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Translational Stroke Research
Published in: Translational Stroke Research 6/2014

01-12-2014 | Original Article

Rat Endovascular Perforation Model

Author: Fatima A. Sehba

Published in: Translational Stroke Research | Issue 6/2014

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Abstract

Experimental animal models of aneurysmal subarachnoid hemorrhage (SAH) have provided a wealth of information on the mechanisms of brain injury. The rat endovascular perforation (EVP) model replicates the early pathophysiology of SAH and hence is frequently used to study early brain injury following SAH. This paper presents a brief review of historical development of the EVP model and details the technique used to create SAH and considerations necessary to overcome technical challenges.
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Metadata
Title
Rat Endovascular Perforation Model
Author
Fatima A. Sehba
Publication date
01-12-2014
Publisher
Springer US
Published in
Translational Stroke Research / Issue 6/2014
Print ISSN: 1868-4483
Electronic ISSN: 1868-601X
DOI
https://doi.org/10.1007/s12975-014-0368-4

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