Skip to main content
Top
Published in: Breast Cancer 1/2013

01-01-2013 | Special Feature

Comprehensive ultrasound diagnosis for intraductal spread of primary breast cancer

Authors: Kazutaka Nakashima, Takuya Moriya

Published in: Breast Cancer | Issue 1/2013

Login to get access

Abstract

Background

The current capacity of preoperative ultrasound examinations to estimate the intraductal spread of primary breast cancer was evaluated. The current ultrasound examination has three modes, B-mode, vascularity, and elastography, and this study evaluated this comprehensive ultrasound examination.

Methods

Of the patients undergoing breast cancer surgery for a breast mass at our department between April 2010 and March 2011, we evaluated 99 in whom breast-conserving surgery was scheduled, and performed preoperative ultrasounds and stored the digital ultrasound images and pathology data. ACR BI-RADS®-US lexicon elastography for the main mass and peri-tumoral ductal lesions (PTDL, defined in main sentence), and the vascularity and elasticity pattern (defined in main sentence) were evaluated.

Results

A cut end-negative resection at the first procedure after ultrasound estimation was achieved in 76.7%, and the breast was conserved by an additional resection with a negative margin in 90.6%. Shadowing of mass posterior acoustic features tends to indicate cut end-negative results significantly. There was a statistical difference between “vascularity in PTDL” and “elasticity pattern of PTDL”.

Conclusion

Using the recent comprehensive ultrasound examination with vascularity and elastography was useful for the preoperative estimation of intraductal spread of primary breast cancer in our retrospective study.
Literature
1.
go back to reference Japanese Breast Cancer Society (JBCS). General rules for clinical and pathological recording of breast cancer. 16th ed. 2008. Japanese Breast Cancer Society (JBCS). General rules for clinical and pathological recording of breast cancer. 16th ed. 2008.
2.
go back to reference American College of Radiology (ACR). Breast Imaging Reporting and Data System Atlas (BI-RADS® Atlas). 2nd ed. 2003. American College of Radiology (ACR). Breast Imaging Reporting and Data System Atlas (BI-RADS® Atlas). 2nd ed. 2003.
3.
go back to reference Cho N, Moon WK, Kim YH, Charg JM, Park SH, Lyou CY. Sonoelastographic strain index for differentiation of benign and malignant nonpalpable breast masses. J Ultrasound Med. 2010;29(1):1–7.PubMed Cho N, Moon WK, Kim YH, Charg JM, Park SH, Lyou CY. Sonoelastographic strain index for differentiation of benign and malignant nonpalpable breast masses. J Ultrasound Med. 2010;29(1):1–7.PubMed
4.
go back to reference Itoh A, Ueno E, Tohno E, Shiina T, Yamakawa M, Matsumura T, et al. Breast disease, clinical application of US elastography for diagnosis. Radiology. 2006;239(2):341–50. Itoh A, Ueno E, Tohno E, Shiina T, Yamakawa M, Matsumura T, et al. Breast disease, clinical application of US elastography for diagnosis. Radiology. 2006;239(2):341–50.
5.
go back to reference Charfare H, MacLatchie E, Cordier C, Bradley M, Eadie C, Byrtus A, et al. A Comparison of different methods of assessing cosmetic outcome following breast conserving surgery and factors influencing cosmetic outcome. BJMP. 2010;3(1):310. Charfare H, MacLatchie E, Cordier C, Bradley M, Eadie C, Byrtus A, et al. A Comparison of different methods of assessing cosmetic outcome following breast conserving surgery and factors influencing cosmetic outcome. BJMP. 2010;3(1):310.
6.
go back to reference Japanese Breast Cancer Society (JBCS). Clinical practice guidelines for breast cancer: part of epidemiology and diagnosis. 2011 ed. 2011. Japanese Breast Cancer Society (JBCS). Clinical practice guidelines for breast cancer: part of epidemiology and diagnosis. 2011 ed. 2011.
7.
go back to reference Tohno E, Takahashi H, Tamada T, Fujimoto Y, Yasuda H, Ohuchi N. Educational program and testing using images for the standardization of breast cancer screening by ultrasonography. Breast Cancer. 2010. doi:10.1007/s12282-010-0221-x.PubMed Tohno E, Takahashi H, Tamada T, Fujimoto Y, Yasuda H, Ohuchi N. Educational program and testing using images for the standardization of breast cancer screening by ultrasonography. Breast Cancer. 2010. doi:10.​1007/​s12282-010-0221-x.PubMed
8.
go back to reference Chang JM, Moon WK, Cho N, Kim SJ. Breast mass evaluation: factors influencing the quality of US elastography. Radiology. 2011;258(3). Chang JM, Moon WK, Cho N, Kim SJ. Breast mass evaluation: factors influencing the quality of US elastography. Radiology. 2011;258(3).
9.
go back to reference Raza S, Odulate A, Ong EMW, Chikarmane S, Harston CW. Using real-time tissue elastography for breast lesion evaluation. J Ultrasound Med. 2010;29(4):551–63.PubMed Raza S, Odulate A, Ong EMW, Chikarmane S, Harston CW. Using real-time tissue elastography for breast lesion evaluation. J Ultrasound Med. 2010;29(4):551–63.PubMed
10.
go back to reference Leong LCH, Sim LSJ, Lee YS, Ng FC, Wan CM, Fook-Chong SMC, et al. A prospective study to compare the diagnostic performance of breast elastography versus conventional breast ultrasound. Clin Radiol. 2010;65(11):887–94.PubMedCrossRef Leong LCH, Sim LSJ, Lee YS, Ng FC, Wan CM, Fook-Chong SMC, et al. A prospective study to compare the diagnostic performance of breast elastography versus conventional breast ultrasound. Clin Radiol. 2010;65(11):887–94.PubMedCrossRef
11.
go back to reference Tibor T. Breast cancer: a lobar disease, 2010. Tibor T. Breast cancer: a lobar disease, 2010.
Metadata
Title
Comprehensive ultrasound diagnosis for intraductal spread of primary breast cancer
Authors
Kazutaka Nakashima
Takuya Moriya
Publication date
01-01-2013
Publisher
Springer Japan
Published in
Breast Cancer / Issue 1/2013
Print ISSN: 1340-6868
Electronic ISSN: 1880-4233
DOI
https://doi.org/10.1007/s12282-011-0326-x

Other articles of this Issue 1/2013

Breast Cancer 1/2013 Go to the issue
Webinar | 19-02-2024 | 17:30 (CET)

Keynote webinar | Spotlight on antibody–drug conjugates in cancer

Antibody–drug conjugates (ADCs) are novel agents that have shown promise across multiple tumor types. Explore the current landscape of ADCs in breast and lung cancer with our experts, and gain insights into the mechanism of action, key clinical trials data, existing challenges, and future directions.

Dr. Véronique Diéras
Prof. Fabrice Barlesi
Developed by: Springer Medicine