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Neurotherapeutics
Published in: Neurotherapeutics 2/2016

01-04-2016 | Current Perspectives

Sleep, Sleep Disorders, and Mild Traumatic Brain Injury. What We Know and What We Need to Know: Findings from a National Working Group

Authors: Emerson M. Wickwire, Scott G. Williams, Thomas Roth, Vincent F. Capaldi, Michael Jaffe, Margaret Moline, Gholam K. Motamedi, Gregory W. Morgan, Vincent Mysliwiec, Anne Germain, Renee M. Pazdan, Reuven Ferziger, Thomas J. Balkin, Margaret E. MacDonald, Thomas A. Macek, Michael R. Yochelson, Steven M. Scharf, Christopher J. Lettieri

Published in: Neurotherapeutics | Issue 2/2016

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Abstract

Disturbed sleep is one of the most common complaints following traumatic brain injury (TBI) and worsens morbidity and long-term sequelae. Further, sleep and TBI share neurophysiologic underpinnings with direct relevance to recovery from TBI. As such, disturbed sleep and clinical sleep disorders represent modifiable treatment targets to improve outcomes in TBI. This paper presents key findings from a national working group on sleep and TBI, with a specific focus on the testing and development of sleep-related therapeutic interventions for mild TBI (mTBI). First, mTBI and sleep physiology are briefly reviewed. Next, essential empirical and clinical questions and knowledge gaps are addressed. Finally, actionable recommendations are offered to guide active and efficient collaboration between academic, industry, and governmental stakeholders.
Appendix
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Metadata
Title
Sleep, Sleep Disorders, and Mild Traumatic Brain Injury. What We Know and What We Need to Know: Findings from a National Working Group
Authors
Emerson M. Wickwire
Scott G. Williams
Thomas Roth
Vincent F. Capaldi
Michael Jaffe
Margaret Moline
Gholam K. Motamedi
Gregory W. Morgan
Vincent Mysliwiec
Anne Germain
Renee M. Pazdan
Reuven Ferziger
Thomas J. Balkin
Margaret E. MacDonald
Thomas A. Macek
Michael R. Yochelson
Steven M. Scharf
Christopher J. Lettieri
Publication date
01-04-2016
Publisher
Springer US
Published in
Neurotherapeutics / Issue 2/2016
Print ISSN: 1933-7213
Electronic ISSN: 1878-7479
DOI
https://doi.org/10.1007/s13311-016-0429-3

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