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01-02-2015 | Editorial

Variability in normal myocardial blood flow measurements: Physiologic, methodologic, or protocol related?

Authors: Timothy M. Bateman, MD, James A. Case, PhD

Published in: Journal of Nuclear Cardiology | Issue 1/2015

Excerpt

The current issue of the Journal of Nuclear Cardiology includes an interesting investigation that studied 3 software approaches for quantitating myocardial blood flow (MBF) and MBF reserve (MBFR) in 49 subjects who met multiple criteria for having normal cardiovascular physiology: able to exercise to a high level without chest pain or ischemic end-points, no major risk factors, and normal rubidium-82 myocardial perfusion images.1 The study found that these important flow measurements in apparently normal subjects varied substantially according to age, gender, coronary territory, and software employed. The results raise legitimate questions about whether positron emission tomography (PET) derived flow quantitation is currently sufficiently mature for inclusion in clinical imaging reports that might influence subsequent patient care. …

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Title: Variability in normal myocardial blood flow measurements: Physiologic, methodologic, or protocol related?
Authors: Timothy M. Bateman, MD
James A. Case, PhD
Publication date: 01-02-2015
Publisher: Springer US
Published in: Journal of Nuclear Cardiology / Issue 1/2015
Print ISSN: 1071-3581
Electronic ISSN: 1532-6551
DOI: https://doi.org/10.1007/s12350-014-0007-1

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