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Journal of Nuclear Cardiology
Published in: Journal of Nuclear Cardiology 3/2018

01-06-2018 | Review Article

Invasive assessment of coronary artery disease

Authors: Stylianos A. Pyxaras, MD, William Wijns, MD, PhD, Johan H. C. Reiber, PhD, Jeroen J. Bax, MD, PhD

Published in: Journal of Nuclear Cardiology | Issue 3/2018

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Abstract

Coronary artery disease is associated to high mortality and morbidity rates and an accurate diagnostic assessment during heart catheterization has a fundamental role in prognostic stratification and treatment choices. Coronary angiography has been integrated by intravascular imaging modalities, namely intravascular ultrasound and optical coherence tomography, which allow the precise quantification of the atherosclerotic burden of coronary arteries. The hemodynamic relevance of a given coronary stenosis can be assessed using stress or resting indexes: fractional flow reserve and instantaneous wave-free ratio are both coronary flow surrogates, used to guide percutaneous coronary interventions. This review summarizes the current state-of-the-art of invasive diagnostic methods during heart catheterization and highlights the potential role that an integration of anatomical and functional information enables.
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Metadata
Title
Invasive assessment of coronary artery disease
Authors
Stylianos A. Pyxaras, MD
William Wijns, MD, PhD
Johan H. C. Reiber, PhD
Jeroen J. Bax, MD, PhD
Publication date
01-06-2018
Publisher
Springer US
Published in
Journal of Nuclear Cardiology / Issue 3/2018
Print ISSN: 1071-3581
Electronic ISSN: 1532-6551
DOI
https://doi.org/10.1007/s12350-017-1050-5

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