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Published in: Current Cardiovascular Imaging Reports 6/2024

Open Access 02-05-2024 | Review

Advanced Cardiovascular Magnetic Resonance Imaging in Takotsubo Syndrome: Update on Feature Tracking and Tissue Mapping

Authors: Matteo Sclafani, Giacomo Tini, Beatrice Musumeci, Alessandro Cianca, Viviana Maestrini, Luca Cacciotti, Luca Arcari

Published in: Current Cardiovascular Imaging Reports | Issue 6/2024

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Abstract

Backgrounds

Takotsubo syndrome (TTS) is an intriguing clinical entity characterized by transient myocardial dysfunction. The precise pathophysiological mechanism of TTS is still unknown, but recent evidence suggests a central role of systemic inflammation associated with adrenergic discharge. Although initially considered benign, TTS has shown several potential short-term and long-term complications and adverse outcomes. To improve understanding and management, advanced cardiovascular magnetic resonance (CMR) techniques, such as feature tracking (FT) and parametric mapping, have gained attention.

Purpose of Review

The purpose of this review is to summarize the current literature on the clinical applications of CMR-FT and mapping in TTS. Additionally, the most significant and recent findings will be discussed.

Recent Findings

FT-CMR enables the parametric quantification of myocardial deformation, allowing a comprehensive evaluation of left ventricular, right ventricular, and atrial function. It provides an accurate definition of areas of myocardial dysfunction and potentially serves as a superior prognostic tool compared to ejection fraction. Tissue mapping techniques enable precise and comprehensive tissue characterization by quantifying areas of oedema, and myocardial fibrosis.

Summary

FT-CMR and mapping techniques serve as valuable prognostic tools both in the acute and chronic phases of TTS. They can detect subtle alterations and pan-cardiac involvement, while also providing important insights into the complex underlying mechanisms of the syndrome.
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Metadata
Title
Advanced Cardiovascular Magnetic Resonance Imaging in Takotsubo Syndrome: Update on Feature Tracking and Tissue Mapping
Authors
Matteo Sclafani
Giacomo Tini
Beatrice Musumeci
Alessandro Cianca
Viviana Maestrini
Luca Cacciotti
Luca Arcari
Publication date
02-05-2024
Publisher
Springer US
Published in
Current Cardiovascular Imaging Reports / Issue 6/2024
Print ISSN: 1941-9066
Electronic ISSN: 1941-9074
DOI
https://doi.org/10.1007/s12410-024-09593-9