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Acta Neurologica Belgica
Published in: Acta Neurologica Belgica 3/2013

01-09-2013 | Letter to the Editor

Treatment of NMO relapse in the elderly: rituximab when plasma exchange fails?

Authors: B. Bourre, R. Lefaucheur, C. Girault

Published in: Acta Neurologica Belgica | Issue 3/2013

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Excerpt

Neuromyelitis optica (NMO) is a rare demyelinating central nervous system disease that causes longitudinal extensive transverse myelitis (LETM) and optic neuritis (ON). There are no clear guidelines for the management of relapses. We report plasma exchange (PE) failure in two elderly NMO patients and the success of rituximab therapy. …
Literature
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Lefaucheur R, Bourre B, Ahtoy P, Ozkul O, Tollard E, Hannequin D et al (2011) Neuromyelitis optica with very late onset. J Am Geriatr Soc 59(6):1138–1140PubMedCrossRef
2.
Kim SH, Kim W, Li XF, Jung IJ, Kim HJ (2011) Repeated treatment with rituximab based on the assessment of peripheral circulating memory B cells in patients with relapsing neuromyelitis optica over 2 years. Arch Neurol 68(11):1412–1420PubMedCrossRef
3.
Sellner J, Boggild M, Clanet M, Hintzen RQ, Illes Z, Montalban X et al (2010) EFNS guidelines on diagnosis and management of neuromyelitis optica. Eur J Neurol 17(8):1019–1032PubMedCrossRef
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Basic-Jukic N, Brunetta B, Kes P (2010) Plasma exchange in elderly patients. Ther Apher Dial. 14(2):161–165PubMedCrossRef
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Abdel-Rahman EM, Hayes J, Balogun RA (2012) Therapeutic plasma exchange in the elderly: experience at a tertiary center. J Clin Apher. 27(3):108–111PubMedCrossRef
Metadata
Title
Treatment of NMO relapse in the elderly: rituximab when plasma exchange fails?
Authors
B. Bourre
R. Lefaucheur
C. Girault
Publication date
01-09-2013
Publisher
Springer Milan
Published in
Acta Neurologica Belgica / Issue 3/2013
Print ISSN: 0300-9009
Electronic ISSN: 2240-2993
DOI
https://doi.org/10.1007/s13760-013-0178-6

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