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Journal of Nuclear Cardiology
Published in: Journal of Nuclear Cardiology 6/2015

01-12-2015 | Debate Article

Screening asymptomatic patients with type 2 diabetes is recommended: Pro

Authors: Mario Petretta, MD, Alberto Cuocolo, MD

Published in: Journal of Nuclear Cardiology | Issue 6/2015

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Excerpt

Cardiovascular morbidity is common in type 2 diabetes mellitus (DM) and several epidemiological studies reported that DM is associated with a marked increase in the risk of coronary artery disease (CAD).1 In 1999, the Finnish diabetologist, Yki-Järvinen, provocatively stated: “diabetes is a cardiovascular disease which you diagnose by measuring the blood glucose.”2 In the same year, also the American Heart Association stated that it might be appropriate to say “diabetes is a cardiovascular disease.”3 At this time, DM is commonly considered as a CAD risk equivalent in many position papers and guidelines.4 However, screening asymptomatic DM subjects for detection of CAD and subsequent management remains controversial.5 …
Literature
1.
2.
Torp-Pedersen C, Jeppesen J. Diabetes and hypertension and atherosclerotic cardiovascular disease: Related or separate entities often found together. Hypertension 2011;57:887-8.CrossRefPubMed
3.
Grundy SM, Benjamin IJ, Burke GL, Chait A, Eckel RH, Howard BV, et al. Diabetes and cardiovascular disease: A statement for healthcare professionals from the American Heart Association. Circulation 1999;100:1134-46.CrossRefPubMed
4.
Kavousi M, Leening MJ, Nanchen D, Greenland P, Graham IM, Steyerberg EW, et al. Comparison of application of the ACC/AHA guidelines, Adult Treatment Panel III guidelines, and European Society of Cardiology guidelines for cardiovascular disease prevention in a European cohort. JAMA 2014;311:1416-23.CrossRefPubMed
5.
Hage FG, Iskandrian AE. Cardiovascular imaging in diabetes mellitus. J Nucl Cardiol 2011;18:959-65.CrossRefPubMed
6.
Wackers FJ, Young LH, Inzucchi SE, Chyun DA, Davey JA, Barrett EJ, et al. Detection of Ischemia in Asymptomatic Diabetics Investigators. Detection of silent myocardial ischemia in asymptomatic diabetic subjects: The DIAD study. Diabetes Care 2004;27:1954-61.CrossRefPubMed
7.
May O, Arildsen H, Damsgaard EM, Mickley H. Prevalence and prediction of silent ischaemia in diabetes mellitus: A population-based study. Cardiovasc Res 1997;34:241-7.CrossRefPubMed
8.
Moralidis E, Didangelos T, Arsos G, Athyros V, Mikhailidis DP. Myocardial perfusion scintigraphy in asymptomatic diabetic patients: A critical review. Diabetes Metab Res Rev 2010;26:336-47.CrossRefPubMed
9.
Wackers FJ, Young LH. Lessons learned from the detection of ischemia in asymptomatic diabetics (DIAD) study. J Nucl Cardiol 2009;16:855-9.CrossRefPubMed
10.
American Diabetes Association. Standards of medical care in diabetes—2014. Diabetes Care 2014;37:S14-80.CrossRef
11.
Rydén L, Grant PJ, Anker SD, Berne C, Cosentino F, Danchin N, et al. ESC Guidelines on diabetes, pre-diabetes, and cardiovascular diseases developed in collaboration with the EASD: The Task Force on diabetes, pre-diabetes, and cardiovascular diseases of the European Society of Cardiology (ESC) and developed in collaboration with the European Association for the Study of Diabetes (EASD). Eur Heart J 2013;34:3035-87.CrossRefPubMed
12.
Acampa W, Petretta M, Evangelista L, Daniele S, Xhoxhi E, De Rimini ML, et al. Myocardial perfusion imaging and risk classification for coronary heart disease in diabetic patients. The IDIS study: A prospective, multicentre trial. Eur J Nucl Med Mol Imaging 2012;39:387-95.CrossRefPubMed
13.
Miller TD, Redberg RF, Wackers FJ. Screening asymptomatic diabetic patients for coronary artery disease: Why not? J Am Coll Cardiol 2006;48:761-4.CrossRefPubMed
14.
Acampa W, Petretta M, Daniele S, Del Prete G, Assante R, Zampella E, et al. Incremental prognostic value of stress myocardial perfusion imaging in asymptomatic diabetic patients. Atherosclerosis 2013;227:307-12.CrossRefPubMed
15.
Zhang L, Li H, Zhang S, Jaacks LM, Li Y, Ji L. Silent myocardial ischemia detected by single photon emission computed tomography (SPECT) and risk of cardiac events among asymptomatic patients with type 2 diabetes: A meta-analysis of prospective studies. J Diabetes Complications 2014;28:413-8.CrossRefPubMed
16.
Acampa W, Cantoni V, Green R, Maio F, Daniele S, Nappi C, et al. Prognostic value of normal stress myocardial perfusion imaging in diabetic patients: A meta-analysis. J Nucl Cardiol 2014;21:893-902.CrossRefPubMed
17.
Petretta M, Acampa W, Evangelista L, Daniele S, Zampella E, Assante R, et al. Reclassification of cardiovascular risk by myocardial perfusion imaging in diabetic patients with abnormal resting electrocardiogram. Nutr Metab Cardiovasc Dis 2014;24:588-93.CrossRefPubMed
18.
Zellweger MJ, Maraun M, Osterhues HH, Keller U, Müller-Brand J, Jeger R, et al. Progression to overt or silent cad in asymptomatic patients with diabetes mellitus at high coronary risk: Main findings of the prospective multicenter BARDOT trial with a pilot randomized treatment substudy. JACC Cardiovasc Imaging 2014;7:1001-10.CrossRefPubMed
19.
Lièvre MM, Moulin P, Thivolet C, Rodier M, Rigalleau V, Penfornis A, et al. DYNAMIT investigators. Detection of silent myocardial ischemia in asymptomatic patients with diabetes: Results of a randomized trial and meta-analysis assessing the effectiveness of systematic screening. Trials 2011;12:23.PubMedCentralCrossRefPubMed
20.
McCullough PA, Fazel P, Choi JW. Screening, Diagnosis, and management of CAD in asymptomatic diabetic patients. JACC Cardiovasc Imaging 2014;7:1011-2.CrossRefPubMed
Metadata
Title
Screening asymptomatic patients with type 2 diabetes is recommended: Pro
Authors
Mario Petretta, MD
Alberto Cuocolo, MD
Publication date
01-12-2015
Publisher
Springer US
Published in
Journal of Nuclear Cardiology / Issue 6/2015
Print ISSN: 1071-3581
Electronic ISSN: 1532-6551
DOI
https://doi.org/10.1007/s12350-015-0250-0

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