Skip to main content
Top
Published in: Breast Cancer 5/2023

12-06-2023 | Mastectomy | Original Article

What affects women’s decision-making on breast reconstruction after mastectomy for breast cancer?

Authors: Sara van Bekkum, Marloes E. Clarijs, Fientje J. C. van der Veen, Joost van Rosmalen, Linetta B. Koppert, Marian B. E. Menke-Pluijmers

Published in: Breast Cancer | Issue 5/2023

Login to get access

Abstract

Purpose

To establish the breast reconstruction rate in a large Dutch teaching hospital, and to gain insight into the motives of women to opt for or reject post-mastectomy breast reconstruction.

Methods

In a retrospective, cross-sectional study, all consecutive patients who underwent mastectomy for invasive breast cancer or ductal carcinoma in situ (DCIS) were identified and categorized into two groups based on subsequent breast reconstruction or not. Patient-reported outcomes were assessed with the validated Breast-Q and a short survey about the decision-making process in breast reconstruction. These outcomes were compared between the two groups using univariable analyses, multivariable logistic regression, and multiple linear regression analyses. The Breast-Q scores were also compared to Dutch normative values.

Results

A total of 319 patients were identified of whom 68% had no breast reconstruction. Of the 102 patients with breast reconstruction, the majority (93%) received immediate, instead of delayed breast reconstruction. The survey was completed by 155 (49%) patients. The non-reconstruction group, on average, reported significantly poorer psychosocial well-being, compared to the reconstruction group as well as compared to the normative data. However, the majority of the non-reconstruction group (83%) stated that they had no desire for breast reconstruction. In both groups, most patients stated that the provided information was sufficient.

Conclusion

Patients have personal motives to opt for or reject breast reconstruction. It seemed that patients differ in their rating of values that affect their decision since the same arguments were used to opt for or reject reconstruction. Notably, patients were well-informed in their decision making.
Literature
1.
go back to reference Howard-McNatt MM. Patients opting for breast reconstruction following mastectomy: an analysis of uptake rates and benefit. Breast Cancer Targets Ther. 2013;5:9–15. Howard-McNatt MM. Patients opting for breast reconstruction following mastectomy: an analysis of uptake rates and benefit. Breast Cancer Targets Ther. 2013;5:9–15.
3.
go back to reference van Maaren MC, de Munck L, de Bock GH, et al. 10 year survival after breast-conserving surgery plus radiotherapy compared with mastectomy in early breast cancer in the Netherlands: a population-based study. Lancet Oncol. 2016;17(8):1158–70. CrossRefPubMed van Maaren MC, de Munck L, de Bock GH, et al. 10 year survival after breast-conserving surgery plus radiotherapy compared with mastectomy in early breast cancer in the Netherlands: a population-based study. Lancet Oncol. 2016;17(8):1158–70. CrossRefPubMed
4.
go back to reference Winters ZE, Benson JR, Pusic AL. A systematic review of the clinical evidence to guide treatment recommendations in breast reconstruction based on patient-reported outcome measures and health-related quality of life. Ann Surg. 2010;252(6):929–42. CrossRefPubMed Winters ZE, Benson JR, Pusic AL. A systematic review of the clinical evidence to guide treatment recommendations in breast reconstruction based on patient-reported outcome measures and health-related quality of life. Ann Surg. 2010;252(6):929–42. CrossRefPubMed
5.
go back to reference Lagendijk M, van Egdom LSE, van Veen FEE, et al. Patient-reported outcome measures may add value in breast cancer surgery. Ann Surg Oncol. 2018;25:3563–71.CrossRefPubMed Lagendijk M, van Egdom LSE, van Veen FEE, et al. Patient-reported outcome measures may add value in breast cancer surgery. Ann Surg Oncol. 2018;25:3563–71.CrossRefPubMed
6.
go back to reference van Bommel ACM, Mureau MAM, Schreuder K, et al. Large variation between hospitals in immediate breast reconstruction rates after mastectomy for breast cancer in the Netherlands. J Plast Reconstr Aesthetic Surg. 2017;70:215–21.CrossRef van Bommel ACM, Mureau MAM, Schreuder K, et al. Large variation between hospitals in immediate breast reconstruction rates after mastectomy for breast cancer in the Netherlands. J Plast Reconstr Aesthetic Surg. 2017;70:215–21.CrossRef
8.
go back to reference Fang SY, Shu BC, Chang YJ. The effect of breast reconstruction surgery on body image among women after mastectomy: a meta-analysis. Breast Cancer Res Treat. 2013;137(1):13–21.CrossRefPubMed Fang SY, Shu BC, Chang YJ. The effect of breast reconstruction surgery on body image among women after mastectomy: a meta-analysis. Breast Cancer Res Treat. 2013;137(1):13–21.CrossRefPubMed
9.
go back to reference Retrouvey H, Kerrebijn I, Metcalfe KA, et al. Psychosocial functioning in women with early breast cancer treated with breast surgery with or without immediate breast reconstruction. Ann Surg Oncol. 2019;26:2444–51.CrossRefPubMed Retrouvey H, Kerrebijn I, Metcalfe KA, et al. Psychosocial functioning in women with early breast cancer treated with breast surgery with or without immediate breast reconstruction. Ann Surg Oncol. 2019;26:2444–51.CrossRefPubMed
10.
go back to reference D’Souza N, Darmanin G, Fedorowicz Z. Immediate versus delayed reconstruction following surgery for breast cancer. Cochrane Database Syst Rev. 2011;2011(7):CD008674. D’Souza N, Darmanin G, Fedorowicz Z. Immediate versus delayed reconstruction following surgery for breast cancer. Cochrane Database Syst Rev. 2011;2011(7):CD008674.
11.
go back to reference van Bommel ACM, de Ligt KM, Schreuder K, et al. The added value of immediate breast reconstruction to health-related quality of life of breast cancer patients. Eur J Surg Oncol. 2020;46(10):1848–53.CrossRefPubMed van Bommel ACM, de Ligt KM, Schreuder K, et al. The added value of immediate breast reconstruction to health-related quality of life of breast cancer patients. Eur J Surg Oncol. 2020;46(10):1848–53.CrossRefPubMed
12.
go back to reference Kouwenberg CAE, De Ligt KM, Kranenburg LW, et al. Long-term health-related quality of life after four common surgical treatment options for breast cancer and the effect of complications: a retrospective patient-reported survey among 1871 patients. Plast Reconstr Surg. 2020;146(1):1–13.CrossRefPubMed Kouwenberg CAE, De Ligt KM, Kranenburg LW, et al. Long-term health-related quality of life after four common surgical treatment options for breast cancer and the effect of complications: a retrospective patient-reported survey among 1871 patients. Plast Reconstr Surg. 2020;146(1):1–13.CrossRefPubMed
14.
go back to reference de Ligt KM, van Bommel ACM, Schreuder K, et al. The effect of being informed on receiving immediate breast reconstruction in breast cancer patients. Eur J Surg Oncol. 2018;44(5):717–24.CrossRefPubMed de Ligt KM, van Bommel ACM, Schreuder K, et al. The effect of being informed on receiving immediate breast reconstruction in breast cancer patients. Eur J Surg Oncol. 2018;44(5):717–24.CrossRefPubMed
15.
go back to reference Flitcroft K, Brennan M, Spillane A. Making decisions about breast reconstruction: a systematic review of patient-reported factors influencing choice. Qual Life Res. 2017;26:2287–319.CrossRefPubMed Flitcroft K, Brennan M, Spillane A. Making decisions about breast reconstruction: a systematic review of patient-reported factors influencing choice. Qual Life Res. 2017;26:2287–319.CrossRefPubMed
16.
go back to reference van Bommel A, Spronk P, Mureau M, et al. Breast-contour-preserving procedure as a multidisciplinary parameter of esthetic outcome in breast cancer treatment in the Netherlands. Ann Surg Oncol. 2019;26:1704–11.CrossRefPubMedPubMedCentral van Bommel A, Spronk P, Mureau M, et al. Breast-contour-preserving procedure as a multidisciplinary parameter of esthetic outcome in breast cancer treatment in the Netherlands. Ann Surg Oncol. 2019;26:1704–11.CrossRefPubMedPubMedCentral
17.
go back to reference Zielinski T, Lorenc-Podgorska K, Antoszewski B, Why women who have mastectomy decide not to have breast reconstruction? Pol Przegl Chir. 2014;86(10):451–5. Zielinski T, Lorenc-Podgorska K, Antoszewski B, Why women who have mastectomy decide not to have breast reconstruction? Pol Przegl Chir. 2014;86(10):451–5.
18.
go back to reference Héquet D, Zarca K, Dolbeault S, et al. Reasons of not having breast reconstruction: a historical cohort of 1937 breast cancer patients undergoing mastectomy. Springerplus. 2013;2:325. Héquet D, Zarca K, Dolbeault S, et al. Reasons of not having breast reconstruction: a historical cohort of 1937 breast cancer patients undergoing mastectomy. Springerplus. 2013;2:325.
19.
go back to reference Handel N, Silverstein MJ, Waisman E, Waisman JR. Reasons why mastectomy patients do not have breast reconstruction. Plast Reconstr Surg. 1990;86(6):1118–22.CrossRefPubMed Handel N, Silverstein MJ, Waisman E, Waisman JR. Reasons why mastectomy patients do not have breast reconstruction. Plast Reconstr Surg. 1990;86(6):1118–22.CrossRefPubMed
20.
go back to reference Ananian P, Houvenaeghel G, Protière C, et al. Determinants of patients’ choice of reconstruction with mastectomy for primary breast cancer. Ann Surg Oncol. 2004;11(8):762–71.CrossRefPubMed Ananian P, Houvenaeghel G, Protière C, et al. Determinants of patients’ choice of reconstruction with mastectomy for primary breast cancer. Ann Surg Oncol. 2004;11(8):762–71.CrossRefPubMed
21.
go back to reference Brennan ME, Spillane AJ. Uptake and predictors of post-mastectomy reconstruction in women with breast malignancy—systematic review. Eur J Surg Oncol. 2013;39(6):527–41.CrossRefPubMed Brennan ME, Spillane AJ. Uptake and predictors of post-mastectomy reconstruction in women with breast malignancy—systematic review. Eur J Surg Oncol. 2013;39(6):527–41.CrossRefPubMed
23.
go back to reference Cano SJ, Klassen AF, Scott AM, Cordeiro PG, Pusic AL. The BREAST-Q: further validation in independent clinical samples. Plast Reconstr Surg. 2012;129(2):293–302.CrossRefPubMed Cano SJ, Klassen AF, Scott AM, Cordeiro PG, Pusic AL. The BREAST-Q: further validation in independent clinical samples. Plast Reconstr Surg. 2012;129(2):293–302.CrossRefPubMed
24.
go back to reference Pusic AL, Klassen AF, Scott AM, Klok JA, Cordeiro PG, Cano SJ. Development of a new patient-reported outcome measure for breast surgery: the BREAST-Q. Plast Reconstr Surg. 2009;142(2):345–53.CrossRef Pusic AL, Klassen AF, Scott AM, Klok JA, Cordeiro PG, Cano SJ. Development of a new patient-reported outcome measure for breast surgery: the BREAST-Q. Plast Reconstr Surg. 2009;142(2):345–53.CrossRef
25.
go back to reference Metcalfe KA, Semple J, Quan ML, et al. Why some mastectomy patients Opt to undergo delayed breast reconstruction: results of a long-term prospective study. Plast Reconstr Surg. 2017;139(2):267–75.CrossRefPubMed Metcalfe KA, Semple J, Quan ML, et al. Why some mastectomy patients Opt to undergo delayed breast reconstruction: results of a long-term prospective study. Plast Reconstr Surg. 2017;139(2):267–75.CrossRefPubMed
26.
go back to reference Molenaar S, Oort F, Sprangers M, et al. Predictors of patients’ choices for breast-conserving therapy or mastectomy: a prospective study. Br J Cancer. 2004;90(11):2123–30.CrossRefPubMedPubMedCentral Molenaar S, Oort F, Sprangers M, et al. Predictors of patients’ choices for breast-conserving therapy or mastectomy: a prospective study. Br J Cancer. 2004;90(11):2123–30.CrossRefPubMedPubMedCentral
27.
go back to reference Oemrawsingh A, Clarijs M, Pusic A, et al. BREAST-Q breast-conserving therapy module: normative data from a Dutch sample of 9059 women. Plast Reconstr Surg. 2022;150(5):985–93.CrossRefPubMedPubMedCentral Oemrawsingh A, Clarijs M, Pusic A, et al. BREAST-Q breast-conserving therapy module: normative data from a Dutch sample of 9059 women. Plast Reconstr Surg. 2022;150(5):985–93.CrossRefPubMedPubMedCentral
29.
go back to reference Yoon AP, Qi J, Brown DL, et al. Outcomes of immediate versus delayed breast reconstruction: results of a multicenter prospective study. Breast. 2018;37:72–9.CrossRefPubMed Yoon AP, Qi J, Brown DL, et al. Outcomes of immediate versus delayed breast reconstruction: results of a multicenter prospective study. Breast. 2018;37:72–9.CrossRefPubMed
30.
go back to reference Ricci JA, Epstein S, Momoh AO, Lin SJ, Singhal D, Lee BT. A meta-analysis of implant-based breast reconstruction and timing of adjuvant radiation therapy. J Surg Res. 2017;218:108–16.CrossRefPubMed Ricci JA, Epstein S, Momoh AO, Lin SJ, Singhal D, Lee BT. A meta-analysis of implant-based breast reconstruction and timing of adjuvant radiation therapy. J Surg Res. 2017;218:108–16.CrossRefPubMed
31.
go back to reference Lam TC, Hsieh F, Boyages J. The effects of postmastectomy adjuvant radiotherapy on immediate two-stage prosthetic breast reconstruction: a systematic review. Plast Reconstr Surg. 2013;132:511–8.CrossRefPubMed Lam TC, Hsieh F, Boyages J. The effects of postmastectomy adjuvant radiotherapy on immediate two-stage prosthetic breast reconstruction: a systematic review. Plast Reconstr Surg. 2013;132:511–8.CrossRefPubMed
Metadata
Title
What affects women’s decision-making on breast reconstruction after mastectomy for breast cancer?
Authors
Sara van Bekkum
Marloes E. Clarijs
Fientje J. C. van der Veen
Joost van Rosmalen
Linetta B. Koppert
Marian B. E. Menke-Pluijmers
Publication date
12-06-2023
Publisher
Springer Nature Singapore
Published in
Breast Cancer / Issue 5/2023
Print ISSN: 1340-6868
Electronic ISSN: 1880-4233
DOI
https://doi.org/10.1007/s12282-023-01471-4

Other articles of this Issue 5/2023

Breast Cancer 5/2023 Go to the issue
Webinar | 19-02-2024 | 17:30 (CET)

Keynote webinar | Spotlight on antibody–drug conjugates in cancer

Antibody–drug conjugates (ADCs) are novel agents that have shown promise across multiple tumor types. Explore the current landscape of ADCs in breast and lung cancer with our experts, and gain insights into the mechanism of action, key clinical trials data, existing challenges, and future directions.

Dr. Véronique Diéras
Prof. Fabrice Barlesi
Developed by: Springer Medicine