Published in:
01-10-2016 | Editorial
Prognostic impact of TID in regadenoson MPI: Some patients and certain events
Authors:
Adrián I. Löffler, MD, Jamieson M. Bourque, MD, MHS
Published in:
Journal of Nuclear Cardiology
|
Issue 5/2016
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Excerpt
Single-photon emission-computed tomographic (SPECT) myocardial perfusion imaging (MPI) has incremental diagnostic and prognostic value over exercise stress electrocardiography, and the assessment of transient ischemic dilation (TID) is a key contributor to its ability to detect higher risk patients. The diagnostic and prognostic role of TID has been evaluated extensively in those undergoing exercise MPI.
1,
2 However, approximately 50% of the ~10 million MPI studies performed annually in the US undergo pharmacologic MPI,
3 the majority receiving regadenoson for vasodilator stress due to its improved tolerability by patients, safety profile, and ease of administration.
4 Given the high prevalence of this testing, the significance of TID in this population is of high importance. The diagnostic role of TID in regadenoson MPI has been assessed previously, but the prognostic impact has not determined. …