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Published in: Infection 5/2010

01-10-2010 | Correspondence

Lemierre syndrome caused by co-infection by Arcanobacterium haemolyticum and Fusobacterium necrophorum

Authors: K. Lundblom, K. Jung, M. Kalin

Published in: Infection | Issue 5/2010

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Excerpt

In 1936, Lemierre described a series of cases with anaerobic sepsis following primary oropharyngeal infection. These ‘postanginal septicemias’, subsequently denoted ‘Lemierre syndrome’ or ‘Lemierre’s disease’, were characterized by septic thrombophlebitis of the jugular venous system and multiple metastatic abscesses which were most commonly found in the lungs. The syndrome had a high case-fatality rate and affected mainly young adults [1]. Although polymicrobial infections have been reported, the main pathogen in Lemierre syndrome is Fusobacterium necrophorum, an obligate anaerobic, Gram-negative rod [2]. Disseminated infections are rare. The highest incidence occurs in the age group 15–24 years [3]. …
Literature
1.
go back to reference Lemierre A. On certain septicemias due to anaerobic organisms. Lancet. 1936;1:701–3.CrossRef Lemierre A. On certain septicemias due to anaerobic organisms. Lancet. 1936;1:701–3.CrossRef
2.
go back to reference Sinave CP, Hardy GJ, Fardy PW. The Lemierre syndrome: suppurative thrombophlebitis of the internal jugular vein secondary to oropharyngeal infection. Medicine (Baltimore). 1989;68:85–94. Sinave CP, Hardy GJ, Fardy PW. The Lemierre syndrome: suppurative thrombophlebitis of the internal jugular vein secondary to oropharyngeal infection. Medicine (Baltimore). 1989;68:85–94.
3.
go back to reference Hagelskjaer Kristensen L, Prag J. Lemierre’s syndrome and other disseminated Fusobacterium necrophorum infections in Denmark: a prospective epidemiological and clinical survey. Eur J Clin Microbiol Infect Dis. 2008;27:779–89.CrossRefPubMed Hagelskjaer Kristensen L, Prag J. Lemierre’s syndrome and other disseminated Fusobacterium necrophorum infections in Denmark: a prospective epidemiological and clinical survey. Eur J Clin Microbiol Infect Dis. 2008;27:779–89.CrossRefPubMed
4.
go back to reference Linder R. Rhodococcus equi and Arcanobacterium haemolyticum: two “coryneform” bacteria increasingly recognized as agents of human infection. Emerg Infect Dis. 1997;3:145–53.CrossRefPubMed Linder R. Rhodococcus equi and Arcanobacterium haemolyticum: two “coryneform” bacteria increasingly recognized as agents of human infection. Emerg Infect Dis. 1997;3:145–53.CrossRefPubMed
5.
go back to reference Mackenzie A, Fuite LA, Chan FT, et al. Incidence and pathogenicity of Arcanobacterium haemolyticum during a 2-year study in Ottawa. Clin Infect Dis. 1995;21:177–81.PubMed Mackenzie A, Fuite LA, Chan FT, et al. Incidence and pathogenicity of Arcanobacterium haemolyticum during a 2-year study in Ottawa. Clin Infect Dis. 1995;21:177–81.PubMed
6.
go back to reference Younus F, Chua A, Tortora G, Jimenez VE. Lemierre’s disease caused by co-infection of Arcanobacterium haemolyticum and Fusobacterium necrophorum: a case report. J Infect. 2002;45:114–7.CrossRefPubMed Younus F, Chua A, Tortora G, Jimenez VE. Lemierre’s disease caused by co-infection of Arcanobacterium haemolyticum and Fusobacterium necrophorum: a case report. J Infect. 2002;45:114–7.CrossRefPubMed
7.
go back to reference Ludlam H, Howard J, Kingston B, et al. Epidemiology of pharyngeal carriage of Fusobacterium necrophorum. J Med Microbiol. 2009;58:1264–5.CrossRefPubMed Ludlam H, Howard J, Kingston B, et al. Epidemiology of pharyngeal carriage of Fusobacterium necrophorum. J Med Microbiol. 2009;58:1264–5.CrossRefPubMed
8.
go back to reference Hagelskjær L, Kristensen JP. Localised Fusobacterium necrophorum infections: a prospective laboratory-based Danish study. Eur J Clin Microbiol Infect Dis. 2008;27:733–9.CrossRef Hagelskjær L, Kristensen JP. Localised Fusobacterium necrophorum infections: a prospective laboratory-based Danish study. Eur J Clin Microbiol Infect Dis. 2008;27:733–9.CrossRef
9.
go back to reference Therriault BL, Daniels LM, Carter YL, Raasch RH. Severe sepsis caused by Arcanobacterium haemolyticum: a case report and review of the literature. Ann Pharmacother. 2008;42:1697–702.CrossRefPubMed Therriault BL, Daniels LM, Carter YL, Raasch RH. Severe sepsis caused by Arcanobacterium haemolyticum: a case report and review of the literature. Ann Pharmacother. 2008;42:1697–702.CrossRefPubMed
Metadata
Title
Lemierre syndrome caused by co-infection by Arcanobacterium haemolyticum and Fusobacterium necrophorum
Authors
K. Lundblom
K. Jung
M. Kalin
Publication date
01-10-2010
Publisher
Urban and Vogel
Published in
Infection / Issue 5/2010
Print ISSN: 0300-8126
Electronic ISSN: 1439-0973
DOI
https://doi.org/10.1007/s15010-010-0046-8

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