, Kong L, Marr KA, Gopal AK, et al. Outcome of Staphylococcus aureus bacteremia according to compliance with recommendations of infectious diseases specialists: experience with 244 patients. Clin Infect Dis. 1998;27:478–86.PubMedCrossRef
7.
go back to reference Jenkins TC, Price CS, Sabel AL, Mehler PS, Burman WJ. Impact of routine infectious diseases service consultation on the evaluation, management, and outcomes of Staphylococcus aureus bacteremia. Clin Infect Dis. 2008;46:1000–8. doi:10.1086/529190.PubMedCrossRef Jenkins TC, Price CS, Sabel AL, Mehler PS, Burman WJ. Impact of routine infectious diseases service consultation on the evaluation, management, and outcomes of Staphylococcus aureus bacteremia. Clin Infect Dis. 2008;46:1000–8. doi:10.​1086/​529190.PubMedCrossRef
8.
go back to reference Robinson JO, Pozzi-Langhi S, Phillips M, Pearson JC, Christiansen KJ, Coombs GW, et al. Formal infectious diseases consultation is associated with decreased mortality in Staphylococcus aureus bacteraemia. Eur J Clin Microbiol Infect Dis. 2012;31:2421–8. doi:10.1007/s10096-012-1585-y.PubMedCrossRef Robinson JO, Pozzi-Langhi S, Phillips M, Pearson JC, Christiansen KJ, Coombs GW, et al. Formal infectious diseases consultation is associated with decreased mortality in Staphylococcus aureus bacteraemia. Eur J Clin Microbiol Infect Dis. 2012;31:2421–8. doi:10.​1007/​s10096-012-1585-y.PubMedCrossRef
9.
10.
11.
go back to reference Forsblom E, Ruotsalainen E, Ollgren J, Jarvinen A. Telephone consultation cannot replace bedside infectious disease consultation in the management of Staphylococcus aureus Bacteremia. Clin Infect Dis. 2013;56:527–35. doi:10.1093/cid/cis889.PubMedCrossRef Forsblom E, Ruotsalainen E, Ollgren J, Jarvinen A. Telephone consultation cannot replace bedside infectious disease consultation in the management of Staphylococcus aureus Bacteremia. Clin Infect Dis. 2013;56:527–35. doi:10.​1093/​cid/​cis889.PubMedCrossRef
12.
go back to reference Gomez J, Conde Cavero SJ, Hernandez Cardona JL, Nunez ML, Ruiz Gomez J, Canteras M, et al. The influence of the opinion of an infectious disease consultant on the appropriateness of antibiotic treatment in a general hospital. J Antimicrob Chemother. 1996;38:309–14.PubMedCrossRef Gomez J, Conde Cavero SJ, Hernandez Cardona JL, Nunez ML, Ruiz Gomez J, Canteras M, et al. The influence of the opinion of an infectious disease consultant on the appropriateness of antibiotic treatment in a general hospital. J Antimicrob Chemother. 1996;38:309–14.PubMedCrossRef
13.
14.
go back to reference Sellier E, Pavese P, Gennai S, Stahl JP, Labarere J, Francois P. Factors and outcomes associated with physicians’ adherence to recommendations of infectious disease consultations for inpatients. J Antimicrob Chemother. 2010;65:156–62. doi:10.1093/jac/dkp406.PubMedCrossRef Sellier E, Pavese P, Gennai S, Stahl JP, Labarere J, Francois P. Factors and outcomes associated with physicians’ adherence to recommendations of infectious disease consultations for inpatients. J Antimicrob Chemother. 2010;65:156–62. doi:10.​1093/​jac/​dkp406.PubMedCrossRef
15.
go back to reference John JF Jr, Fishman NO. Programmatic role of the infectious diseases physician in controlling antimicrobial costs in the hospital. Clin Infect Dis. 1997;24:471–85.PubMedCrossRef John JF Jr, Fishman NO. Programmatic role of the infectious diseases physician in controlling antimicrobial costs in the hospital. Clin Infect Dis. 1997;24:471–85.PubMedCrossRef
17.
19.
go back to reference Lo E, Rezai K, Evans AT, Madariaga MG, Phillips M, Brobbey W, et al. Why don’t they listen? Adherence to recommendations of infectious disease consultations. Clin Infect Dis. 2004;38:1212–8. doi:10.1086/383315.PubMedCrossRef Lo E, Rezai K, Evans AT, Madariaga MG, Phillips M, Brobbey W, et al. Why don’t they listen? Adherence to recommendations of infectious disease consultations. Clin Infect Dis. 2004;38:1212–8. doi:10.​1086/​383315.PubMedCrossRef
20.
21.
go back to reference Sellier E, Labarere J, Gennai S, Bal G, Francois P, Pavese P. Compliance with recommendations and clinical outcomes for formal and informal infectious disease specialist consultations. Eur J Clin Microbiol Infect Dis. 2011;30:887–94. doi:10.1007/s10096-011-1172-7.PubMedCrossRef Sellier E, Labarere J, Gennai S, Bal G, Francois P, Pavese P. Compliance with recommendations and clinical outcomes for formal and informal infectious disease specialist consultations. Eur J Clin Microbiol Infect Dis. 2011;30:887–94. doi:10.​1007/​s10096-011-1172-7.PubMedCrossRef
23.
go back to reference Pulcini C, Pradier C, Samat-Long C, Hyvernat H, Bernardin G, Ichai C, et al. Factors associated with adherence to infectious diseases advice in two intensive care units. J Antimicrob Chemother. 2006;57:546–50. doi:10.1093/jac/dki483.PubMedCrossRef Pulcini C, Pradier C, Samat-Long C, Hyvernat H, Bernardin G, Ichai C, et al. Factors associated with adherence to infectious diseases advice in two intensive care units. J Antimicrob Chemother. 2006;57:546–50. doi:10.​1093/​jac/​dki483.PubMedCrossRef
27.
28.
go back to reference Paul M, Shani V, Muchtar E, Kariv G, Robenshtok E, Leibovici L. Systematic review and meta-analysis of the efficacy of appropriate empiric antibiotic therapy for sepsis. Antimicrob Agents Chemother. 2010;54:4851–63. doi:10.1128/AAC.00627-10.PubMedCrossRef Paul M, Shani V, Muchtar E, Kariv G, Robenshtok E, Leibovici L. Systematic review and meta-analysis of the efficacy of appropriate empiric antibiotic therapy for sepsis. Antimicrob Agents Chemother. 2010;54:4851–63. doi:10.​1128/​AAC.​00627-10.PubMedCrossRef
30.
go back to reference Thu TA, Rahman M, Coffin S, Harun-Or-Rashid M, Sakamoto J, Hung NV. Antibiotic use in Vietnamese hospitals: a multicenter point-prevalence study. Am J Infect Control. 2012;40:840–4. doi:10.1016/j.ajic.2011.10.020. Thu TA, Rahman M, Coffin S, Harun-Or-Rashid M, Sakamoto J, Hung NV. Antibiotic use in Vietnamese hospitals: a multicenter point-prevalence study. Am J Infect Control. 2012;40:840–4. doi:10.​1016/​j.​ajic.​2011.​10.​020.
Metadata
Title
Evaluation of an infectious disease consultation programme in a German tertiary care hospital
Authors
J. J. Vehreschild
G. Morgen
O. A. Cornely
P. Hartmann
S. Koch
W. Kalka-Moll
C. Wyen
M. J. G. T. Vehreschild
C. Lehmann
D. Gillor
H. Seifert
G. Kremer
G. Fätkenheuer
N. Jung
Publication date
01-12-2013
Publisher
Springer Berlin Heidelberg
Published in
Infection / Issue 6/2013
Print ISSN: 0300-8126
Electronic ISSN: 1439-0973
DOI
https://doi.org/10.1007/s15010-013-0512-1

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