Primary Choriocarcinoma of the Stomach. A Case Report and Review of the Literature

Excerpt

Choriocarcinoma is a β –HCG secreting tumour which develops from trophoblastic or totipotent germ cells primarily in ovary and testis, however it can also occur rarely in extra gonadal sites like mediastinum, retroperitoneum, pineal gland, liver, gallbladder, urinary tract system etc. [1]. Choriocarcinoma can also develop from the stomach very rarely and only few cases have been reported in the literature so far [2]. Moreover, around 70 % of gastric choriocarcinomas show some adenocarcinoma components along with it [3‐5] and making pure choriocarcinoma of stomach a rare entity. Unlike adenocarcinoma of stomach, it is difficult to diagnose PGC by endoscopic biopsy and only 8 to 15 % cases are diagnosed by it. Most cases reported were diagnosed after surgery. Here, we report a case of 60 year old female with locally advanced pure form of PGC diagnosed by endoscopic biopsy. …