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Infection
Published in: Infection 2/2011

01-04-2011 | Clinical and Epidemiological Study

G2 as an emerging rotavirus strain in pediatric gastroenteritis in southern Italy

Authors: E. Finamore, M. Vitiello, A. Kampanaraki, M. Rao, Massimiliano Galdiero, E. Galdiero, P. Bevilacqua, M. A. Gallo, Marilena Galdiero

Published in: Infection | Issue 2/2011

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Abstract

Background

Human rotaviruses (HRVs) represent a major cause of acute gastroenteritis in children worldwide. It is estimated that they are responsible for a large number of diarrhea-associated hospitalizations in childhood each year. In Italy, limited data are available on the patterns of distribution of HRV G and P types. We report here the results of 2 years of rotavirus strain surveillance among children with severe gastroenteritis diagnosed in the town of Portici, Campania, southern Italy.

Methods

A total of 421 stool specimens from children between 6 months and 5 years of age and presenting acute diarrhea were collected and tested by routine diagnostic tests for HRV, adenovirus, astrovirus, norovirus, and common bacterial pathogens.

Results

The laboratory results showed that 110 of the 225 (26.1%) virus-positive samples contained HRVs. The different G and P rotavirus genotypes were analyzed by polymerase chain reaction (PCR). Among the VP7 genotypes identified, G1 and G2 were predominant, with percentages of 48.2 and 30.9%, respectively. G4, G9, and G10 were detected in a minority of cases. Among the VP4 genotypes, P[8] occurred the most frequently (56.4%), followed by P[4] (31.8%), and only a few P[10] and P[11] at percentages of 1.8 and 0.9%, respectively.

Conclusion

Our epidemiological data of HRV strains will contribute to assessing the magnitude of the problem of HRV in the south of Italy.
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Metadata
Title
G2 as an emerging rotavirus strain in pediatric gastroenteritis in southern Italy
Authors
E. Finamore
M. Vitiello
A. Kampanaraki
M. Rao
Massimiliano Galdiero
E. Galdiero
P. Bevilacqua
M. A. Gallo
Marilena Galdiero
Publication date
01-04-2011
Publisher
Springer-Verlag
Published in
Infection / Issue 2/2011
Print ISSN: 0300-8126
Electronic ISSN: 1439-0973
DOI
https://doi.org/10.1007/s15010-011-0102-z

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