Published in:
01-06-2017 | Editorial
Editorial in response to: PET/CT evaluation of 18F-FDG uptake in pericoronary adipose tissue in patients with stable coronary artery disease: Independent predictor of atherosclerotic lesion formation?
Is there prognostic value in evaluation of 18F-FDG uptake in the pericoronary adipose tissue?
Authors:
Stephanie L. Thorn, PhD, Albert J. Sinusas, MD
Published in:
Journal of Nuclear Cardiology
|
Issue 3/2017
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Excerpt
Atherosclerosis is a chronic progressive disease that can lead to ischemic heart disease or cerebrovascular stroke, two of the worlds’ leading causes of death.
1 Atherosclerosis involves a complex process, and is driven by a cyclic inflammatory response initiated by deposition of low density lipoprotein within arterial walls. Therefore, inflammation is one of the key modulators of plaque development and can lead to plaque rupture or erosion.
2 Recent investigative efforts have focused on technologies and subsequent methodologies that not only detect atherosclerotic plaque and assess the severity of a stenosis, but also attempt to identify the features associated with plaque instability. …