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01-02-2015 | Original Article

Warranty periods for normal myocardial perfusion stress SPECT

Authors: Guillermo Romero-Farina, MD, PhD, FESC, FASNC, Jaume Candell-Riera, MD, PhD, FESC, Santiago Aguadé-Bruix, MD, Ignacio Ferreira-González, MD, PhD, Gemma Cuberas-Borrós, BSc, Nazarena Pizzi, MD, David García-Dorado, MD, PhD, FACC, FESC

Published in: Journal of Nuclear Cardiology | Issue 1/2015

Abstract

Background

To assess different warranty periods following a normal myocardial perfusion SPECT based on patients’ clinical characteristics and the type of stress performed.

Methods and Results

A study was done of 2,922 consecutive patients (62.9 ± 13 years; 53.4% women) with a normal stress-rest SPECT. The warranty period was defined as the period during which patients remained at a low risk (<1% events/year) of total mortality (TM), or hard events (HE) (cardiac death or non-fatal myocardial infarction). Of these patients, 2,051 were given an exercise myocardial perfusion imaging (Ex-MPI); 461 submaximal exercise plus dipyridamole (Ex+Dipy-MPI); and 410 dipyridamole (Dipy-MPI). During a mean follow-up of 5 ± 3.3 years, a significant reduction (P < .05) of the warranty period for TM (13.5, 9.6 and 8 months) and HE (34.8, 20.5 and 8.2 months) was observed, for Ex-MPI, Ex+Dipy-MPI and Dipy-MPI, respectively. Other warranty period determinants were the clinical variables of age, sex, diabetes and known coronary artery disease. An abnormal left ventricular ejection fraction on gated-SPECT also significantly shortened the warranty period for HE in patients undergoing Ex+Dipy-MPI (P = .001) or Dipy-MPI alone (P = .007).

Conclusions

The warranty period for a normal stress-rest SPECT is highly variable since it is primarily determined by the type of stress, the patient’s clinical characteristics and LVEF.

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Title: Warranty periods for normal myocardial perfusion stress SPECT
Authors: Guillermo Romero-Farina, MD, PhD, FESC, FASNC
Jaume Candell-Riera, MD, PhD, FESC
Santiago Aguadé-Bruix, MD
Ignacio Ferreira-González, MD, PhD
Gemma Cuberas-Borrós, BSc
Nazarena Pizzi, MD
David García-Dorado, MD, PhD, FACC, FESC
Publication date: 01-02-2015
Publisher: Springer US
Published in: Journal of Nuclear Cardiology / Issue 1/2015
Print ISSN: 1071-3581
Electronic ISSN: 1532-6551
DOI: https://doi.org/10.1007/s12350-014-9957-6

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Warranty periods for normal myocardial perfusion stress SPECT

Abstract

Background

Methods and Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods and Results

Conclusions

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