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Published in: Journal of Nuclear Cardiology 3/2018

01-06-2018 | Original Article

Validation of cadmium–zinc–telluride camera for measurement of left ventricular systolic performance

Authors: Elisabeth Coupez, MD, Charles Merlin, MD, Viateur Tuyisenge, PhD, Laurent Sarry, PhD, Bruno Pereira, PhD, Jean René Lusson, MD, PhD, Louis Boyer, MD, PhD, Lucie Cassagnes, MD, PhD

Published in: Journal of Nuclear Cardiology | Issue 3/2018

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Abstract

Background

There are paucity of data comparing measurements of left ventricular systolic performance using cadmium–zinc–telluride (CZT) semiconductor cameras with other imaging modalities. This study compared the new system with echocardiography (echo) and cardiac magnetic resonance (CMR) imaging.

Methods

60 Patients presenting with ST-elevated myocardial infarction (MI) were included. Each patient underwent echo, myocardial perfusion imaging using Spectrum Dynamics D-SPECT(r) (CZT-SPECT), and CMR 6 weeks after MI. The primary endpoint was the agreement between CZT-SPECT and CMR for left ventricular ejection fraction (LVEF) measurement.

Results

48 of the 60 patients underwent all 3 studies (echo, CMR, and CZT-SPECT) 40 days after admission. CZT-SPECT and CMR LVEF were well correlated (r = .79, P < .0001), as well as CZT-SPECT vs echo and CMR vs echo (r = .79 and .84, respectively, P < .0001). The segmental LV wall thickening and wall motion also showed good concordance between three techniques.

Conclusions

CZT-SPECT is reliable for LVEF measurement.
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Metadata
Title
Validation of cadmium–zinc–telluride camera for measurement of left ventricular systolic performance
Authors
Elisabeth Coupez, MD
Charles Merlin, MD
Viateur Tuyisenge, PhD
Laurent Sarry, PhD
Bruno Pereira, PhD
Jean René Lusson, MD, PhD
Louis Boyer, MD, PhD
Lucie Cassagnes, MD, PhD
Publication date
01-06-2018
Publisher
Springer US
Published in
Journal of Nuclear Cardiology / Issue 3/2018
Print ISSN: 1071-3581
Electronic ISSN: 1532-6551
DOI
https://doi.org/10.1007/s12350-017-0816-0

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