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01-07-2009 | Case Report

Severe hyperleukocytosis and multifocal intracranial haemorrhage: not always a fatal outcome

Authors: Antonio Ruggiero, G. Attinà, M. Piastra, P. Maurizi, S. Mastrangelo, D. Pietrini, R. Riccardi

Published in: International Journal of Hematology | Issue 1/2009

Abstract

Severe hyperleukocytosis caused by acute lymphoblastic leukaemia (ALL) is associated with an increased risk of early death due to the intracranial haemorrhage. We report on a boy who presented with ALL with an extremely high leukocyte count, who developed neurological deterioration due to multiple intracerebral haemorrhages. Adequate measures for managing this medical emergency include appropriate supportive measures and initiation of therapy to prevent symptoms of leukostasis. Aggressive measures as a decompressive craniectomy should be considered to improve the poor outcome observed in this subset of patients.

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Title: Severe hyperleukocytosis and multifocal intracranial haemorrhage: not always a fatal outcome
Authors: Antonio Ruggiero
G. Attinà
M. Piastra
P. Maurizi
S. Mastrangelo
D. Pietrini
R. Riccardi
Publication date: 01-07-2009
Publisher: Springer Japan
Published in: International Journal of Hematology / Issue 1/2009
Print ISSN: 0925-5710
Electronic ISSN: 1865-3774
DOI: https://doi.org/10.1007/s12185-009-0333-2

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