A 48-year-old, otherwise healthy woman, with a new onset recurring chest pain over a period of 1 week was admitted for coronary angiography. Surprisingly, a tubular-shaped high-grade stenosis in the middle segment of the LAD (Fig. 1a and Video 1) was revealed, simultaneous with a clear dissection seen as a radiolucent lumen resembling a Type 1 spontaneous artery dissection (SCAD), extending from the middle part of the RCA to its distal segment (Fig. 2a). Filling of the distal part of the RCA through contralateral LAD collaterals as well as TIMI II flow at LAD, led to primary imaging-guided PCI of the LAD. Optical coherence tomography imaging (OCT) showed a dissection flap and concomitant intramural hematoma (Fig. 1b) attributing to Type 3 SCAD, which was treated by primary drug-eluting-stent implantation (Fig. 1c). During a follow-up appointment after 6 weeks, the patient still reported about recurring chest pain since the first intervention. Thus, staged PCI of the RCA was performed: the proximal dissected segment was crossed into the side branch using microcatheter support, followed by exchange to a double-lumen microcatheter, allowing the safe crossing to the distal RCA lumen by a Gaia-1 wire (after failed crossing using a floppy and then a Fielder XT-A wires) (Fig. 2b and Video 2). Long-segment drug-eluting-stent PCI was performed covering the dissected part completely (Fig. 2c).