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Journal of Ophthalmic Inflammation and Infection

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Open Access 01-09-2011 | Brief Report

Ocular modifications in a young girl with cryopyrin-associated periodic syndromes responding to interleukin-1 receptor antagonist anakinra

Authors: Celine Terrada, Benedicte Neven, Nathalie Boddaert, Eric H Souied, Anne Marie Prieur, Pierre Quartier, Phuc Lehoang, Bahram Bodaghi

Published in: Journal of Ophthalmic Inflammation and Infection | Issue 3/2011

Abstract

An 8-year-old patient with genetically confirmed chronic infantile neurological cutaneous and articular syndrome was treated with interleukin-1 receptor antagonist, anakinra. She initially presented with recurrent episodes of fever, rash, chronic fatigue, frequent headaches, ocular involvement (corneal infiltrate and papillary edema), and permanent increased biologic inflammatory markers. Following treatment with anakinra, all symptoms and inflammation resolved. Ophthalmologic signs normalized. This ophthalmologic description (optic nerve and cornea) has never been illustrated, even if ocular affections are classic in the cryopyrin-associated periodic syndromes.

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Title: Ocular modifications in a young girl with cryopyrin-associated periodic syndromes responding to interleukin-1 receptor antagonist anakinra
Authors: Celine Terrada
Benedicte Neven
Nathalie Boddaert
Eric H Souied
Anne Marie Prieur
Pierre Quartier
Phuc Lehoang
Bahram Bodaghi
Publication date: 01-09-2011
Publisher: Springer Berlin Heidelberg
Published in: Journal of Ophthalmic Inflammation and Infection / Issue 3/2011
Electronic ISSN: 1869-5760
DOI: https://doi.org/10.1007/s12348-010-0018-2

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Ocular modifications in a young girl with cryopyrin-associated periodic syndromes responding to interleukin-1 receptor antagonist anakinra

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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