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Published in: International Cancer Conference Journal 2/2015

01-04-2015 | Case report

Application of cervical epidural anesthesia in patients with head and neck carcinoma

Authors: Hiroki Sato, Kiyoaki Tsukahara, Ray Motohashi, Minoru Endo, Kazuhiro Nakamura

Published in: International Cancer Conference Journal | Issue 2/2015

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Abstract

In head and neck carcinoma surgery, we often encounter patients for whom there is high risk in operations under general anesthesia (GA) with artificial ventilation management, such as elderly patients or those with comorbidities or impaired organ function. Three patients with head and neck carcinoma for whom risks were high under general anesthesia underwent surgery under cervical epidural anesthesia (CEA). The first case is 67-year-old male with cT2N3M0 laryngeal carcinoma. The patient had several medical history such as angina pectoris, renal impairment developed following cisplatin administration and combined ventilator impairment. Right neck dissection was performed (Level I–IV) under CEA. A decrease in blood pressure was observed during surgery, but was controlled with a small dose of vasopressor and fluid replenishment. The second case is 83-year-old female with cT4aN0M0 submandibular gland carcinoma. She had a history of chronic thoracic empyema and severe respiratory dysfunction was observed. Right submandibular gland carcinoma resection and neck dissection (Level I) were performed under CEA. As respiratory depression occurred following anesthesia induction, tracheotomy was performed and artificial ventilation management was still required after surgery had been completed. The third case is 87-year-old male with rT2N0M0 laryngeal carcinoma. Total laryngectomy was performed under CEA. In Case 2, other than the respiratory problems, no other complications were observed during or after surgery. Operation time and amount of hemorrhage were again comparable to those for surgery under GA. For patients at high risk under GA or with systemic diseases or impaired organ function, CEA represents a therapeutic option.
Literature
1.
go back to reference Bonica JJ (1953) Technic of nerve blocking. In: The autonomic nervous system. Lea & Febiger, Philadelphia p 373 Bonica JJ (1953) Technic of nerve blocking. In: The autonomic nervous system. Lea & Febiger, Philadelphia p 373
2.
3.
go back to reference Catchlove RFH, Braha R (1984) The use of cervical epidural nerve blocks in the management of chronic head and neck pain. Can Anaesth Soc J 31:188–191CrossRefPubMed Catchlove RFH, Braha R (1984) The use of cervical epidural nerve blocks in the management of chronic head and neck pain. Can Anaesth Soc J 31:188–191CrossRefPubMed
4.
go back to reference Green CD (1963) Cervical epidural anesthesia for carotid endarterectiomy. Surg Gynecol Obstet 117:366–367PubMed Green CD (1963) Cervical epidural anesthesia for carotid endarterectiomy. Surg Gynecol Obstet 117:366–367PubMed
5.
go back to reference Prades JM, Navez ML, Martin C (1987) Locoregional anesthesia by peri-dural route in neck surgery. Ann Otolaryngol Chir Cervicofac 104(8):587–591 (in French)PubMed Prades JM, Navez ML, Martin C (1987) Locoregional anesthesia by peri-dural route in neck surgery. Ann Otolaryngol Chir Cervicofac 104(8):587–591 (in French)PubMed
6.
go back to reference Bromage PR (1967) Physiology and pharmacology of epidural analgesia: a review. Anesthesiology 28:592–622CrossRefPubMed Bromage PR (1967) Physiology and pharmacology of epidural analgesia: a review. Anesthesiology 28:592–622CrossRefPubMed
7.
go back to reference Dohi S, Takeshima R, Naito H (1986) Ventilatory and circulatory responses to carbon dioxide and high level sympathectomy induced by epidural blockade in awake humans. Anesth Analg 65:9–14CrossRefPubMed Dohi S, Takeshima R, Naito H (1986) Ventilatory and circulatory responses to carbon dioxide and high level sympathectomy induced by epidural blockade in awake humans. Anesth Analg 65:9–14CrossRefPubMed
8.
go back to reference Takasaki M, Takahashi T (1980) Respiratory function during cervical and thoracic extradural analgesia in patients with normal lungs. Br J Anesth 52:1271–1275CrossRef Takasaki M, Takahashi T (1980) Respiratory function during cervical and thoracic extradural analgesia in patients with normal lungs. Br J Anesth 52:1271–1275CrossRef
9.
go back to reference Negre I, Gueneron JP, Ecoffey C et al (1987) Ventilatory response to carbon dioxide after intramuscular and epidural fentanyl. Anesth Analg 66:707–710CrossRefPubMed Negre I, Gueneron JP, Ecoffey C et al (1987) Ventilatory response to carbon dioxide after intramuscular and epidural fentanyl. Anesth Analg 66:707–710CrossRefPubMed
Metadata
Title
Application of cervical epidural anesthesia in patients with head and neck carcinoma
Authors
Hiroki Sato
Kiyoaki Tsukahara
Ray Motohashi
Minoru Endo
Kazuhiro Nakamura
Publication date
01-04-2015
Publisher
Springer Japan
Published in
International Cancer Conference Journal / Issue 2/2015
Electronic ISSN: 2192-3183
DOI
https://doi.org/10.1007/s13691-014-0183-5

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