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Published in: Journal of Maxillofacial and Oral Surgery 4/2016

01-12-2016 | Review Paper

Mandibular Reconstruction: Overview

Authors: Batchu Pavan Kumar, V. Venkatesh, K. A. Jeevan Kumar, B. Yashwanth Yadav, S. Ram Mohan

Published in: Journal of Maxillofacial and Oral Surgery | Issue 4/2016

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Abstract

Introduction

Mandibular reconstruction has changed significantly over the years and continues to evolve with the introduction of newer technologies and techniques.

Purpose

This article reviews the history of oromandibular reconstruction, biomechanics of mandible, summarizes the reconstruction options available for mandible with defect classification, goals in reconstruction, the various donor sites, current reconstructive options, dental rehabilitation and persistent associated problems.

Summary

Oromandibular reconstruction, although a challenge for the head and neck reconstructive surgeon, is now reliable and highly successful with excellent long-term functional and aesthetic outcomes with the use of autogenous bone grafts and current reconstructive options. The ideal reconstruction would provide a solid arch to articulate with the upper jaw, restoring swallowing speech, mastication, and esthetics. Autogenous vascularized bone grafts in combination with microsurgical techniques have revolutionized mandibular reconstruction in oral cancer surgery. Current trends in mandibular reconstruction aim to achieve reestablishment of a viable mandible of proper form and maxillary mandibular relationship while decreasing the need for invasive autogenous graft procurement. However the optimal reconstruction of mandibular defects is still controversial in regards to reconstructive options which include the donor site selection, timing of surgery and method of reconstruction.
Literature
1.
go back to reference Ivy RH (1951) Bone grafting for restoration of defects of the mandible. Plast Reconstr Surg (1946) 7(4):333–341CrossRef Ivy RH (1951) Bone grafting for restoration of defects of the mandible. Plast Reconstr Surg (1946) 7(4):333–341CrossRef
2.
go back to reference Tessier P, Kawamoto H, Matthews D, Posnick J, Raulo Y, Tulasne JF, Wolfe SA (2005) Taking long rib grafts for facial reconstruction: tools and techniques—III. A 2900-case experience in maxillofacial and craniofacial surgery. Plast Reconstr Surg 116(5 Suppl):38S–46S (discussion 92S–94S)PubMedCrossRef Tessier P, Kawamoto H, Matthews D, Posnick J, Raulo Y, Tulasne JF, Wolfe SA (2005) Taking long rib grafts for facial reconstruction: tools and techniques—III. A 2900-case experience in maxillofacial and craniofacial surgery. Plast Reconstr Surg 116(5 Suppl):38S–46S (discussion 92S–94S)PubMedCrossRef
3.
go back to reference Testelin S (1992) History of microsurgical reconstruction of the mandible. Ann Chir Plast Esthet 37(3):241–245PubMed Testelin S (1992) History of microsurgical reconstruction of the mandible. Ann Chir Plast Esthet 37(3):241–245PubMed
4.
go back to reference de Fries HO (1981) Reconstruction of the mandible: use of combined homologous mandible and autologous bone. Otolaryngol Head Neck Surg 89(4):694–697 de Fries HO (1981) Reconstruction of the mandible: use of combined homologous mandible and autologous bone. Otolaryngol Head Neck Surg 89(4):694–697
6.
go back to reference Lowlicht RA, Delacure MD, Sasaki CT (1990) Allogeneic (homograft) reconstruction of the mandible. Laryngoscope 100(8):837–843PubMedCrossRef Lowlicht RA, Delacure MD, Sasaki CT (1990) Allogeneic (homograft) reconstruction of the mandible. Laryngoscope 100(8):837–843PubMedCrossRef
7.
go back to reference Attie JN, Catania A, Ripstein CB (1953) Stainless steel mesh prosthesis for immediate replacement of hemimandibulectomy. Surgery 33:712PubMed Attie JN, Catania A, Ripstein CB (1953) Stainless steel mesh prosthesis for immediate replacement of hemimandibulectomy. Surgery 33:712PubMed
8.
go back to reference Blocker TC, Stout RA (1949) Mandibular reconstruction. World War II. Plast Reconstr Surg 4:153CrossRef Blocker TC, Stout RA (1949) Mandibular reconstruction. World War II. Plast Reconstr Surg 4:153CrossRef
9.
go back to reference Castermans A, Van Garse R, Vanwick R (1977) Primary resection of mandible after resection for oral cancer. Acta Chir Belg 2:205–208 Castermans A, Van Garse R, Vanwick R (1977) Primary resection of mandible after resection for oral cancer. Acta Chir Belg 2:205–208
11.
go back to reference Albert TW, Smith JD, Everts E, Cook TA (1980) Dacron mesh tray and cancellous bone in reconstruction of mandibular defects. Arch Otolaryngol Head Neck Surg 8:78–83 Albert TW, Smith JD, Everts E, Cook TA (1980) Dacron mesh tray and cancellous bone in reconstruction of mandibular defects. Arch Otolaryngol Head Neck Surg 8:78–83
12.
go back to reference Wersäll J, Bergstedt H, Körlof B, Lind MG (1984) Split-rib graft for reconstruction of the mandible. Otolaryngol Head Neck Surg 92:270–275 Wersäll J, Bergstedt H, Körlof B, Lind MG (1984) Split-rib graft for reconstruction of the mandible. Otolaryngol Head Neck Surg 92:270–275
13.
go back to reference Taylor GI, Townsend P, Corlett R (1979) Superiority of the deep circumflex iliac vessels as the supply for free groin flaps. Experimental work. Plast Reconstr Surg 64(5):595–604PubMedCrossRef Taylor GI, Townsend P, Corlett R (1979) Superiority of the deep circumflex iliac vessels as the supply for free groin flaps. Experimental work. Plast Reconstr Surg 64(5):595–604PubMedCrossRef
14.
go back to reference Swartz WM, Banis Newton JCED (1986) The osteocutaneous scapular flap for mandibular and maxillary reconstruction. Plast Reconstr Surg 77(4):530–545PubMedCrossRef Swartz WM, Banis Newton JCED (1986) The osteocutaneous scapular flap for mandibular and maxillary reconstruction. Plast Reconstr Surg 77(4):530–545PubMedCrossRef
15.
go back to reference Hidalgo DA (1989) Fibula free flap: a new method of mandible reconstruction. Plast Reconstr Surg 84(1):71–79PubMedCrossRef Hidalgo DA (1989) Fibula free flap: a new method of mandible reconstruction. Plast Reconstr Surg 84(1):71–79PubMedCrossRef
16.
go back to reference Bradley PF (1982) A two-stage procedure for reimplantation of autogenous freeze-treated mandibular bone. J Oral Maxillofac Surg 40:278PubMedCrossRef Bradley PF (1982) A two-stage procedure for reimplantation of autogenous freeze-treated mandibular bone. J Oral Maxillofac Surg 40:278PubMedCrossRef
17.
go back to reference Dong YJ, Zhang GZ, Wang SP, Li Z (1996) The use of immediate frozen autogenous mandible, for benign tumour mandibular reconstruction. Br J Oral Maxillofac Surg 34(1):58–61PubMedCrossRef Dong YJ, Zhang GZ, Wang SP, Li Z (1996) The use of immediate frozen autogenous mandible, for benign tumour mandibular reconstruction. Br J Oral Maxillofac Surg 34(1):58–61PubMedCrossRef
18.
go back to reference Kuo YR, Shih HS, Chen CC et al (2010) Free fibula osteocutaneous flap with soleus muscle as a chimeric flap for reconstructing mandibular segmental defect after oral cancer ablation. Ann Plast Surg 64(6):738–742PubMedCrossRef Kuo YR, Shih HS, Chen CC et al (2010) Free fibula osteocutaneous flap with soleus muscle as a chimeric flap for reconstructing mandibular segmental defect after oral cancer ablation. Ann Plast Surg 64(6):738–742PubMedCrossRef
19.
go back to reference Bak M, Jacobson AS, Buchbinder D, Urken ML (2010) Contemporary reconstruction of the mandible. Oral Oncol 46(2):71–76PubMedCrossRef Bak M, Jacobson AS, Buchbinder D, Urken ML (2010) Contemporary reconstruction of the mandible. Oral Oncol 46(2):71–76PubMedCrossRef
20.
21.
go back to reference Misch CE, Qu ZM, Bidez MW (1999) Mechanical properties of trabecular bone in the human mandible: implications for dental implant treatment planning and surgical placement. J Oral Maxillofac Surg 57:700–706PubMedCrossRef Misch CE, Qu ZM, Bidez MW (1999) Mechanical properties of trabecular bone in the human mandible: implications for dental implant treatment planning and surgical placement. J Oral Maxillofac Surg 57:700–706PubMedCrossRef
22.
go back to reference Yi WJ, Heo MS, Lee SS, Choi SC, Huh KH, Lee SP (2007) Direct measurement of trabecular bone anisotropy using directional fractal dimension and principal axes of inertia. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 104:10–116CrossRef Yi WJ, Heo MS, Lee SS, Choi SC, Huh KH, Lee SP (2007) Direct measurement of trabecular bone anisotropy using directional fractal dimension and principal axes of inertia. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 104:10–116CrossRef
23.
go back to reference Jewer DD, Boyd JB, Manktelow RT, Zuker RM, Rosen IB, Gullane PJ et al (1989) Orofacial and mandibular reconstruction with the iliac crest free flap: a review of 60 cases and a new method of classification. Plast Reconstr Surg 84:391–405 Jewer DD, Boyd JB, Manktelow RT, Zuker RM, Rosen IB, Gullane PJ et al (1989) Orofacial and mandibular reconstruction with the iliac crest free flap: a review of 60 cases and a new method of classification. Plast Reconstr Surg 84:391–405
24.
go back to reference Maurer P, Eckert AW, Kriwalsky MS, Schubert J (2010) Scope and limitations of methods of mandibular reconstruction: a long-term follow-up. Br J Oral Maxillofac Surg 48:100–104 Maurer P, Eckert AW, Kriwalsky MS, Schubert J (2010) Scope and limitations of methods of mandibular reconstruction: a long-term follow-up. Br J Oral Maxillofac Surg 48:100–104
25.
go back to reference Schusterman MA, Harris SW, Raymond AK, Goepfert H (1993) Immediate free flap mandibular reconstruction: significance of adequate surgical margins. Head Neck 15:204PubMedCrossRef Schusterman MA, Harris SW, Raymond AK, Goepfert H (1993) Immediate free flap mandibular reconstruction: significance of adequate surgical margins. Head Neck 15:204PubMedCrossRef
26.
go back to reference Lawson W, Loscalzo LJ, Baek SM et al (1982) Experience with immediate and delayed mandibular reconstruction. Laryngoscope 92:5PubMedCrossRef Lawson W, Loscalzo LJ, Baek SM et al (1982) Experience with immediate and delayed mandibular reconstruction. Laryngoscope 92:5PubMedCrossRef
27.
go back to reference Marx RE, Ames JR (1982) The use of hyperbaric oxygen therapy in bony reconstruction of the irradiated and tissue deficient patient. J Oral Maxillofac Surg 40:410CrossRef Marx RE, Ames JR (1982) The use of hyperbaric oxygen therapy in bony reconstruction of the irradiated and tissue deficient patient. J Oral Maxillofac Surg 40:410CrossRef
29.
go back to reference Carlson ER, Monteleone K (2004) An analysis of inadvertent perforations of mucosa and skin concurrent with mandibular reconstruction. J Oral Maxillofac Surg 62:1103PubMedCrossRef Carlson ER, Monteleone K (2004) An analysis of inadvertent perforations of mucosa and skin concurrent with mandibular reconstruction. J Oral Maxillofac Surg 62:1103PubMedCrossRef
30.
go back to reference Cordeiro PG, Hidalgo DA (1995) Conceptual considerations in mandibular reconstruction. Clin Plast Surg 22:61PubMed Cordeiro PG, Hidalgo DA (1995) Conceptual considerations in mandibular reconstruction. Clin Plast Surg 22:61PubMed
31.
go back to reference Baker A, McMahon J, Parmar S (2001) Immediate reconstruction of continuity defects of the mandible after tumor surgery. J Oral Maxillofac Surg 59:1333PubMedCrossRef Baker A, McMahon J, Parmar S (2001) Immediate reconstruction of continuity defects of the mandible after tumor surgery. J Oral Maxillofac Surg 59:1333PubMedCrossRef
33.
go back to reference Netscher DT, Meade RA, Goodman CM et al (2000) Quality of life and disease specific functional status following microvascular reconstruction for advanced (T3 and T4) oropharyngeal cancers. Plast Reconstr Surg 105:1628PubMedCrossRef Netscher DT, Meade RA, Goodman CM et al (2000) Quality of life and disease specific functional status following microvascular reconstruction for advanced (T3 and T4) oropharyngeal cancers. Plast Reconstr Surg 105:1628PubMedCrossRef
34.
go back to reference Weymuller EA, Yueh B, Deleyiannis FWB et al (2000) Quality of life in patients with head and neck cancer. Arch Otolaryngol Head Neck Surg 126:329PubMedCrossRef Weymuller EA, Yueh B, Deleyiannis FWB et al (2000) Quality of life in patients with head and neck cancer. Arch Otolaryngol Head Neck Surg 126:329PubMedCrossRef
35.
go back to reference Boyd JB, Mullholland RS, Davidson J et al (1995) The free flap and plate in oromandibular reconstruction: long-term review and indications. Plast Reconstr Surg 95:1018PubMedCrossRef Boyd JB, Mullholland RS, Davidson J et al (1995) The free flap and plate in oromandibular reconstruction: long-term review and indications. Plast Reconstr Surg 95:1018PubMedCrossRef
37.
go back to reference Gullane PJ, Holmes H (1976) Mandibular reconstruction new concept. Arch Otolaryngol Head Neck Surg 112:714–719CrossRef Gullane PJ, Holmes H (1976) Mandibular reconstruction new concept. Arch Otolaryngol Head Neck Surg 112:714–719CrossRef
38.
go back to reference Urken ML (1991) Composite free flaps in oro-mandibular reconstruction. Arch Otolaryngol Head Neck Surg 117:724–732PubMedCrossRef Urken ML (1991) Composite free flaps in oro-mandibular reconstruction. Arch Otolaryngol Head Neck Surg 117:724–732PubMedCrossRef
39.
40.
go back to reference Peled M, El-Naaj IA, Lipin Y, Ardekian L (2005) The use of free fibular flap for functional mandibular reconstruction. J Oral Maxillofac Surg 63:220–224PubMedCrossRef Peled M, El-Naaj IA, Lipin Y, Ardekian L (2005) The use of free fibular flap for functional mandibular reconstruction. J Oral Maxillofac Surg 63:220–224PubMedCrossRef
41.
go back to reference Yim KK, Wei FC (1994) Fibula osteoseptocutaneous flap for mandible reconstruction. Microsurgery 15(4):245–249PubMedCrossRef Yim KK, Wei FC (1994) Fibula osteoseptocutaneous flap for mandible reconstruction. Microsurgery 15(4):245–249PubMedCrossRef
42.
go back to reference Haughey BH, Fredrickson JM, Lerrick AJ et al (1994) Fibular and iliac crest osteomuscular free flap reconstruction of the oral cavity. Laryngoscope 104:1305PubMedCrossRef Haughey BH, Fredrickson JM, Lerrick AJ et al (1994) Fibular and iliac crest osteomuscular free flap reconstruction of the oral cavity. Laryngoscope 104:1305PubMedCrossRef
43.
go back to reference Vuillemin T, Raveh J, Sutter F (1998) Mandibular reconstruction with the titanium hollow screw reconstruction plate (THORP) system: evaluation of 62 cases. Plast Reconstr Surg 82:804CrossRef Vuillemin T, Raveh J, Sutter F (1998) Mandibular reconstruction with the titanium hollow screw reconstruction plate (THORP) system: evaluation of 62 cases. Plast Reconstr Surg 82:804CrossRef
44.
go back to reference Schusterman MA, Reece KP, Kroll SS et al (1991) Use of the A–O plate for mandibular reconstruction in cancer patients. Plast Reconstr Surg 88:588–593PubMedCrossRef Schusterman MA, Reece KP, Kroll SS et al (1991) Use of the A–O plate for mandibular reconstruction in cancer patients. Plast Reconstr Surg 88:588–593PubMedCrossRef
45.
go back to reference Chow J, Hill J (1986) Primary mandibular reconstruction using the A–O reconstruction plate. Laryngoscope 96:768–773PubMedCrossRef Chow J, Hill J (1986) Primary mandibular reconstruction using the A–O reconstruction plate. Laryngoscope 96:768–773PubMedCrossRef
46.
47.
go back to reference Guyuron B, Lasa C (1992) Unpredictable growth pattern of costochondral graft. Plast Reconstr Surg 90:880–886PubMedCrossRef Guyuron B, Lasa C (1992) Unpredictable growth pattern of costochondral graft. Plast Reconstr Surg 90:880–886PubMedCrossRef
48.
go back to reference Medra AM (2005) Follow up of mandibular costochondral grafts after release of ankylosis of the temporomandibular joints. Br J Oral Maxillofac Surg 43(2):118–122PubMedCrossRef Medra AM (2005) Follow up of mandibular costochondral grafts after release of ankylosis of the temporomandibular joints. Br J Oral Maxillofac Surg 43(2):118–122PubMedCrossRef
49.
go back to reference Lata J, Kapila BK (2000) Overgrowth of a costochondral graft in temporomandibular joint reconstructive surgery: an uncommon complication. Quintessence Int 31(6):412–414PubMed Lata J, Kapila BK (2000) Overgrowth of a costochondral graft in temporomandibular joint reconstructive surgery: an uncommon complication. Quintessence Int 31(6):412–414PubMed
50.
go back to reference Fernandes R, Fattahi T, Steinberg B (2006) Costochondral rib grafts in mandibular reconstruction. Atlas Oral Maxillofac Surg Clin North Am 14(2):179–183PubMedCrossRef Fernandes R, Fattahi T, Steinberg B (2006) Costochondral rib grafts in mandibular reconstruction. Atlas Oral Maxillofac Surg Clin North Am 14(2):179–183PubMedCrossRef
51.
go back to reference Caccamese JF, Ruiz RL, Costello BJ (2005) Costochondral rib grafting. Atlas Oral Maxillofac Surg Clin North Am 13:139–149PubMedCrossRef Caccamese JF, Ruiz RL, Costello BJ (2005) Costochondral rib grafting. Atlas Oral Maxillofac Surg Clin North Am 13:139–149PubMedCrossRef
52.
go back to reference Hamaker RC (1981) Irradiated autogenous mandibular grafts in primary reconstructions. Laryngoscope 91:1031–1051PubMedCrossRef Hamaker RC (1981) Irradiated autogenous mandibular grafts in primary reconstructions. Laryngoscope 91:1031–1051PubMedCrossRef
53.
go back to reference Leipzig B, Cummings CW (1984) The current status of mandibular reconstruction using autogenous frozen mandibular grafts. Head Neck Surg 8:992–998CrossRef Leipzig B, Cummings CW (1984) The current status of mandibular reconstruction using autogenous frozen mandibular grafts. Head Neck Surg 8:992–998CrossRef
54.
go back to reference Schmoper RR (1983) Mandibular reconstruction using a special plate: animal experiments and clinical appearance. J Maxillofac Surg 11:99–108CrossRef Schmoper RR (1983) Mandibular reconstruction using a special plate: animal experiments and clinical appearance. J Maxillofac Surg 11:99–108CrossRef
55.
go back to reference Burwell RG (1964) Studies in transplantation of bone. VII. The fresh composite homograft-autograft of cancellous bone; an analysis of factors leading to osteogenesis in marrow transplants and in marrow-containing bone grafts. J Bone Joint Surg Br 46:110–140PubMed Burwell RG (1964) Studies in transplantation of bone. VII. The fresh composite homograft-autograft of cancellous bone; an analysis of factors leading to osteogenesis in marrow transplants and in marrow-containing bone grafts. J Bone Joint Surg Br 46:110–140PubMed
56.
go back to reference Rappaport I, Boyne PV, Nethery J (1971) The particulate graft in tumor surgery. Am J Surg 122(6):748–755PubMedCrossRef Rappaport I, Boyne PV, Nethery J (1971) The particulate graft in tumor surgery. Am J Surg 122(6):748–755PubMedCrossRef
57.
go back to reference Boyne PJ (1969) Restoration of osseous defects in maxillofacial casualities. J Am Dent Assoc 78(4):767–776PubMedCrossRef Boyne PJ (1969) Restoration of osseous defects in maxillofacial casualities. J Am Dent Assoc 78(4):767–776PubMedCrossRef
58.
go back to reference Leake DL, Rappoport M (1972) Mandibular reconstruction: bone induction in an alloplastic tray. Surgery 72(2):332–336PubMed Leake DL, Rappoport M (1972) Mandibular reconstruction: bone induction in an alloplastic tray. Surgery 72(2):332–336PubMed
59.
go back to reference Cheung LK, Samman N, Tong AC, Tideman H (1994) Mandibular reconstruction with the Dacron urethane tray: a radiologic assessment of bone remodeling. J Oral Maxillofac Surg 52(4):373–380 (discussion 381)PubMedCrossRef Cheung LK, Samman N, Tong AC, Tideman H (1994) Mandibular reconstruction with the Dacron urethane tray: a radiologic assessment of bone remodeling. J Oral Maxillofac Surg 52(4):373–380 (discussion 381)PubMedCrossRef
60.
go back to reference Cheung LK, Samman N, Chow TW, Clark RKF, Tideman H (1997) A bone graft condensing syringe system for maxillofacial reconstructive surgery. Br J Oral Maxillofac Surg 35:267–270PubMedCrossRef Cheung LK, Samman N, Chow TW, Clark RKF, Tideman H (1997) A bone graft condensing syringe system for maxillofacial reconstructive surgery. Br J Oral Maxillofac Surg 35:267–270PubMedCrossRef
61.
go back to reference Kinoshita Y, Kobayashi M, Hidaka T, Ikada Y (1997) Reconstruction of mandibular continuity defects in dogs using poly (l-lactide) mesh and autogenic particulate cancellous bone and marrow: preliminary report. J Oral Maxillofac Surg 55(7):718–723 (discussion 723–724)PubMedCrossRef Kinoshita Y, Kobayashi M, Hidaka T, Ikada Y (1997) Reconstruction of mandibular continuity defects in dogs using poly (l-lactide) mesh and autogenic particulate cancellous bone and marrow: preliminary report. J Oral Maxillofac Surg 55(7):718–723 (discussion 723–724)PubMedCrossRef
62.
go back to reference Louis P, Holmes J, Fernandes R (2004) Resorbable mesh as a containment system in reconstruction of the atrophic mandible fracture. J Oral Maxillofac Surg 62(6):719–723PubMedCrossRef Louis P, Holmes J, Fernandes R (2004) Resorbable mesh as a containment system in reconstruction of the atrophic mandible fracture. J Oral Maxillofac Surg 62(6):719–723PubMedCrossRef
63.
go back to reference Takagi S, Chow LC, Markovic M, Friedman CD, Costantino PD (2001) Morphological and phase characterizations of retrieved calcium phosphate cement implants. J Biomed Mater Res 58(1):36–41PubMedCrossRef Takagi S, Chow LC, Markovic M, Friedman CD, Costantino PD (2001) Morphological and phase characterizations of retrieved calcium phosphate cement implants. J Biomed Mater Res 58(1):36–41PubMedCrossRef
64.
go back to reference Samman N, Cheung LK, Tideman H (1996) Functional reconstruction of the jaws: new concepts. Ann R Australas Coll Dent Surg 13:184–192PubMed Samman N, Cheung LK, Tideman H (1996) Functional reconstruction of the jaws: new concepts. Ann R Australas Coll Dent Surg 13:184–192PubMed
65.
go back to reference Tideman H, Samman N, Cheung LK (1998) Functional reconstruction of the mandible: a modified titanium mesh system. Int J Oral Maxillofac Surg 27(5):339–345PubMedCrossRef Tideman H, Samman N, Cheung LK (1998) Functional reconstruction of the mandible: a modified titanium mesh system. Int J Oral Maxillofac Surg 27(5):339–345PubMedCrossRef
66.
go back to reference Warnke PH, Springer IN, Wiltfang J, Acil Y, Eufinger H, Wehmöller M, Russo PA, Bolte H, Sherry E, Behrens E, Terheyden H (2004) Growth and transplantation of a custom vascularised bone graft in a man. Lancet 364(9436):766–770PubMedCrossRef Warnke PH, Springer IN, Wiltfang J, Acil Y, Eufinger H, Wehmöller M, Russo PA, Bolte H, Sherry E, Behrens E, Terheyden H (2004) Growth and transplantation of a custom vascularised bone graft in a man. Lancet 364(9436):766–770PubMedCrossRef
67.
go back to reference Celeste AJ, Iannazzi JA, Taylor RC, Hewick RM, Rosen V, Wang EA, Wozney JM (1990) Identification of transforming growth factor beta family members present in bone-inductive protein purified from bovine bone. Proc Natl Acad Sci USA 87(24):9843–9847PubMedPubMedCentralCrossRef Celeste AJ, Iannazzi JA, Taylor RC, Hewick RM, Rosen V, Wang EA, Wozney JM (1990) Identification of transforming growth factor beta family members present in bone-inductive protein purified from bovine bone. Proc Natl Acad Sci USA 87(24):9843–9847PubMedPubMedCentralCrossRef
68.
go back to reference Moghadam HG, Urist MR, Sandor GK, Clokie CM (2001) Successful mandibular reconstruction using a BMP bioimplant. J Craniofac Surg 12(2):119–127 (discussion 128)PubMedCrossRef Moghadam HG, Urist MR, Sandor GK, Clokie CM (2001) Successful mandibular reconstruction using a BMP bioimplant. J Craniofac Surg 12(2):119–127 (discussion 128)PubMedCrossRef
69.
go back to reference Herford AS, Boyne PJ (2008) Reconstruction of mandibular continuity defects with bone morphogenetic protein-2 (rhBMP-2). J Oral Maxillofac Surg 66(4):616–624PubMedCrossRef Herford AS, Boyne PJ (2008) Reconstruction of mandibular continuity defects with bone morphogenetic protein-2 (rhBMP-2). J Oral Maxillofac Surg 66(4):616–624PubMedCrossRef
70.
go back to reference Clokie CM, Sándor GK (2008) Reconstruction of 10 major mandibular defects using bioimplants containing BMP-7. J Can Dent Assoc 74(1):67–72PubMed Clokie CM, Sándor GK (2008) Reconstruction of 10 major mandibular defects using bioimplants containing BMP-7. J Can Dent Assoc 74(1):67–72PubMed
71.
go back to reference Carter TG, Brar PS, Tolas A, Beirne OR (2008) Off-label use of recombinant human bone morphogenetic protein-2 (rhBMP-2) for reconstruction of mandibular bone defects in humans. J Oral Maxillofac Surg 66(7):1417–1425PubMedCrossRef Carter TG, Brar PS, Tolas A, Beirne OR (2008) Off-label use of recombinant human bone morphogenetic protein-2 (rhBMP-2) for reconstruction of mandibular bone defects in humans. J Oral Maxillofac Surg 66(7):1417–1425PubMedCrossRef
72.
go back to reference Glied AN, Kraut RA (2010) Off-label use of rhBMP-2 for reconstruction of critical-sized mandibular defects. N Y State Dent J 76(4):32–35PubMed Glied AN, Kraut RA (2010) Off-label use of rhBMP-2 for reconstruction of critical-sized mandibular defects. N Y State Dent J 76(4):32–35PubMed
73.
go back to reference Herford AS, Cicciù M (2010) Recombinant human bone morphogenetic protein type 2 jaw reconstruction in patients affected by giant cell tumor. J Craniofac Surg 21(6):1970–1975PubMedCrossRef Herford AS, Cicciù M (2010) Recombinant human bone morphogenetic protein type 2 jaw reconstruction in patients affected by giant cell tumor. J Craniofac Surg 21(6):1970–1975PubMedCrossRef
74.
go back to reference Hidalgo DA (1991) Aesthetic improvements in free-flap mandible reconstruction. Plast Reconstr Surg 88(4):574–585 (discussion 586–587)PubMedCrossRef Hidalgo DA (1991) Aesthetic improvements in free-flap mandible reconstruction. Plast Reconstr Surg 88(4):574–585 (discussion 586–587)PubMedCrossRef
75.
go back to reference Hidalgo DA, Rekow A (1995) Review of 60 consecutive fibula free flap mandible reconstructions. Plast Reconstr Surg 96:585PubMedCrossRef Hidalgo DA, Rekow A (1995) Review of 60 consecutive fibula free flap mandible reconstructions. Plast Reconstr Surg 96:585PubMedCrossRef
76.
go back to reference Frodel JL Jr, Funk GF, Cappis DT et al (1993) Osseointegrated implants: a comparative study of bone thickness in four vascularized bone flaps. Plast Reconstr Surg 92:449–455PubMedCrossRef Frodel JL Jr, Funk GF, Cappis DT et al (1993) Osseointegrated implants: a comparative study of bone thickness in four vascularized bone flaps. Plast Reconstr Surg 92:449–455PubMedCrossRef
77.
go back to reference Kuriloff DB, Sullivan MJ (1991) Mandibular re-construction using vascularized bone graft. Otolaryngol Clin North Am 24:1391–1418PubMed Kuriloff DB, Sullivan MJ (1991) Mandibular re-construction using vascularized bone graft. Otolaryngol Clin North Am 24:1391–1418PubMed
78.
go back to reference O’Leary MJ, Martin PJ, Hayden RE (1994) The neurocutaneous free fibula flap in mandibular reconstruction. Otolaryngol Clin North Am 27(6):1081–1096PubMed O’Leary MJ, Martin PJ, Hayden RE (1994) The neurocutaneous free fibula flap in mandibular reconstruction. Otolaryngol Clin North Am 27(6):1081–1096PubMed
80.
go back to reference Gilbert A (1981) Free vascularized bone grafts. Int Surg 66(1):27–31PubMed Gilbert A (1981) Free vascularized bone grafts. Int Surg 66(1):27–31PubMed
81.
go back to reference Wol KD, Ervens J, Herzog K, Hoefmister B (1996) Experience with the osteocutaneous fibula flap: an analysis of 24 consecutive reconstructions of composite mandibular defects. J Cranio-Maxillofac Surg 24:330–338CrossRef Wol KD, Ervens J, Herzog K, Hoefmister B (1996) Experience with the osteocutaneous fibula flap: an analysis of 24 consecutive reconstructions of composite mandibular defects. J Cranio-Maxillofac Surg 24:330–338CrossRef
82.
go back to reference Goodacre TE, Walker CJ, Jawad AS, Jackson AM, Brough MD (1990) Donor site morbidity following osteocutaneous free fibula transfer. Br J Plast Surg 43(4):410–412PubMedCrossRef Goodacre TE, Walker CJ, Jawad AS, Jackson AM, Brough MD (1990) Donor site morbidity following osteocutaneous free fibula transfer. Br J Plast Surg 43(4):410–412PubMedCrossRef
83.
go back to reference Thoma A, Levis C, Young JE (2005) Oromandibular reconstruction after cancer resection. Clin Plastic Surg 32(3): 361–375 Thoma A, Levis C, Young JE (2005) Oromandibular reconstruction after cancer resection. Clin Plastic Surg 32(3): 361–375
84.
go back to reference Soutar DS, Widdowson WP (1986) Immediate reconstruction of the mandible using a re-vascularized segment of radius. Head Neck Surg 8(4):232–246 Soutar DS, Widdowson WP (1986) Immediate reconstruction of the mandible using a re-vascularized segment of radius. Head Neck Surg 8(4):232–246
85.
go back to reference Jaquet Y et al (2012) Radial forearm free flap donor site morbidity ulnar-based transposition flap vs. split-thickness skin graft. Arch Otolaryngol Head Neck Surg 138(1):38–43PubMedCrossRef Jaquet Y et al (2012) Radial forearm free flap donor site morbidity ulnar-based transposition flap vs. split-thickness skin graft. Arch Otolaryngol Head Neck Surg 138(1):38–43PubMedCrossRef
86.
go back to reference Rockwell GM, Thoma A (2004) Should the donor radius be plated prophylactically after harvest of a radial osteocutaneous flap? A cost-effectiveness analysis. J Reconstr Microsurg 20:297–306PubMedCrossRef Rockwell GM, Thoma A (2004) Should the donor radius be plated prophylactically after harvest of a radial osteocutaneous flap? A cost-effectiveness analysis. J Reconstr Microsurg 20:297–306PubMedCrossRef
87.
go back to reference Cummings (1995) Discuss the options for mandibular reconstruction in lateral and anterior arch defects (non-vascularized vs. vascularized bone grafts). Sem Surg Oncol 11:190CrossRef Cummings (1995) Discuss the options for mandibular reconstruction in lateral and anterior arch defects (non-vascularized vs. vascularized bone grafts). Sem Surg Oncol 11:190CrossRef
88.
go back to reference Baker SR, Sullivan MJ (1988) Osteocutaneous free scapular flap for one stage mandibular reconstruction. Arch Otolaryngol Head Neck Surg 114:267–277PubMedCrossRef Baker SR, Sullivan MJ (1988) Osteocutaneous free scapular flap for one stage mandibular reconstruction. Arch Otolaryngol Head Neck Surg 114:267–277PubMedCrossRef
89.
go back to reference Urken ML, Buchbinder D, Weinberg H et al (1989) Primary placement of osseointegrated implants in microvascular mandibular reconstruction. Otolaryngol Head Neck Surg 101:58–73 Urken ML, Buchbinder D, Weinberg H et al (1989) Primary placement of osseointegrated implants in microvascular mandibular reconstruction. Otolaryngol Head Neck Surg 101:58–73
90.
go back to reference Sullivan MJ et al (1990) The free scapular flap for head and neck reconstruction. Am J Otolaryngol 11:319–327CrossRef Sullivan MJ et al (1990) The free scapular flap for head and neck reconstruction. Am J Otolaryngol 11:319–327CrossRef
91.
go back to reference Lueg E (2004) The anterolateral thigh flap: radial forearm’s “big brother” for extensive soft tissue head and neck defects. Arch Otolaryngol Head Neck Surg 130:813–818PubMedCrossRef Lueg E (2004) The anterolateral thigh flap: radial forearm’s “big brother” for extensive soft tissue head and neck defects. Arch Otolaryngol Head Neck Surg 130:813–818PubMedCrossRef
92.
go back to reference Wei FC, Jain V, Celik N et al (2002) Have we found an ideal soft-tissue flap? An experience with 672 anterolateral thigh flaps. Plast Reconstr Surg 109:2219–2226PubMedCrossRef Wei FC, Jain V, Celik N et al (2002) Have we found an ideal soft-tissue flap? An experience with 672 anterolateral thigh flaps. Plast Reconstr Surg 109:2219–2226PubMedCrossRef
93.
go back to reference Yu P (2004) Characteristics of the anterolateral thigh flap in a Western population and its application in head and neck reconstruction. Head Neck 26:759–769PubMedCrossRef Yu P (2004) Characteristics of the anterolateral thigh flap in a Western population and its application in head and neck reconstruction. Head Neck 26:759–769PubMedCrossRef
94.
go back to reference Walton RL (1993) Discussion. Free anterolateral thigh flaps for reconstruction of head and neck defects. Plast Reconstr Surg 92:429–430CrossRef Walton RL (1993) Discussion. Free anterolateral thigh flaps for reconstruction of head and neck defects. Plast Reconstr Surg 92:429–430CrossRef
95.
go back to reference Wei FC, Jain V, Suominen S et al (1988) Confusion among perforator flaps: What is a true perforator flap? Plast Reconstr Surg 81:561CrossRef Wei FC, Jain V, Suominen S et al (1988) Confusion among perforator flaps: What is a true perforator flap? Plast Reconstr Surg 81:561CrossRef
96.
go back to reference Koshima I (2000) Discussion. Free anterolateral thigh flap for reconstruction of head and neck defects following cancer ablation. Plast Reconstr Surg 105:2358–2360PubMedCrossRef Koshima I (2000) Discussion. Free anterolateral thigh flap for reconstruction of head and neck defects following cancer ablation. Plast Reconstr Surg 105:2358–2360PubMedCrossRef
98.
go back to reference McLeod AM, Robinson DW (1982) Reconstruction of defects involving the mandible and floor of mouth by free osteocutaneous flaps derived from the foot. Br J Plast Surg 35:239–248CrossRef McLeod AM, Robinson DW (1982) Reconstruction of defects involving the mandible and floor of mouth by free osteocutaneous flaps derived from the foot. Br J Plast Surg 35:239–248CrossRef
99.
go back to reference Urken ML, Buchbinder D, Costantino PD et al (1998) Oromandibular reconstruction using microvascular composite flaps: report of 210 cases. Arch Otolaryngol Head Neck Surg 124(1):46–55PubMedCrossRef Urken ML, Buchbinder D, Costantino PD et al (1998) Oromandibular reconstruction using microvascular composite flaps: report of 210 cases. Arch Otolaryngol Head Neck Surg 124(1):46–55PubMedCrossRef
100.
go back to reference Manchester WM (1972) Some technical improvements in the reconstruction of the mandible and temporomandibular joint. Plast Reconstr Surg 50(3):249–256PubMedCrossRef Manchester WM (1972) Some technical improvements in the reconstruction of the mandible and temporomandibular joint. Plast Reconstr Surg 50(3):249–256PubMedCrossRef
101.
go back to reference Urken ML, Vickery C, Weinberg H, Buchbinder D, Lawson W, Biller HF (1989) The internal oblique-iliac crest osteomyocutaneous free flap in oromandibular reconstruction. Report of 20 cases. Arch Otolaryngol Head Neck Surg 115(3):339–349PubMedCrossRef Urken ML, Vickery C, Weinberg H, Buchbinder D, Lawson W, Biller HF (1989) The internal oblique-iliac crest osteomyocutaneous free flap in oromandibular reconstruction. Report of 20 cases. Arch Otolaryngol Head Neck Surg 115(3):339–349PubMedCrossRef
102.
go back to reference Rogers SN, Lakshmiah SR, Narayan B et al (2003) A comparison of the long-term morbidity following deep circumflex iliac and fibula free flaps for reconstruction following head and neck cancer. Plast Reconstr Surg 112(6):1517–1525PubMedCrossRef Rogers SN, Lakshmiah SR, Narayan B et al (2003) A comparison of the long-term morbidity following deep circumflex iliac and fibula free flaps for reconstruction following head and neck cancer. Plast Reconstr Surg 112(6):1517–1525PubMedCrossRef
103.
go back to reference Ramasastry SS, Tucker JB, Swartz WM et al (1984) The internal oblique muscle flap: an anatomic and clinical study. Plast Reconstr Surg 73:721–730PubMedCrossRef Ramasastry SS, Tucker JB, Swartz WM et al (1984) The internal oblique muscle flap: an anatomic and clinical study. Plast Reconstr Surg 73:721–730PubMedCrossRef
104.
go back to reference Seikaly H, Calhoun K, Rassekh C, Slaughter D (1997) The clavipectoral osteomyocutaneous free flap. Otolaryngol Head Neck Surg 117(5):547–554PubMedCrossRef Seikaly H, Calhoun K, Rassekh C, Slaughter D (1997) The clavipectoral osteomyocutaneous free flap. Otolaryngol Head Neck Surg 117(5):547–554PubMedCrossRef
105.
go back to reference Milroy BC, Korula P (1988) Vascularized innervated transfer of the clavicular head of the pectoralis major muscle in established facial paralysis. Ann Plast Surg 20:273–282CrossRef Milroy BC, Korula P (1988) Vascularized innervated transfer of the clavicular head of the pectoralis major muscle in established facial paralysis. Ann Plast Surg 20:273–282CrossRef
106.
go back to reference Reid CD, Taylor GI, Waterhouse N (1986) The clavicular head of pectoralis major musculocutaneous free flap. Br J Plast Surg 39:57–65PubMedCrossRef Reid CD, Taylor GI, Waterhouse N (1986) The clavicular head of pectoralis major musculocutaneous free flap. Br J Plast Surg 39:57–65PubMedCrossRef
107.
go back to reference Seikaly H, Chau J, Li F, Driscoll B, Seikaly D, Calhoun J, Calhoun KH (2003) Bone that best matches the properties of the mandible. J Otolaryngol 32(4):262–265PubMedCrossRef Seikaly H, Chau J, Li F, Driscoll B, Seikaly D, Calhoun J, Calhoun KH (2003) Bone that best matches the properties of the mandible. J Otolaryngol 32(4):262–265PubMedCrossRef
108.
go back to reference Pogrel MA, Podlesh S, Anthony JP et al (1997) A comparison of vascularized and nonvascularized bone grafts for reconstruction of mandibular continuity defects. J Oral Maxillofac Surg 55:1200–1206PubMedCrossRef Pogrel MA, Podlesh S, Anthony JP et al (1997) A comparison of vascularized and nonvascularized bone grafts for reconstruction of mandibular continuity defects. J Oral Maxillofac Surg 55:1200–1206PubMedCrossRef
109.
go back to reference Granström G, Jacobsson M, Tjellström A (1992) Titanium implants in irradiated tissue: benefits from hyperbaric oxygen. Int J Oral Maxillofac Implants 7:15–25PubMed Granström G, Jacobsson M, Tjellström A (1992) Titanium implants in irradiated tissue: benefits from hyperbaric oxygen. Int J Oral Maxillofac Implants 7:15–25PubMed
110.
go back to reference Marx RE (1983) A new concept in the treatment of osteoradionecrosis. J Oral Maxillofac Surg 41:351–357PubMedCrossRef Marx RE (1983) A new concept in the treatment of osteoradionecrosis. J Oral Maxillofac Surg 41:351–357PubMedCrossRef
111.
go back to reference AleAlam DS, Nuara M, Christian J (2009) Analysis of outcomes of vascularized flap reconstruction in patients with advanced mandibular osteoradionecrosis. Otolaryngol Head Neck Surg 141:196–201CrossRef AleAlam DS, Nuara M, Christian J (2009) Analysis of outcomes of vascularized flap reconstruction in patients with advanced mandibular osteoradionecrosis. Otolaryngol Head Neck Surg 141:196–201CrossRef
112.
go back to reference Dufresne C, Cutting C, Valauri F et al (1987) Reconstruction of mandibular and floor of mouth defects using the trapezius osteomyocutaneous flap. Plast Reconstr Surg 79:687–696PubMedCrossRef Dufresne C, Cutting C, Valauri F et al (1987) Reconstruction of mandibular and floor of mouth defects using the trapezius osteomyocutaneous flap. Plast Reconstr Surg 79:687–696PubMedCrossRef
113.
go back to reference Hirsch DL, Bell RB, Dierks EJ et al (2008) Analysis of microvascular free flaps for reconstruction of advanced mandibular osteoradionecrosis: a retrospective cohort study. J Oral Maxillofac Surg 66:2545–2556PubMedCrossRef Hirsch DL, Bell RB, Dierks EJ et al (2008) Analysis of microvascular free flaps for reconstruction of advanced mandibular osteoradionecrosis: a retrospective cohort study. J Oral Maxillofac Surg 66:2545–2556PubMedCrossRef
114.
go back to reference Foley BD et al (2013) Mandibular reconstruction using computer-aided design and computer-aided manufacturing: an analysis of surgical results. J Oral Maxillofac Surg 71(2):e111–e119PubMedCrossRef Foley BD et al (2013) Mandibular reconstruction using computer-aided design and computer-aided manufacturing: an analysis of surgical results. J Oral Maxillofac Surg 71(2):e111–e119PubMedCrossRef
115.
go back to reference Costantino PD, Shybut G, Friedman CD, Pelzer HL, Masini M, Shindo ML, Sisson GA Sr (1990) Segmental mandibular regeneration by distraction osteogenesis: an experimental study. Arch Otolaryngol Head Neck Surg 116:535–545PubMedCrossRef Costantino PD, Shybut G, Friedman CD, Pelzer HL, Masini M, Shindo ML, Sisson GA Sr (1990) Segmental mandibular regeneration by distraction osteogenesis: an experimental study. Arch Otolaryngol Head Neck Surg 116:535–545PubMedCrossRef
116.
go back to reference Costantino PD, Johnson CS, Friedman CD, Sisson GA (1995) Bone regeneration within a human segmental mandible defect: a preliminary report. Am J Otolaryngol 16:56–65PubMedCrossRef Costantino PD, Johnson CS, Friedman CD, Sisson GA (1995) Bone regeneration within a human segmental mandible defect: a preliminary report. Am J Otolaryngol 16:56–65PubMedCrossRef
117.
go back to reference Herford AS (2004) Use of a plate-guided distraction device for transport distraction osteogenesis of the mandible. J Oral Maxillofac Surg 62:412–420PubMedCrossRef Herford AS (2004) Use of a plate-guided distraction device for transport distraction osteogenesis of the mandible. J Oral Maxillofac Surg 62:412–420PubMedCrossRef
118.
go back to reference González-García R, Naval-Gías L (2010) Transport osteogenesis in the maxillofacial skeleton: the outcomes of a versatile reconstruction method following tumor ablation. Arch Otolaryngol Head Neck Surg 136:243–250PubMedCrossRef González-García R, Naval-Gías L (2010) Transport osteogenesis in the maxillofacial skeleton: the outcomes of a versatile reconstruction method following tumor ablation. Arch Otolaryngol Head Neck Surg 136:243–250PubMedCrossRef
119.
go back to reference Malawer MM, Chou LB (1995) Prosthetic survival and clinical results with use of large segment replacements in the treatment of high-grade bone sarcomas. J Bone Joint Surg Am 77:1154–1165PubMed Malawer MM, Chou LB (1995) Prosthetic survival and clinical results with use of large segment replacements in the treatment of high-grade bone sarcomas. J Bone Joint Surg Am 77:1154–1165PubMed
120.
go back to reference Riede U, Luem M, Ilchmann T, Eucker M, Ochsner PE (2007) The M.E Müller straight stem prosthesis: 15 year follow-up. Survivorship and clinical results. Arch Orthop Trauma Surg 127:587–592PubMedCrossRef Riede U, Luem M, Ilchmann T, Eucker M, Ochsner PE (2007) The M.E Müller straight stem prosthesis: 15 year follow-up. Survivorship and clinical results. Arch Orthop Trauma Surg 127:587–592PubMedCrossRef
121.
go back to reference Tideman H, Lee S (2006) The TL endoprosthesis for mandibular reconstruction—a metallic yet biological approach. Asian J Oral Maxillofac Surg 18:5CrossRef Tideman H, Lee S (2006) The TL endoprosthesis for mandibular reconstruction—a metallic yet biological approach. Asian J Oral Maxillofac Surg 18:5CrossRef
122.
go back to reference Lee S, Goh BT, Tideman H, Stoelinga PJ, Jansen JA (2009) Modular endoprosthesis for mandibular body reconstruction: a clinical, micro-CT and histologic evaluation in eight Macaca fascicularis. Int J Oral Maxillofac Surg 38:40–47PubMedCrossRef Lee S, Goh BT, Tideman H, Stoelinga PJ, Jansen JA (2009) Modular endoprosthesis for mandibular body reconstruction: a clinical, micro-CT and histologic evaluation in eight Macaca fascicularis. Int J Oral Maxillofac Surg 38:40–47PubMedCrossRef
123.
go back to reference Goh BT, Lee S, Tideman H, Stoelinga PJ (2009) Replacement of the condyle and ascending ramus by a modular endoprosthesis in Macaca fascicularis part 1: a clinical and radiographic study. J Oral Maxillofac Surg 67:1392–1400PubMedCrossRef Goh BT, Lee S, Tideman H, Stoelinga PJ (2009) Replacement of the condyle and ascending ramus by a modular endoprosthesis in Macaca fascicularis part 1: a clinical and radiographic study. J Oral Maxillofac Surg 67:1392–1400PubMedCrossRef
124.
go back to reference Wong RC, Tideman H, Merkx MA, Jansen J, Goh SM (2012) The modular endoprosthesis for mandibular body replacement. Part 2: finite element analysis of endoprosthesis reconstruction of the mandible. J Craniomaxillofac Surg 40:e487–e497PubMedCrossRef Wong RC, Tideman H, Merkx MA, Jansen J, Goh SM (2012) The modular endoprosthesis for mandibular body replacement. Part 2: finite element analysis of endoprosthesis reconstruction of the mandible. J Craniomaxillofac Surg 40:e487–e497PubMedCrossRef
125.
go back to reference Gronthos S (2004) Reconstruction of human mandible by tissue engineering. Lancet 9436:735–736CrossRef Gronthos S (2004) Reconstruction of human mandible by tissue engineering. Lancet 9436:735–736CrossRef
126.
go back to reference Warnke PH, Wiltfang J, Springer I, Acil Y, Bolte H, Kosmahl M et al (2006) Man as living bioreactor: fate of an exogenously prepared customized tissue-engineered mandible. Biomaterials 17:3163–3167CrossRef Warnke PH, Wiltfang J, Springer I, Acil Y, Bolte H, Kosmahl M et al (2006) Man as living bioreactor: fate of an exogenously prepared customized tissue-engineered mandible. Biomaterials 17:3163–3167CrossRef
127.
go back to reference Warnke PH, Springer IN, Acil Y, Julga G, Wiltfang J, Ludwig K et al (2006) The mechanical integrity of in vivo engineered heterotopic bone. Biomaterials 7:1081–1087CrossRef Warnke PH, Springer IN, Acil Y, Julga G, Wiltfang J, Ludwig K et al (2006) The mechanical integrity of in vivo engineered heterotopic bone. Biomaterials 7:1081–1087CrossRef
128.
go back to reference Heliotis M, Lavery KM, Ripamonti U, Tsiridis E, di Silvio L (2006) Transformation of a prefabricated hydroxyapatite/osteogenic protein-1implant into a vascularised pedicled bone flap in the human chest. Int J Oral Maxillofac Surg 3:265–269CrossRef Heliotis M, Lavery KM, Ripamonti U, Tsiridis E, di Silvio L (2006) Transformation of a prefabricated hydroxyapatite/osteogenic protein-1implant into a vascularised pedicled bone flap in the human chest. Int J Oral Maxillofac Surg 3:265–269CrossRef
129.
go back to reference Boyne PJ (1971) Transplantation, implantation and grafts. Dent Clin North Am 15:433–453PubMed Boyne PJ (1971) Transplantation, implantation and grafts. Dent Clin North Am 15:433–453PubMed
130.
go back to reference Blake F, Bubenheim M, Heiland M et al (2008) Retrospective assessment of the peri-implant mucosa of implants inserted in reanastomosed or free bone grafts from the fibula or iliac crest. Int J Oral Maxillofac Implants 23:1102–1108PubMed Blake F, Bubenheim M, Heiland M et al (2008) Retrospective assessment of the peri-implant mucosa of implants inserted in reanastomosed or free bone grafts from the fibula or iliac crest. Int J Oral Maxillofac Implants 23:1102–1108PubMed
131.
go back to reference Rohner D, Jaquiery C, Kunz C, Bucher P, Maas H, Hammer B (2003) Maxillofacial reconstruction with prefabricated osseous free flaps: a 3-year experience with 24 patients. Plast Reconstr Surg 112:748–757PubMedCrossRef Rohner D, Jaquiery C, Kunz C, Bucher P, Maas H, Hammer B (2003) Maxillofacial reconstruction with prefabricated osseous free flaps: a 3-year experience with 24 patients. Plast Reconstr Surg 112:748–757PubMedCrossRef
132.
go back to reference Marunick MT, Roumanas ED (1999) Functional criteria for mandibular implant placement post resection and reconstruction for cancer. J Prosthet Dent 82(1):107–113PubMedCrossRef Marunick MT, Roumanas ED (1999) Functional criteria for mandibular implant placement post resection and reconstruction for cancer. J Prosthet Dent 82(1):107–113PubMedCrossRef
134.
go back to reference Garrett N, Roumanas ED, Blackwell KE, Freymiller E, Abemayor E, Wong WK, Gerratt B, Berke G, Beumer J 3rd, Kapur KK (2006) Efficacy of conventional and implant-supported mandibular resection prostheses: study overview and treatment outcomes. J Prosthet Dent 96(1):13–24PubMedCrossRef Garrett N, Roumanas ED, Blackwell KE, Freymiller E, Abemayor E, Wong WK, Gerratt B, Berke G, Beumer J 3rd, Kapur KK (2006) Efficacy of conventional and implant-supported mandibular resection prostheses: study overview and treatment outcomes. J Prosthet Dent 96(1):13–24PubMedCrossRef
137.
go back to reference Foster RD, Anthony JP, Sharma A, Pogrel MA (1999) Vascularized bone flaps versus nonvascularized bone grafts for mandibular reconstruction: an outcome analysis of primary bony union and endosseous implant success. Head Neck 21(1):66–71PubMedCrossRef Foster RD, Anthony JP, Sharma A, Pogrel MA (1999) Vascularized bone flaps versus nonvascularized bone grafts for mandibular reconstruction: an outcome analysis of primary bony union and endosseous implant success. Head Neck 21(1):66–71PubMedCrossRef
138.
go back to reference Weischer T, Mohr C (1999) Ten-year experience in oral implant rehabilitation of cancer patients: treatment concept and proposed criteria for success. Int J Oral Maxillofac Implants 14(4):521–528PubMed Weischer T, Mohr C (1999) Ten-year experience in oral implant rehabilitation of cancer patients: treatment concept and proposed criteria for success. Int J Oral Maxillofac Implants 14(4):521–528PubMed
139.
go back to reference Werkmeister R, Szulczewski D, Walteros-Benz P, Joos U (1999) Rehabilitation with dental implants of oral cancer patients. J Craniomaxillofac Surg 27(1):38–41PubMedCrossRef Werkmeister R, Szulczewski D, Walteros-Benz P, Joos U (1999) Rehabilitation with dental implants of oral cancer patients. J Craniomaxillofac Surg 27(1):38–41PubMedCrossRef
140.
go back to reference Shaw RJ, Sutton AF, Cawood JI, Howell RA, Lowe D, Brown JS, Rogers SN, Vaughan ED (2005) Oral rehabilitation after treatment for head and neck malignancy. Head Neck 27(6):459–470PubMedCrossRef Shaw RJ, Sutton AF, Cawood JI, Howell RA, Lowe D, Brown JS, Rogers SN, Vaughan ED (2005) Oral rehabilitation after treatment for head and neck malignancy. Head Neck 27(6):459–470PubMedCrossRef
141.
go back to reference Sclaroff A, Haughey B, Gay WD, Paniello R (1994) Immediate mandibular reconstruction and placement of dental implants at the time of ablative surgery. Oral Surg Oral Med Oral Pathol 78(6):711–717PubMedCrossRef Sclaroff A, Haughey B, Gay WD, Paniello R (1994) Immediate mandibular reconstruction and placement of dental implants at the time of ablative surgery. Oral Surg Oral Med Oral Pathol 78(6):711–717PubMedCrossRef
Metadata
Title
Mandibular Reconstruction: Overview
Authors
Batchu Pavan Kumar
V. Venkatesh
K. A. Jeevan Kumar
B. Yashwanth Yadav
S. Ram Mohan
Publication date
01-12-2016
Publisher
Springer India
Published in
Journal of Maxillofacial and Oral Surgery / Issue 4/2016
Print ISSN: 0972-8279
Electronic ISSN: 0974-942X
DOI
https://doi.org/10.1007/s12663-015-0766-5

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