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Acta Neurologica Belgica
Published in: Acta Neurologica Belgica 5/2021

01-10-2021 | Visceral Ischemia | Letter to the Editor

Late-onset of primary antiphospholipid syndrome: a case report

Authors: Adam Benkirane, Bérangère Devalet, Pauline Montigny, Frédéric London

Published in: Acta Neurologica Belgica | Issue 5/2021

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Excerpt

Antiphospholipid syndrome (APS) is a rare autoantibody-mediated acquired disorder characterized by thrombotic events and/or obstetrical morbidities, with persistent antiphospholipid (aPL) antibodies (Abs) [1]. Its diagnosis requires persistent positivity in at least one of three aPL tests conducted on two or more occasions at least 12 weeks apart [1]. APS is likely to be diagnosed in early adulthood and is far more common in women [2, 3]. Onset of APS over the age of 50 is however rare [4]. Here, we describe a case of late-onset of triple-positive primary APS. …
Literature
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Miyakis S, Lockshin MD, Atsumi T et al (2006) International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS). J Thromb Haemost 4(2):295–306CrossRef
2.
Gómez-Puerta J, Cervera R (2014) Diagnosis and classification of the antiphospholipid syndrome. J Autoimmun 48–49:20–25CrossRef
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George MG (2020) Risk factors for ischemic stroke in younger adults—a focused update. Stroke 51(3):729–735CrossRef
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Cervera R, Piette JC, Font J et al (2002) Antiphospholipid syndrome: clinical and immunologic manifestations and patterns of disease expression in a cohort of 1,000 patients. Arthritis Rheum 46:1019–1027CrossRef
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Pengo V, Ruffatti A, Legnani C, Gresele P, Barcellona D, Erba N et al (2010) Clinical course of high-risk patients diagnosed with antiphospholipid syndrome. J Thromb Haemost 8:237–242CrossRef
Metadata
Title
Late-onset of primary antiphospholipid syndrome: a case report
Authors
Adam Benkirane
Bérangère Devalet
Pauline Montigny
Frédéric London
Publication date
01-10-2021
Publisher
Springer International Publishing
Published in
Acta Neurologica Belgica / Issue 5/2021
Print ISSN: 0300-9009
Electronic ISSN: 2240-2993
DOI
https://doi.org/10.1007/s13760-020-01555-4

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