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Published in: Indian Journal of Surgery 1/2013

01-06-2013 | Case Report

Omental Gangrene and Porto-Mesenteric Thrombosis in a Patient of Protein C and Protein S Deficiency

Authors: Nirmal M. Patle, Om Tantia, Prakhar Chandra Das, Jayanta Mukherjee, Parmanand Prasad

Published in: Indian Journal of Surgery | Special Issue 1/2013

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Abstract

Omental gangrene is an infrequent cause of acute abdomen with unclear etiology. Hypercoagualable states like protein C or protein S deficiency have never been implicated in the etiology of omental gangrene. We present this case report of a patient having protein C and protein S deficiency presenting with omental gangrene and extensive porto mesenteric thrombosis.
Literature
1.
go back to reference Caprini JA, Glase CJ, Anderson CB, Hathaway K (2004) Laboratory markers in the diagnosis of venous thromboembolism. Circulation 109(suppl):I-4–I-8CrossRef Caprini JA, Glase CJ, Anderson CB, Hathaway K (2004) Laboratory markers in the diagnosis of venous thromboembolism. Circulation 109(suppl):I-4–I-8CrossRef
2.
go back to reference Cho YP, Kwon T-W, Ahn J-H, Kang GH, Han MS, Kim YH, Kwak JH, Lee SG (2005) Protein C and/or S deficiency presenting as peripheral arterial insufficiency. Br J Radiol 78:601–605PubMedCrossRef Cho YP, Kwon T-W, Ahn J-H, Kang GH, Han MS, Kim YH, Kwak JH, Lee SG (2005) Protein C and/or S deficiency presenting as peripheral arterial insufficiency. Br J Radiol 78:601–605PubMedCrossRef
3.
go back to reference Koster T, Rosendaal FR, Briet E et al (1995) Protein C deficiency in a controlled series of unselected outpatients: an infrequent but clear risk factor for venous thrombosis (Leiden Thrombophilia Study). Blood 85(10):2756–2761PubMed Koster T, Rosendaal FR, Briet E et al (1995) Protein C deficiency in a controlled series of unselected outpatients: an infrequent but clear risk factor for venous thrombosis (Leiden Thrombophilia Study). Blood 85(10):2756–2761PubMed
4.
go back to reference Pabinger I, Schneider B (1996) For the Gesellschaft fur Thrombose- und Hamostaseforschung (GTH) Study Group on Natural Inhibitors. Thrombotic risk in hereditary antithrombin III, protein C, or protein S deficiency. A cooperative, retrospective study. Arterioscler Thromb Vasc Biol 16(6):742–748PubMedCrossRef Pabinger I, Schneider B (1996) For the Gesellschaft fur Thrombose- und Hamostaseforschung (GTH) Study Group on Natural Inhibitors. Thrombotic risk in hereditary antithrombin III, protein C, or protein S deficiency. A cooperative, retrospective study. Arterioscler Thromb Vasc Biol 16(6):742–748PubMedCrossRef
5.
go back to reference Kohler J, Kasper J, Wett I, von Reutern GM (1990) Ischemic stroke due to protein C deficiency. Stroke 21:1077–1080PubMedCrossRef Kohler J, Kasper J, Wett I, von Reutern GM (1990) Ischemic stroke due to protein C deficiency. Stroke 21:1077–1080PubMedCrossRef
6.
go back to reference De Stefano V, Leone G, Micalizzi P, Teofili L, Falappa PG, Pollari G et al (1991) Arterial thrombosis as clinical manifestation of congenital protein C deficiency. Ann Hematol 62:180–183PubMedCrossRef De Stefano V, Leone G, Micalizzi P, Teofili L, Falappa PG, Pollari G et al (1991) Arterial thrombosis as clinical manifestation of congenital protein C deficiency. Ann Hematol 62:180–183PubMedCrossRef
7.
go back to reference Kario K, Matsuo T, Tai S, Sakamoto S, Yamada T, Miki T et al (1992) Congenital protein C deficiency and myocardial infarction: concomitant factor VII hyperactivity may play a role in the onset of arterial thrombosis. Thromb Res 67:95–103PubMedCrossRef Kario K, Matsuo T, Tai S, Sakamoto S, Yamada T, Miki T et al (1992) Congenital protein C deficiency and myocardial infarction: concomitant factor VII hyperactivity may play a role in the onset of arterial thrombosis. Thromb Res 67:95–103PubMedCrossRef
8.
go back to reference Sasmal PK, Tantia O, Patle N, Khanna S (2010) Omental torsion and infarction: a diagnostic dilemma and its laparoscopic management. JLAST 20(3):225–229 Sasmal PK, Tantia O, Patle N, Khanna S (2010) Omental torsion and infarction: a diagnostic dilemma and its laparoscopic management. JLAST 20(3):225–229
9.
go back to reference Salobir BG, Keber I, Vrabič L (2002) A randomized, placebo-controlled trial of the effects of continuous combined hormone replacement therapy on coagulation and fibrinolytic systems in healthy postmenopausal women. Fertil Steril 78(6):1178–1183PubMedCrossRef Salobir BG, Keber I, Vrabič L (2002) A randomized, placebo-controlled trial of the effects of continuous combined hormone replacement therapy on coagulation and fibrinolytic systems in healthy postmenopausal women. Fertil Steril 78(6):1178–1183PubMedCrossRef
10.
go back to reference Habiba M, Akkad A, Al-Azzawi F (1995) Effect of a new cyclical sequential postmenopausal HRT on lipoprotein, apoprotein and thrombophilia profile. Eur J Obstet Gynecol Reprod Biol 62(1):89–94PubMedCrossRef Habiba M, Akkad A, Al-Azzawi F (1995) Effect of a new cyclical sequential postmenopausal HRT on lipoprotein, apoprotein and thrombophilia profile. Eur J Obstet Gynecol Reprod Biol 62(1):89–94PubMedCrossRef
11.
go back to reference Pabinger I, Schneider B (1996) Thrombotic risk in hereditary antithrombin III, protein C, or protein S deficiency. A cooperative, retrospective study. Gesellschaft fur Thrombose- und Hamostaseforschung (GTH) Study Group on Natural Inhibitors. Arterioscler Thromb Vasc Biol 6(6):742–748CrossRef Pabinger I, Schneider B (1996) Thrombotic risk in hereditary antithrombin III, protein C, or protein S deficiency. A cooperative, retrospective study. Gesellschaft fur Thrombose- und Hamostaseforschung (GTH) Study Group on Natural Inhibitors. Arterioscler Thromb Vasc Biol 6(6):742–748CrossRef
Metadata
Title
Omental Gangrene and Porto-Mesenteric Thrombosis in a Patient of Protein C and Protein S Deficiency
Authors
Nirmal M. Patle
Om Tantia
Prakhar Chandra Das
Jayanta Mukherjee
Parmanand Prasad
Publication date
01-06-2013
Publisher
Springer India
Published in
Indian Journal of Surgery / Issue Special Issue 1/2013
Print ISSN: 0972-2068
Electronic ISSN: 0973-9793
DOI
https://doi.org/10.1007/s12262-012-0751-x

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