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Published in: Insights into Imaging 4/2012

Open Access 01-08-2012 | Guideline

MRI of the lung (2/3). Why … when … how?

Authors: J. Biederer, M. Beer, W. Hirsch, J. Wild, M. Fabel, M. Puderbach, E. J. R. Van Beek

Published in: Insights into Imaging | Issue 4/2012

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Abstract

Background

Among the modalities for lung imaging, proton magnetic resonance imaging (MRI) has been the latest to be introduced into clinical practice. Its value to replace X-ray and computed tomography (CT) when radiation exposure or iodinated contrast material is contra-indicated is well acknowledged: i.e. for paediatric patients and pregnant women or for scientific use. One of the reasons why MRI of the lung is still rarely used, except in a few centres, is the lack of consistent protocols customised to clinical needs.

Methods

This article makes non-vendor-specific protocol suggestions for general use with state-of-the-art MRI scanners, based on the available literature and a consensus discussion within a panel of experts experienced in lung MRI.

Results

Various sequences have been successfully tested within scientific or clinical environments. MRI of the lung with appropriate combinations of these sequences comprises morphological and functional imaging aspects in a single examination. It serves in difficult clinical problems encountered in daily routine, such as assessment of the mediastinum and chest wall, and even might challenge molecular imaging techniques in the near future.

Conclusion

This article helps new users to implement appropriate protocols on their own MRI platforms.
Main Messages
MRI of the lung can be readily performed on state-of-the-art 1.5-T MRI scanners.
Protocol suggestions based on the available literature facilitate its use for routine
MRI offers solutions for complicated thoracic masses with atelectasis and chest wall invasion.
MRI is an option for paediatrics and science when CT is contra-indicated
Literature
1.
go back to reference Puderbach M, Hintze C, Ley S, Eichinger M, Kauczor H-U, Biederer J (2007) MR imaging of the chest: a practical approach at 1.5 T. Eur J Radiol 64:345–55PubMedCrossRef Puderbach M, Hintze C, Ley S, Eichinger M, Kauczor H-U, Biederer J (2007) MR imaging of the chest: a practical approach at 1.5 T. Eur J Radiol 64:345–55PubMedCrossRef
2.
go back to reference Eibel R, Herzog P, Dietrich O, Rieger CT, Ostermann H, Reiser MF, Schoenberg SO (2006) Pulmonary abnormalities in immunocompromised patients: comparative detection with parallel acquisition MR imaging and thin-section helical CT. Radiology 241:880–891PubMedCrossRef Eibel R, Herzog P, Dietrich O, Rieger CT, Ostermann H, Reiser MF, Schoenberg SO (2006) Pulmonary abnormalities in immunocompromised patients: comparative detection with parallel acquisition MR imaging and thin-section helical CT. Radiology 241:880–891PubMedCrossRef
3.
go back to reference Biederer J (2005) Magnetic resonance imaging: technical aspects and recent developments. Med Klin (Munich) 100:62–72PubMedCrossRef Biederer J (2005) Magnetic resonance imaging: technical aspects and recent developments. Med Klin (Munich) 100:62–72PubMedCrossRef
4.
go back to reference Lotz J, Kivelitz D, Fischbach R, Beer M, Miller S (2009) Recommendations for utilizing computerized tomography and magnetic resonance tomography in heart diagnosis. 2–Magnetic resonance tomography. Rofo 181:800–814PubMedCrossRef Lotz J, Kivelitz D, Fischbach R, Beer M, Miller S (2009) Recommendations for utilizing computerized tomography and magnetic resonance tomography in heart diagnosis. 2–Magnetic resonance tomography. Rofo 181:800–814PubMedCrossRef
5.
go back to reference Biederer J, Bauman G, Hintze C, Fabel M, Both M (2011) Magnetresonanztomographie. Der Pneumologe 8:234–242CrossRef Biederer J, Bauman G, Hintze C, Fabel M, Both M (2011) Magnetresonanztomographie. Der Pneumologe 8:234–242CrossRef
6.
go back to reference Bankier AA, O’Donnell CR, Mai VM, Storey P, De Maertelaer V, Edelman RR, Chen Q (2004) Impact of lung volume on MR signal intensity changes of the lung parenchyma. J Magn Reson Imaging 20:961–966PubMedCrossRef Bankier AA, O’Donnell CR, Mai VM, Storey P, De Maertelaer V, Edelman RR, Chen Q (2004) Impact of lung volume on MR signal intensity changes of the lung parenchyma. J Magn Reson Imaging 20:961–966PubMedCrossRef
7.
go back to reference Bauman G, Puderbach M, Deimling M, Jellus V, Chefd’hotel C, Dinkel J, Hintze C, Kauczor H-U, Schad LR (2009) Non-contrast-enhanced perfusion and ventilation assessment of the human lung by means of fourier decomposition in proton MRI. Magn Reson Med 62:656–664PubMedCrossRef Bauman G, Puderbach M, Deimling M, Jellus V, Chefd’hotel C, Dinkel J, Hintze C, Kauczor H-U, Schad LR (2009) Non-contrast-enhanced perfusion and ventilation assessment of the human lung by means of fourier decomposition in proton MRI. Magn Reson Med 62:656–664PubMedCrossRef
9.
go back to reference Iwasawa T, Takahashi H, Ogura T, Asakura A, Gotoh T, Kagei S, J-ichi N, Obara M, Inoue T (2007) Correlation of lung parenchymal MR signal intensity with pulmonary function tests and quantitative computed tomography (CT) evaluation: a pilot study. J Magn Reson Imaging 26:1530–1536PubMedCrossRef Iwasawa T, Takahashi H, Ogura T, Asakura A, Gotoh T, Kagei S, J-ichi N, Obara M, Inoue T (2007) Correlation of lung parenchymal MR signal intensity with pulmonary function tests and quantitative computed tomography (CT) evaluation: a pilot study. J Magn Reson Imaging 26:1530–1536PubMedCrossRef
10.
go back to reference Bauman G, Lützen U, Ullrich M, Gaass T, Dinkel J, Elke G, Meybohm P, Frerichs I, Hoffmann B et al (2011) Pulmonary functional imaging: qualitative comparison of Fourier decomposition MR imaging with SPECT/CT in porcine lung. Radiology 260:551–559PubMedCrossRef Bauman G, Lützen U, Ullrich M, Gaass T, Dinkel J, Elke G, Meybohm P, Frerichs I, Hoffmann B et al (2011) Pulmonary functional imaging: qualitative comparison of Fourier decomposition MR imaging with SPECT/CT in porcine lung. Radiology 260:551–559PubMedCrossRef
11.
go back to reference Ley-Zaporozhan J, Ley S, Eberhardt R, Kauczor H-U, Heussel CP (2010) Visualization of morphological parenchymal changes in emphysema: comparison of different MRI sequences to 3D-HRCT. Eur J Radiol 73:43–49PubMedCrossRef Ley-Zaporozhan J, Ley S, Eberhardt R, Kauczor H-U, Heussel CP (2010) Visualization of morphological parenchymal changes in emphysema: comparison of different MRI sequences to 3D-HRCT. Eur J Radiol 73:43–49PubMedCrossRef
12.
go back to reference Biederer J, Busse I, Grimm J, Reuter M, Muhle C, Freitag S, Heller M (2002) Sensitivity of MRI in detecting alveolar Infiltrates: Experimental studies. Rofo 174:1033–9PubMedCrossRef Biederer J, Busse I, Grimm J, Reuter M, Muhle C, Freitag S, Heller M (2002) Sensitivity of MRI in detecting alveolar Infiltrates: Experimental studies. Rofo 174:1033–9PubMedCrossRef
13.
go back to reference Kersjes W, Hildebrandt G, Cagil H, Schunk K, von Zitzewitz H, Schild H (1999) Differentiation of alveolitis and pulmonary fibrosis in rabbits with magnetic resonance imaging after intrabronchial administration of bleomycin. Invest Radiol 34:13–21PubMedCrossRef Kersjes W, Hildebrandt G, Cagil H, Schunk K, von Zitzewitz H, Schild H (1999) Differentiation of alveolitis and pulmonary fibrosis in rabbits with magnetic resonance imaging after intrabronchial administration of bleomycin. Invest Radiol 34:13–21PubMedCrossRef
14.
go back to reference Fink C, Puderbach M, Biederer J, Fabel M, Dietrich O, Kauczor H-U, Reiser MF, Schönberg SO (2007) Lung MRI at 1.5 and 3 Tesla: observer preference study and lesion contrast using five different pulse sequences. Invest Radiol 42:377–83PubMedCrossRef Fink C, Puderbach M, Biederer J, Fabel M, Dietrich O, Kauczor H-U, Reiser MF, Schönberg SO (2007) Lung MRI at 1.5 and 3 Tesla: observer preference study and lesion contrast using five different pulse sequences. Invest Radiol 42:377–83PubMedCrossRef
15.
go back to reference Jacob RE, Amidan BG, Soelberg J, Minard KR (2010) In vivo MRI of altered proton signal intensity and T2 relaxation in a bleomycin model of pulmonary inflammation and fibrosis. J Magn Reson Imaging 31:1091–1099PubMedCrossRef Jacob RE, Amidan BG, Soelberg J, Minard KR (2010) In vivo MRI of altered proton signal intensity and T2 relaxation in a bleomycin model of pulmonary inflammation and fibrosis. J Magn Reson Imaging 31:1091–1099PubMedCrossRef
16.
go back to reference Rieger C, Herzog P, Eibel R, Fiegl M, Ostermann H (2008) Pulmonary MRI–a new approach for the evaluation of febrile neutropenic patients with malignancies. Support Care Cancer 16:599–606PubMedCrossRef Rieger C, Herzog P, Eibel R, Fiegl M, Ostermann H (2008) Pulmonary MRI–a new approach for the evaluation of febrile neutropenic patients with malignancies. Support Care Cancer 16:599–606PubMedCrossRef
17.
go back to reference Fink C, Puderbach M, Biederer J, Fabel M, Dietrich O, Kauczor H-U, Reiser MF, Schönberg SO (2007) Lung MRI at 1.5 and 3 Tesla: observer preference study and lesion contrast using five different pulse sequences. Invest Radiol 42:377–83PubMedCrossRef Fink C, Puderbach M, Biederer J, Fabel M, Dietrich O, Kauczor H-U, Reiser MF, Schönberg SO (2007) Lung MRI at 1.5 and 3 Tesla: observer preference study and lesion contrast using five different pulse sequences. Invest Radiol 42:377–83PubMedCrossRef
18.
go back to reference Biederer J, Schoene A, Freitag S, Reuter M, Heller M (2003) Simulated pulmonary nodules implanted in a dedicated porcine chest phantom: sensitivity of MR imaging for detection. Radiology 227:475–83PubMedCrossRef Biederer J, Schoene A, Freitag S, Reuter M, Heller M (2003) Simulated pulmonary nodules implanted in a dedicated porcine chest phantom: sensitivity of MR imaging for detection. Radiology 227:475–83PubMedCrossRef
19.
go back to reference Both M, Schultze J, Reuter M, Bewig B, Hubner R, Bobis I, Noth R, Heller M, Biederer J (2005) Fast T1- and T2-weighted pulmonary MR-imaging in patients with bronchial carcinoma. Eur J Radiol 53:478–88PubMedCrossRef Both M, Schultze J, Reuter M, Bewig B, Hubner R, Bobis I, Noth R, Heller M, Biederer J (2005) Fast T1- and T2-weighted pulmonary MR-imaging in patients with bronchial carcinoma. Eur J Radiol 53:478–88PubMedCrossRef
20.
go back to reference Bruegel M, Gaa J, Woertler K, Ganter C, Waldt S, Hillerer C, Rummeny EJ (2007) MRI of the lung: value of different turbo spin-echo, single-shot turbo spin-echo, and 3D gradient-echo pulse sequences for the detection of pulmonary metastases. J Magn Reson Imaging 25:73–81PubMedCrossRef Bruegel M, Gaa J, Woertler K, Ganter C, Waldt S, Hillerer C, Rummeny EJ (2007) MRI of the lung: value of different turbo spin-echo, single-shot turbo spin-echo, and 3D gradient-echo pulse sequences for the detection of pulmonary metastases. J Magn Reson Imaging 25:73–81PubMedCrossRef
21.
go back to reference Fabel M, Wintersperger BJ, Dietrich O, Eichinger M, Fink C, Puderbach M, Kauczor H-U, Schoenberg SO, Biederer J (2009) MRI of respiratory dynamics with 2D steady-state free-precession and 2D gradient echo sequences at 1.5 and 3 Tesla: an observer preference study. Eur Radiol 19:391–9PubMedCrossRef Fabel M, Wintersperger BJ, Dietrich O, Eichinger M, Fink C, Puderbach M, Kauczor H-U, Schoenberg SO, Biederer J (2009) MRI of respiratory dynamics with 2D steady-state free-precession and 2D gradient echo sequences at 1.5 and 3 Tesla: an observer preference study. Eur Radiol 19:391–9PubMedCrossRef
22.
go back to reference Gamsu G, de Geer G, Cann C, Müller N, Brito A (1987) A preliminary study of MRI quantification of simulated calcified pulmonary nodules. Invest Radiol 22:853–858PubMedCrossRef Gamsu G, de Geer G, Cann C, Müller N, Brito A (1987) A preliminary study of MRI quantification of simulated calcified pulmonary nodules. Invest Radiol 22:853–858PubMedCrossRef
23.
go back to reference Regier M, Kandel S, Kaul MG, Hoffmann B, Ittrich H, Bansmann PM, Kemper J, Nolte-Ernsting C, Heller M et al (2007) Detection of small pulmonary nodules in high-field MR at 3 T: evaluation of different pulse sequences using porcine lung explants. Eur Radiol 17:1341–51PubMedCrossRef Regier M, Kandel S, Kaul MG, Hoffmann B, Ittrich H, Bansmann PM, Kemper J, Nolte-Ernsting C, Heller M et al (2007) Detection of small pulmonary nodules in high-field MR at 3 T: evaluation of different pulse sequences using porcine lung explants. Eur Radiol 17:1341–51PubMedCrossRef
24.
go back to reference Chung MH, Lee HG, Kwon SS, Park SH (2000) MR imaging of solitary pulmonary lesion: emphasis on tuberculomas and comparison with tumors. J Magn Reson Imaging 11:629–637PubMedCrossRef Chung MH, Lee HG, Kwon SS, Park SH (2000) MR imaging of solitary pulmonary lesion: emphasis on tuberculomas and comparison with tumors. J Magn Reson Imaging 11:629–637PubMedCrossRef
25.
go back to reference Kersjes W, Mayer E, Buchenroth M, Schunk K, Fouda N, Cagil H (1997) Diagnosis of pulmonary metastases with turbo-SE MR imaging. Eur Radiol 7:1190–1194PubMedCrossRef Kersjes W, Mayer E, Buchenroth M, Schunk K, Fouda N, Cagil H (1997) Diagnosis of pulmonary metastases with turbo-SE MR imaging. Eur Radiol 7:1190–1194PubMedCrossRef
26.
27.
go back to reference Baumann T, Ludwig U, Pache G, Gall C, Saueressig U, Fisch D, Stankovic Z, Bartholomae J-P, Honal Mua (2008) Detection of pulmonary nodules with move-during-scan magnetic resonance imaging using a free-breathing turbo inversion recovery magnitude sequence. Invest Radiol 43:359–367PubMedCrossRef Baumann T, Ludwig U, Pache G, Gall C, Saueressig U, Fisch D, Stankovic Z, Bartholomae J-P, Honal Mua (2008) Detection of pulmonary nodules with move-during-scan magnetic resonance imaging using a free-breathing turbo inversion recovery magnitude sequence. Invest Radiol 43:359–367PubMedCrossRef
28.
go back to reference Khalil AM, Carette MF, Cadranel JL, Mayaud CM, Akoun GM, Bigot JM (1994) Magnetic resonance imaging findings in pulmonary Kaposi’s sarcoma: a series of 10 cases. Eur Respir J 7:1285–1289PubMedCrossRef Khalil AM, Carette MF, Cadranel JL, Mayaud CM, Akoun GM, Bigot JM (1994) Magnetic resonance imaging findings in pulmonary Kaposi’s sarcoma: a series of 10 cases. Eur Respir J 7:1285–1289PubMedCrossRef
29.
go back to reference Semelka RC, Cem Balci N, Wilber KP, Fisher LL, Brown MA, Gomez-Caminero A, Molina PL (2000) Breath-hold 3D gradient-echo MR imaging of the lung parenchyma: evaluation of reproducibility of image quality in normals and preliminary observations in patients with disease. J Magn Reson Imaging 11:195–200PubMedCrossRef Semelka RC, Cem Balci N, Wilber KP, Fisher LL, Brown MA, Gomez-Caminero A, Molina PL (2000) Breath-hold 3D gradient-echo MR imaging of the lung parenchyma: evaluation of reproducibility of image quality in normals and preliminary observations in patients with disease. J Magn Reson Imaging 11:195–200PubMedCrossRef
30.
go back to reference Biederer J, Both M, Graessner J, Liess C, Jakob P, Reuter M, Heller M (2003) Lung morphology: fast MR imaging assessment with a volumetric interpolated breath-hold technique: initial experience with patients. Radiology 226:242–9PubMedCrossRef Biederer J, Both M, Graessner J, Liess C, Jakob P, Reuter M, Heller M (2003) Lung morphology: fast MR imaging assessment with a volumetric interpolated breath-hold technique: initial experience with patients. Radiology 226:242–9PubMedCrossRef
31.
go back to reference Chen W, Jian W, H-tao L, Li C, Y-ke Z, Xie B, D-quan Z, Y-ming D, Lin Yua (2010) Whole-body diffusion-weighted imaging vs. FDG-PET for the detection of non-small-cell lung cancer. How do they measure up? Magn Reson Imaging 28:613–620PubMedCrossRef Chen W, Jian W, H-tao L, Li C, Y-ke Z, Xie B, D-quan Z, Y-ming D, Lin Yua (2010) Whole-body diffusion-weighted imaging vs. FDG-PET for the detection of non-small-cell lung cancer. How do they measure up? Magn Reson Imaging 28:613–620PubMedCrossRef
32.
go back to reference Yi CA, Shin KM, Lee KS, Kim B-T, Kim H, Kwon OJ, Choi JY, Chung MJ (2008) Non-small cell lung cancer staging: efficacy comparison of integrated PET/CT versus 3.0-T whole-body MR imaging. Radiology 248:632–642PubMedCrossRef Yi CA, Shin KM, Lee KS, Kim B-T, Kim H, Kwon OJ, Choi JY, Chung MJ (2008) Non-small cell lung cancer staging: efficacy comparison of integrated PET/CT versus 3.0-T whole-body MR imaging. Radiology 248:632–642PubMedCrossRef
33.
go back to reference Hasegawa I, Boiselle PM, Kuwabara K, Sawafuji M, Sugiura H (2008) Mediastinal lymph nodes in patients with non-small cell lung cancer: preliminary experience with diffusion-weighted MR imaging. J Thorac Imaging 23:157–161PubMedCrossRef Hasegawa I, Boiselle PM, Kuwabara K, Sawafuji M, Sugiura H (2008) Mediastinal lymph nodes in patients with non-small cell lung cancer: preliminary experience with diffusion-weighted MR imaging. J Thorac Imaging 23:157–161PubMedCrossRef
34.
go back to reference Pauls S, Schmidt SA, Juchems MS, Klass O, Luster M, Reske SN, Brambs H-J, Feuerlein S (2012) Diffusion-weighted MR imaging in comparison to integrated [(18)F]-FDG PET/CT for N-staging in patients with lung cancer. Eur J Radiol 81:178–182PubMedCrossRef Pauls S, Schmidt SA, Juchems MS, Klass O, Luster M, Reske SN, Brambs H-J, Feuerlein S (2012) Diffusion-weighted MR imaging in comparison to integrated [(18)F]-FDG PET/CT for N-staging in patients with lung cancer. Eur J Radiol 81:178–182PubMedCrossRef
35.
go back to reference Koyama H, Ohno Y, Aoyama N, Onishi Y, Matsumoto K, Nogami M, Takenaka D, Nishio W, Ohbayashi C et al (2010) Comparison of STIR turbo SE imaging and diffusion-weighted imaging of the lung: capability for detection and subtype classification of pulmonary adenocarcinomas. Eur Radiol 20:790–800PubMedCrossRef Koyama H, Ohno Y, Aoyama N, Onishi Y, Matsumoto K, Nogami M, Takenaka D, Nishio W, Ohbayashi C et al (2010) Comparison of STIR turbo SE imaging and diffusion-weighted imaging of the lung: capability for detection and subtype classification of pulmonary adenocarcinomas. Eur Radiol 20:790–800PubMedCrossRef
36.
go back to reference Liu H, Liu Y, Yu T, Ye N (2010) Usefulness of diffusion-weighted MR imaging in the evaluation of pulmonary lesions. Eur Radiol 20:807–815PubMedCrossRef Liu H, Liu Y, Yu T, Ye N (2010) Usefulness of diffusion-weighted MR imaging in the evaluation of pulmonary lesions. Eur Radiol 20:807–815PubMedCrossRef
37.
go back to reference Tondo F, Saponaro A, Stecco A, Lombardi M, Casadio C, Carriero A (2011) Role of diffusion-weighted imaging in the differential diagnosis of benign and malignant lesions of the chest-mediastinum. Radiol Med 116:720–733PubMedCrossRef Tondo F, Saponaro A, Stecco A, Lombardi M, Casadio C, Carriero A (2011) Role of diffusion-weighted imaging in the differential diagnosis of benign and malignant lesions of the chest-mediastinum. Radiol Med 116:720–733PubMedCrossRef
38.
go back to reference Kanauchi N, Oizumi H, Honma T, Kato H, Endo M, Suzuki J, Fukaya K, Sadahiro M (2009) Role of diffusion-weighted magnetic resonance imaging for predicting of tumor invasiveness for clinical stage IA non-small cell lung cancer. Eur J Cardiothorac Surg 35:706-710; discussion 710–711PubMedCrossRef Kanauchi N, Oizumi H, Honma T, Kato H, Endo M, Suzuki J, Fukaya K, Sadahiro M (2009) Role of diffusion-weighted magnetic resonance imaging for predicting of tumor invasiveness for clinical stage IA non-small cell lung cancer. Eur J Cardiothorac Surg 35:706-710; discussion 710–711PubMedCrossRef
39.
go back to reference Qi LP, Zhang XP, Tang L, Li J, Sun YS, Zhu GY (2009) Using diffusion-weighted MR imaging for tumor detection in the collapsed lung: a preliminary study. Eur Radiol 19:333–341PubMedCrossRef Qi LP, Zhang XP, Tang L, Li J, Sun YS, Zhu GY (2009) Using diffusion-weighted MR imaging for tumor detection in the collapsed lung: a preliminary study. Eur Radiol 19:333–341PubMedCrossRef
40.
go back to reference Uto T, Takehara Y, Nakamura Y, Naito T, Hashimoto D, Inui N, Suda T, Nakamura H, Chida K (2009) Higher sensitivity and specificity for diffusion-weighted imaging of malignant lung lesions without apparent diffusion coefficient quantification. Radiology 252:247–254PubMedCrossRef Uto T, Takehara Y, Nakamura Y, Naito T, Hashimoto D, Inui N, Suda T, Nakamura H, Chida K (2009) Higher sensitivity and specificity for diffusion-weighted imaging of malignant lung lesions without apparent diffusion coefficient quantification. Radiology 252:247–254PubMedCrossRef
41.
go back to reference Karabulut N (2009) Accuracy of diffusion-weighted MR imaging for differentiation of pulmonary lesions. Radiology 253:899; author reply 899–900PubMedCrossRef Karabulut N (2009) Accuracy of diffusion-weighted MR imaging for differentiation of pulmonary lesions. Radiology 253:899; author reply 899–900PubMedCrossRef
42.
go back to reference Henzler T, Schmid-Bindert G, Schoenberg SO, Fink C (2010) Diffusion and perfusion MRI of the lung and mediastinum. Eur J Radiol 76:329–336PubMedCrossRef Henzler T, Schmid-Bindert G, Schoenberg SO, Fink C (2010) Diffusion and perfusion MRI of the lung and mediastinum. Eur J Radiol 76:329–336PubMedCrossRef
43.
go back to reference Regier M, Schwarz D, Henes FO, Groth M, Kooijman H, Begemann PG, Adam G (2011) Diffusion-weighted MR-imaging for the detection of pulmonary nodules at 1.5 Tesla: intraindividual comparison with multidetector computed tomography. J Med Imaging Radiat Oncol 55:266–274PubMedCrossRef Regier M, Schwarz D, Henes FO, Groth M, Kooijman H, Begemann PG, Adam G (2011) Diffusion-weighted MR-imaging for the detection of pulmonary nodules at 1.5 Tesla: intraindividual comparison with multidetector computed tomography. J Med Imaging Radiat Oncol 55:266–274PubMedCrossRef
45.
go back to reference Kluge A, Müller C, Hansel J, Gerriets T, Bachmann G (2004) Real-time MR with TrueFISP for the detection of acute pulmonary embolism: initial clinical experience. Eur Radiol 14:709–718PubMedCrossRef Kluge A, Müller C, Hansel J, Gerriets T, Bachmann G (2004) Real-time MR with TrueFISP for the detection of acute pulmonary embolism: initial clinical experience. Eur Radiol 14:709–718PubMedCrossRef
46.
go back to reference Kluge A, Gerriets T, Stolz E, Dill T, Mueller K-D, Mueller C, Bachmann G (2006) Pulmonary perfusion in acute pulmonary embolism: agreement of MRI and SPECT for lobar, segmental and subsegmental perfusion defects. Acta Radiol 47:933–940PubMedCrossRef Kluge A, Gerriets T, Stolz E, Dill T, Mueller K-D, Mueller C, Bachmann G (2006) Pulmonary perfusion in acute pulmonary embolism: agreement of MRI and SPECT for lobar, segmental and subsegmental perfusion defects. Acta Radiol 47:933–940PubMedCrossRef
47.
go back to reference Kluge A, Gerriets T, Müller C, Ekinci O, Neumann T, Dill T, Bachmann G (2005) Thoracic real-time MRI: experience from 2200 examinations in acute and ill-defined thoracic diseases. Rofo 177:1513–1521PubMedCrossRef Kluge A, Gerriets T, Müller C, Ekinci O, Neumann T, Dill T, Bachmann G (2005) Thoracic real-time MRI: experience from 2200 examinations in acute and ill-defined thoracic diseases. Rofo 177:1513–1521PubMedCrossRef
48.
go back to reference Moody AR, Liddicoat A, Krarup K (1997) Magnetic resonance pulmonary angiography and direct imaging of embolus for the detection of pulmonary emboli. Invest Radiol 32:431–440PubMedCrossRef Moody AR, Liddicoat A, Krarup K (1997) Magnetic resonance pulmonary angiography and direct imaging of embolus for the detection of pulmonary emboli. Invest Radiol 32:431–440PubMedCrossRef
49.
50.
go back to reference Biederer J, Liess C, Charalambous N, Heller M (2004) Volumetric interpolated contrast-enhanced MRA for the diagnosis of pulmonary embolism in an ex vivo system. J Magn Reson Imaging 19:428–37PubMedCrossRef Biederer J, Liess C, Charalambous N, Heller M (2004) Volumetric interpolated contrast-enhanced MRA for the diagnosis of pulmonary embolism in an ex vivo system. J Magn Reson Imaging 19:428–37PubMedCrossRef
51.
go back to reference Matsuoka S, Uchiyama K, Shima H, Terakoshi H, Oishi S, Nojiri Y, Ogata H (2002) Effect of the rate of gadolinium injection on magnetic resonance pulmonary perfusion imaging. J Magn Reson Imaging 15:108–113PubMedCrossRef Matsuoka S, Uchiyama K, Shima H, Terakoshi H, Oishi S, Nojiri Y, Ogata H (2002) Effect of the rate of gadolinium injection on magnetic resonance pulmonary perfusion imaging. J Magn Reson Imaging 15:108–113PubMedCrossRef
52.
go back to reference Meaney JF, Weg JG, Chenevert TL, Stafford-Johnson D, Hamilton BH, Prince MR (1997) Diagnosis of pulmonary embolism with magnetic resonance angiography. N Engl J Med 336:1422–1427PubMedCrossRef Meaney JF, Weg JG, Chenevert TL, Stafford-Johnson D, Hamilton BH, Prince MR (1997) Diagnosis of pulmonary embolism with magnetic resonance angiography. N Engl J Med 336:1422–1427PubMedCrossRef
53.
go back to reference Gupta A, Frazer CK, Ferguson JM, Kumar AB, Davis SJ, Fallon MJ, Morris IT, Drury PJ, Cala LA (1999) Acute pulmonary embolism: diagnosis with MR angiography. Radiology 210:353–359PubMedCrossRef Gupta A, Frazer CK, Ferguson JM, Kumar AB, Davis SJ, Fallon MJ, Morris IT, Drury PJ, Cala LA (1999) Acute pulmonary embolism: diagnosis with MR angiography. Radiology 210:353–359PubMedCrossRef
54.
go back to reference Oudkerk M, van Beek EJR, Wielopolski P, van Ooijen PMA, Brouwers-Kuyper EMJ, Bongaerts AHH, Berghout A (2002) Comparison of contrast-enhanced magnetic resonance angiography and conventional pulmonary angiography for the diagnosis of pulmonary embolism: a prospective study. Lancet 359:1643–1647PubMedCrossRef Oudkerk M, van Beek EJR, Wielopolski P, van Ooijen PMA, Brouwers-Kuyper EMJ, Bongaerts AHH, Berghout A (2002) Comparison of contrast-enhanced magnetic resonance angiography and conventional pulmonary angiography for the diagnosis of pulmonary embolism: a prospective study. Lancet 359:1643–1647PubMedCrossRef
55.
go back to reference Goyen M, Laub G, Ladd ME, Debatin JF, Barkhausen J, Truemmler KH, Bosk S, Ruehm SG (2001) Dynamic 3D MR angiography of the pulmonary arteries in under four seconds. J Magn Reson Imaging 13:372–377PubMedCrossRef Goyen M, Laub G, Ladd ME, Debatin JF, Barkhausen J, Truemmler KH, Bosk S, Ruehm SG (2001) Dynamic 3D MR angiography of the pulmonary arteries in under four seconds. J Magn Reson Imaging 13:372–377PubMedCrossRef
56.
go back to reference Stein PD, Chenevert TL, Fowler SE, Goodman LR, Gottschalk A, Hales CA, Hull RD, Jablonski KA, Leeper KV et al (2010) Gadolinium-enhanced magnetic resonance angiography for pulmonary embolism: a multicenter prospective study (PIOPED III). Ann Intern Med 152:434-443, W142-W143PubMedPubMedCentralCrossRef Stein PD, Chenevert TL, Fowler SE, Goodman LR, Gottschalk A, Hales CA, Hull RD, Jablonski KA, Leeper KV et al (2010) Gadolinium-enhanced magnetic resonance angiography for pulmonary embolism: a multicenter prospective study (PIOPED III). Ann Intern Med 152:434-443, W142-W143PubMedPubMedCentralCrossRef
57.
go back to reference Eichinger M, Puderbach M, Fink C, Gahr J, Ley S, Plathow C, Tuengerthal S, Zuna I, Müller F-M et al (2006) Contrast-enhanced 3D MRI of lung perfusion in children with cystic fibrosis--initial results. Eur Radiol 16:2147–52PubMedCrossRef Eichinger M, Puderbach M, Fink C, Gahr J, Ley S, Plathow C, Tuengerthal S, Zuna I, Müller F-M et al (2006) Contrast-enhanced 3D MRI of lung perfusion in children with cystic fibrosis--initial results. Eur Radiol 16:2147–52PubMedCrossRef
58.
go back to reference Ersoy H, Goldhaber SZ, Cai T, Luu T, Rosebrook J, Mulkern R, Rybicki F (2007) Time-resolved MR angiography: a primary screening examination of patients with suspected pulmonary embolism and contraindications to administration of iodinated contrast material. AJR Am J Roentgenol 188:1246–1254PubMedCrossRef Ersoy H, Goldhaber SZ, Cai T, Luu T, Rosebrook J, Mulkern R, Rybicki F (2007) Time-resolved MR angiography: a primary screening examination of patients with suspected pulmonary embolism and contraindications to administration of iodinated contrast material. AJR Am J Roentgenol 188:1246–1254PubMedCrossRef
59.
go back to reference Levin DL, Chen Q, Zhang M, Edelman RR, Hatabu H (2001) Evaluation of regional pulmonary perfusion using ultrafast magnetic resonance imaging. Magn Reson Med 46:166–171PubMedCrossRef Levin DL, Chen Q, Zhang M, Edelman RR, Hatabu H (2001) Evaluation of regional pulmonary perfusion using ultrafast magnetic resonance imaging. Magn Reson Med 46:166–171PubMedCrossRef
60.
go back to reference Arai TJ, Henderson AC, Dubowitz DJ, Levin DL, Friedman PJ, Buxton RB, Prisk GK, Hopkins SR (2009) Hypoxic pulmonary vasoconstriction does not contribute to pulmonary blood flow heterogeneity in normoxia in normal supine humans. J Appl Physiol 106:1057–1064PubMedCrossRef Arai TJ, Henderson AC, Dubowitz DJ, Levin DL, Friedman PJ, Buxton RB, Prisk GK, Hopkins SR (2009) Hypoxic pulmonary vasoconstriction does not contribute to pulmonary blood flow heterogeneity in normoxia in normal supine humans. J Appl Physiol 106:1057–1064PubMedCrossRef
61.
go back to reference Burnham KJ, Arai TJ, Dubowitz DJ, Henderson AC, Holverda S, Buxton RB, Prisk GK, Hopkins SR (2009) Pulmonary perfusion heterogeneity is increased by sustained, heavy exercise in humans. J Appl Physiol 107:1559–1568PubMedPubMedCentralCrossRef Burnham KJ, Arai TJ, Dubowitz DJ, Henderson AC, Holverda S, Buxton RB, Prisk GK, Hopkins SR (2009) Pulmonary perfusion heterogeneity is increased by sustained, heavy exercise in humans. J Appl Physiol 107:1559–1568PubMedPubMedCentralCrossRef
62.
go back to reference Eichinger M, Puderbach M, Fink C, Gahr J, Ley S, Plathow C, Tuengerthal S, Zuna I, Müller F-M et al (2006) Contrast-enhanced 3D MRI of lung perfusion in children with cystic fibrosis--initial results. Eur Radiol 16:2147–52PubMedCrossRef Eichinger M, Puderbach M, Fink C, Gahr J, Ley S, Plathow C, Tuengerthal S, Zuna I, Müller F-M et al (2006) Contrast-enhanced 3D MRI of lung perfusion in children with cystic fibrosis--initial results. Eur Radiol 16:2147–52PubMedCrossRef
63.
go back to reference Altes TA, Eichinger M, Puderbach M (2007) Magnetic resonance imaging of the lung in cystic fibrosis. Proc Am Thorac Soc 4:321–327PubMedCrossRef Altes TA, Eichinger M, Puderbach M (2007) Magnetic resonance imaging of the lung in cystic fibrosis. Proc Am Thorac Soc 4:321–327PubMedCrossRef
64.
go back to reference Eichinger M, Optazaite D-E, Kopp-Schneider A, Hintze C, Biederer J, Niemann A, Mall MA, Wielpütz MO, Kauczor H-U et al (2011) Morphologic and functional scoring of cystic fibrosis lung disease using MRI. Eur J Radiol (in press) Eichinger M, Optazaite D-E, Kopp-Schneider A, Hintze C, Biederer J, Niemann A, Mall MA, Wielpütz MO, Kauczor H-U et al (2011) Morphologic and functional scoring of cystic fibrosis lung disease using MRI. Eur J Radiol (in press)
65.
go back to reference Puderbach M, Eichinger M, Haeselbarth J, Ley S, Kopp-Schneider A, Tuengerthal S, Schmaehl A, Fink C, Plathow C et al (2007) Assessment of morphological MRI for pulmonary changes in cystic fibrosis (CF) patients: comparison to thin-section CT and chest x-ray. Invest Radiol 42:715–725PubMedCrossRef Puderbach M, Eichinger M, Haeselbarth J, Ley S, Kopp-Schneider A, Tuengerthal S, Schmaehl A, Fink C, Plathow C et al (2007) Assessment of morphological MRI for pulmonary changes in cystic fibrosis (CF) patients: comparison to thin-section CT and chest x-ray. Invest Radiol 42:715–725PubMedCrossRef
66.
go back to reference Puderbach M, Eichinger M, Gahr J, Ley S, Tuengerthal S, Schmähl A, Fink C, Plathow C, Wiebel M et al (2007) Proton MRI appearance of cystic fibrosis: comparison to CT. Eur Radiol 17:716–724PubMedCrossRef Puderbach M, Eichinger M, Gahr J, Ley S, Tuengerthal S, Schmähl A, Fink C, Plathow C, Wiebel M et al (2007) Proton MRI appearance of cystic fibrosis: comparison to CT. Eur Radiol 17:716–724PubMedCrossRef
67.
go back to reference Biederer J, Reuter M, Both M, Muhle C, Grimm J, Graessner J, Heller M (2002) Analysis of artefacts and detail resolution of lung MRI with breath-hold T1-weighted gradient-echo and T2-weighted fast spin-echo sequences with respiratory triggering. Eur Radiol 12:378–384PubMedCrossRef Biederer J, Reuter M, Both M, Muhle C, Grimm J, Graessner J, Heller M (2002) Analysis of artefacts and detail resolution of lung MRI with breath-hold T1-weighted gradient-echo and T2-weighted fast spin-echo sequences with respiratory triggering. Eur Radiol 12:378–384PubMedCrossRef
68.
go back to reference Fabel M, Wintersperger BJ, Dietrich O, Eichinger M, Fink C, Puderbach M, Kauczor H-U, Schoenberg SO, Biederer J (2009) MRI of respiratory dynamics with 2D steady-state free-precession and 2D gradient echo sequences at 1.5 and 3 Tesla: an observer preference study. Eur Radiol 19:391–9PubMedCrossRef Fabel M, Wintersperger BJ, Dietrich O, Eichinger M, Fink C, Puderbach M, Kauczor H-U, Schoenberg SO, Biederer J (2009) MRI of respiratory dynamics with 2D steady-state free-precession and 2D gradient echo sequences at 1.5 and 3 Tesla: an observer preference study. Eur Radiol 19:391–9PubMedCrossRef
69.
go back to reference Biederer J, Dinkel J, Bolte H, Welzel T, Hoffmann B, Thierfelder C, Mende U, Debus J, Heller M et al (2007) Respiratory-gated helical computed tomography of lung: reproducibility of small volumes in an ex vivo model. Int J Radiat Oncol Biol Phys 69:1642–9PubMedCrossRef Biederer J, Dinkel J, Bolte H, Welzel T, Hoffmann B, Thierfelder C, Mende U, Debus J, Heller M et al (2007) Respiratory-gated helical computed tomography of lung: reproducibility of small volumes in an ex vivo model. Int J Radiat Oncol Biol Phys 69:1642–9PubMedCrossRef
70.
go back to reference Cai J, Read PW, Altes TA, Molloy JA, Brookeman JR, Sheng K (2007) Evaluation of the reproducibility of lung motion probability distribution function (PDF) using dynamic MRI. Phys Med Biol 52:365–373PubMedCrossRef Cai J, Read PW, Altes TA, Molloy JA, Brookeman JR, Sheng K (2007) Evaluation of the reproducibility of lung motion probability distribution function (PDF) using dynamic MRI. Phys Med Biol 52:365–373PubMedCrossRef
71.
go back to reference Adamson J, Chang Z, Wang Z, Yin F-F, Cai J (2010) Maximum intensity projection (MIP) imaging using slice-stacking MRI. Med Phys 37:5914–5920PubMedCrossRef Adamson J, Chang Z, Wang Z, Yin F-F, Cai J (2010) Maximum intensity projection (MIP) imaging using slice-stacking MRI. Med Phys 37:5914–5920PubMedCrossRef
72.
go back to reference Tetzlaff R, Schwarz T, Kauczor H-U, Meinzer H-P, Puderbach M, Eichinger M (2010) Lung function measurement of single lungs by lung area segmentation on 2D dynamic MRI. Acad Radiol 17:496–503PubMedCrossRef Tetzlaff R, Schwarz T, Kauczor H-U, Meinzer H-P, Puderbach M, Eichinger M (2010) Lung function measurement of single lungs by lung area segmentation on 2D dynamic MRI. Acad Radiol 17:496–503PubMedCrossRef
73.
go back to reference Wild JM, Schmiedeskamp J, Paley MNJ, Filbir F, Fichele S, Kasuboski L, Knitz F, Woodhouse N, Swift A et al (2002) MR imaging of the lungs with hyperpolarized helium-3 gas transported by air. Phys Med Biol 47:N185–N190PubMedCrossRef Wild JM, Schmiedeskamp J, Paley MNJ, Filbir F, Fichele S, Kasuboski L, Knitz F, Woodhouse N, Swift A et al (2002) MR imaging of the lungs with hyperpolarized helium-3 gas transported by air. Phys Med Biol 47:N185–N190PubMedCrossRef
74.
go back to reference Scholz A-W, Wolf U, Fabel M, Weiler N, Heussel CP, Eberle B, David M, Schreiber WG (2009) Comparison of magnetic resonance imaging of inhaled SF6 with respiratory gas analysis. Magn Reson Imaging 27:549–556PubMedCrossRef Scholz A-W, Wolf U, Fabel M, Weiler N, Heussel CP, Eberle B, David M, Schreiber WG (2009) Comparison of magnetic resonance imaging of inhaled SF6 with respiratory gas analysis. Magn Reson Imaging 27:549–556PubMedCrossRef
75.
go back to reference Molinari F, Puderbach M, Eichinger M, Ley S, Fink C, Bonomo L, Kauczor H-U, Bock M (2008) Oxygen-enhanced magnetic resonance imaging: influence of different gas delivery methods on the T1-changes of the lungs. Invest Radiol 43:427–432PubMedCrossRef Molinari F, Puderbach M, Eichinger M, Ley S, Fink C, Bonomo L, Kauczor H-U, Bock M (2008) Oxygen-enhanced magnetic resonance imaging: influence of different gas delivery methods on the T1-changes of the lungs. Invest Radiol 43:427–432PubMedCrossRef
76.
go back to reference Suga K, Ogasawara N, Tsukuda T, Matsunaga N (2002) Assessment of regional lung ventilation in dog lungs with Gd-DTPA aerosol ventilation MR imaging. Acta Radiol 43:282–291PubMedCrossRef Suga K, Ogasawara N, Tsukuda T, Matsunaga N (2002) Assessment of regional lung ventilation in dog lungs with Gd-DTPA aerosol ventilation MR imaging. Acta Radiol 43:282–291PubMedCrossRef
77.
go back to reference Attenberger UI, Ingrisch M, Dietrich O, Herrmann K, Nikolaou K, Reiser MF, Schönberg SO, Fink C (2009) Time-resolved 3D pulmonary perfusion MRI: comparison of different k-space acquisition strategies at 1.5 and 3 T. Invest Radiol 44:525–531PubMedCrossRef Attenberger UI, Ingrisch M, Dietrich O, Herrmann K, Nikolaou K, Reiser MF, Schönberg SO, Fink C (2009) Time-resolved 3D pulmonary perfusion MRI: comparison of different k-space acquisition strategies at 1.5 and 3 T. Invest Radiol 44:525–531PubMedCrossRef
78.
go back to reference Peltola V, Ruuskanen O, Svedström E (2008) Magnetic resonance imaging of lung infections in children. Pediatr Radiol 38:1225–1231PubMedCrossRef Peltola V, Ruuskanen O, Svedström E (2008) Magnetic resonance imaging of lung infections in children. Pediatr Radiol 38:1225–1231PubMedCrossRef
79.
go back to reference Ley-Zaporozhan J, Ley S, Sommerburg O, Komm N, Müller F-MC, Schenk JP (2009) Clinical application of MRI in children for the assessment of pulmonary diseases. Rofo 181:419–432PubMedCrossRef Ley-Zaporozhan J, Ley S, Sommerburg O, Komm N, Müller F-MC, Schenk JP (2009) Clinical application of MRI in children for the assessment of pulmonary diseases. Rofo 181:419–432PubMedCrossRef
80.
go back to reference Failo R, Wielopolski PA, Tiddens HAWM, Hop WCJ, Mucelli RP, Lequin MH (2009) Lung morphology assessment using MRI: a robust ultra-short TR/TE 2D steady state free precession sequence used in cystic fibrosis patients. Magn Reson Med 61:299–306PubMedCrossRef Failo R, Wielopolski PA, Tiddens HAWM, Hop WCJ, Mucelli RP, Lequin MH (2009) Lung morphology assessment using MRI: a robust ultra-short TR/TE 2D steady state free precession sequence used in cystic fibrosis patients. Magn Reson Med 61:299–306PubMedCrossRef
81.
go back to reference Wagner M, Böwing B, Kuth R, Deimling M, Rascher W, Rupprecht T (2001) Low field thoracic MRI–a fast and radiation free routine imaging modality in children. Magn Reson Imaging 19:975–983PubMedCrossRef Wagner M, Böwing B, Kuth R, Deimling M, Rascher W, Rupprecht T (2001) Low field thoracic MRI–a fast and radiation free routine imaging modality in children. Magn Reson Imaging 19:975–983PubMedCrossRef
82.
go back to reference Rupprecht T, Kuth R, Bowing B, Gerling S, Wagner M, Rascher W (2000) Sedation and monitoring of paediatric patients undergoing open low-field MRI. Acta Paediatr 89:1077–1081PubMed Rupprecht T, Kuth R, Bowing B, Gerling S, Wagner M, Rascher W (2000) Sedation and monitoring of paediatric patients undergoing open low-field MRI. Acta Paediatr 89:1077–1081PubMed
83.
go back to reference Serra G, Milito C, Mitrevski M, Granata G, Martini H, Pesce AM, Sfika I, Bonanni L, Catalano C et al (2011) Lung MRI as a possible alternative to CT scan for patients with primary immune deficiencies and increased radio sensitivity. Chest 140:1581–1589PubMedCrossRef Serra G, Milito C, Mitrevski M, Granata G, Martini H, Pesce AM, Sfika I, Bonanni L, Catalano C et al (2011) Lung MRI as a possible alternative to CT scan for patients with primary immune deficiencies and increased radio sensitivity. Chest 140:1581–1589PubMedCrossRef
84.
go back to reference Hirsch W, Sorge I, Krohmer S, Weber D, Meier K, Till H (2008) MRI of the lungs in children. Eur J Radiol 68:278–288PubMedCrossRef Hirsch W, Sorge I, Krohmer S, Weber D, Meier K, Till H (2008) MRI of the lungs in children. Eur J Radiol 68:278–288PubMedCrossRef
85.
86.
go back to reference Sanborn PA, Michna E, Zurakowski D, Burrows PE, Fontaine PJ, Connor L, Mason KP (2005) Adverse cardiovascular and respiratory events during sedation of pediatric patients for imaging examinations. Radiology 237:288–294PubMedCrossRef Sanborn PA, Michna E, Zurakowski D, Burrows PE, Fontaine PJ, Connor L, Mason KP (2005) Adverse cardiovascular and respiratory events during sedation of pediatric patients for imaging examinations. Radiology 237:288–294PubMedCrossRef
87.
go back to reference Lutterbey G, Wattjes MP, Doerr D, Fischer NJ, Gieseke J Jr, Schild HH (2007) Atelectasis in children undergoing either propofol infusion or positive pressure ventilation anesthesia for magnetic resonance imaging. Paediatr Anaesth 17:121–125PubMedCrossRef Lutterbey G, Wattjes MP, Doerr D, Fischer NJ, Gieseke J Jr, Schild HH (2007) Atelectasis in children undergoing either propofol infusion or positive pressure ventilation anesthesia for magnetic resonance imaging. Paediatr Anaesth 17:121–125PubMedCrossRef
88.
go back to reference Biederer J (2009) General requirements of MRI of the lung and suggested standard protocol. In: Kauczor H-U (ed) MRI of the lung. Springer, Berlin Heidelberg, pp 3–16 Biederer J (2009) General requirements of MRI of the lung and suggested standard protocol. In: Kauczor H-U (ed) MRI of the lung. Springer, Berlin Heidelberg, pp 3–16
89.
go back to reference Biederer J, Puderbach M (2009) MR imaging of the chest. HIRE 3:39–42 Biederer J, Puderbach M (2009) MR imaging of the chest. HIRE 3:39–42
90.
go back to reference Puderbach M, Hintze C, Ley S, Eichinger M, Kauczor H-U, Biederer J (2007) MR imaging of the chest: a practical approach at 1.5 T. Eur J Radiol 64:345–55PubMedCrossRef Puderbach M, Hintze C, Ley S, Eichinger M, Kauczor H-U, Biederer J (2007) MR imaging of the chest: a practical approach at 1.5 T. Eur J Radiol 64:345–55PubMedCrossRef
91.
go back to reference Hintze C, Biederer J, Kauczor H-U (2007) Magnetic resonance imaging of the chest. In: Magnevist Monograph. Springer, Berlin, Heidelberg, New York, pp 87–103 Hintze C, Biederer J, Kauczor H-U (2007) Magnetic resonance imaging of the chest. In: Magnevist Monograph. Springer, Berlin, Heidelberg, New York, pp 87–103
93.
go back to reference Stein PD, Gottschalk A, Sostman HD, Chenevert TL, Fowler SE, Goodman LR, Hales CA, Hull RD, Kanal E et al (2008) Methods of prospective investigation of pulmonary embolism diagnosis III (PIOPED III). Semin Nucl Med 38:462–470 Stein PD, Gottschalk A, Sostman HD, Chenevert TL, Fowler SE, Goodman LR, Hales CA, Hull RD, Kanal E et al (2008) Methods of prospective investigation of pulmonary embolism diagnosis III (PIOPED III). Semin Nucl Med 38:462–470
94.
go back to reference Kluge A, Luboldt W, Bachmann G (2006) Acute pulmonary embolism to the subsegmental level: diagnostic accuracy of three MRI techniques compared with 16-MDCT. AJR Am J Roentgenol 187:W7–W14PubMedCrossRef Kluge A, Luboldt W, Bachmann G (2006) Acute pulmonary embolism to the subsegmental level: diagnostic accuracy of three MRI techniques compared with 16-MDCT. AJR Am J Roentgenol 187:W7–W14PubMedCrossRef
Metadata
Title
MRI of the lung (2/3). Why … when … how?
Authors
J. Biederer
M. Beer
W. Hirsch
J. Wild
M. Fabel
M. Puderbach
E. J. R. Van Beek
Publication date
01-08-2012
Publisher
Springer Berlin Heidelberg
Published in
Insights into Imaging / Issue 4/2012
Electronic ISSN: 1869-4101
DOI
https://doi.org/10.1007/s13244-011-0146-8

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