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Published in: Annals of Behavioral Medicine 1/2014

01-02-2014 | Original Article

Sexual Orientation and Gender Differences in Markers of Inflammation and Immune Functioning

Authors: Bethany G. Everett, PhD, Margaret Rosario, PhD, Katie A. McLaughlin, PhD, S. Bryn Austin, ScD

Published in: Annals of Behavioral Medicine | Issue 1/2014

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Abstract

Background

Sexual minorities have documented elevated risk factors that can lead to inflammation and poor immune functioning.

Purpose

This study aims to investigate disparities in C-reactive protein (CRP) and Epstein–Barr virus (EBV) by gender and sexual orientation.

Methods

We used the National Longitudinal Study of Adolescent Health to examine disparities in CRP (N = 11,462) and EBV (N = 11,812).

Results

Among heterosexuals, women had higher levels of CRP and EBV than men. However, sexual minority men had higher levels of CRP and EBV than heterosexual men and sexual minority women. Lesbians had lower levels of CRP than heterosexual women.

Conclusions

Gender differences in CRP and EBV found between men and women who identify as 100 % heterosexual were reversed among sexual minorities and not explained by known risk factors (e.g., victimization, alcohol and tobacco use, and body mass index). More nuanced approaches to addressing gender differences in sexual orientation health disparities that include measures of gender nonconformity and minority stress are needed.
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Metadata
Title
Sexual Orientation and Gender Differences in Markers of Inflammation and Immune Functioning
Authors
Bethany G. Everett, PhD
Margaret Rosario, PhD
Katie A. McLaughlin, PhD
S. Bryn Austin, ScD
Publication date
01-02-2014
Publisher
Springer US
Published in
Annals of Behavioral Medicine / Issue 1/2014
Print ISSN: 0883-6612
Electronic ISSN: 1532-4796
DOI
https://doi.org/10.1007/s12160-013-9567-6

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