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Published in: Nuclear Medicine and Molecular Imaging 4/2017

Open Access 01-12-2017 | Interesting Image

68Ga-PSMA PET-CT Imaging of Metastatic Adenoid Cystic Carcinoma

Authors: Bart de Keizer, Gerard C. Krijger, F. Tessa Ververs, Robert J. J. van Es, Remco de Bree, Stefan Willems

Published in: Nuclear Medicine and Molecular Imaging | Issue 4/2017

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Abstract

A patient with a history of adenoid cystic carcinoma of the nasal cavity presented himself with bone pain and an elevated PSA level. On suspicion of metastatic prostate cancer a 68Ga-PSMA PET-CT was performed. The PET-CT showed numerous lung and non-sclerotic bone metastasis. Biopsy of a bone metastasis was performed and pathology showed adenoid cystic carcinoma instead of prostate cancer. Immunohistochemical PSMA staining of the primary tumour showed intense PSMA expression in adenoid cystic carcinoma tumour cells. Because of the high PSMA expression of adenoid cystic carcinoma, 68Ga-PSMA PET-CT might be a promising imaging modality for this malignancy.
Metadata
Title
68Ga-PSMA PET-CT Imaging of Metastatic Adenoid Cystic Carcinoma
Authors
Bart de Keizer
Gerard C. Krijger
F. Tessa Ververs
Robert J. J. van Es
Remco de Bree
Stefan Willems
Publication date
01-12-2017
Publisher
Springer Berlin Heidelberg
Published in
Nuclear Medicine and Molecular Imaging / Issue 4/2017
Print ISSN: 1869-3474
Electronic ISSN: 1869-3482
DOI
https://doi.org/10.1007/s13139-016-0445-6

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