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Annals of Behavioral Medicine
Published in: Annals of Behavioral Medicine 2/2013

01-10-2013 | Original Article

Physical Activity and Health Outcomes Among HIV-Infected Men Who Have Sex with Men: A Longitudinal Mediational Analysis

Authors: Aaron J. Blashill, Ph.D., Kenneth H. Mayer, M.D, Heidi Crane, M.D., Jessica F. Magidson, M.S., Chris Grasso, M.P.H., W. Christopher Mathews, M.D., M.S.P.H., Michael S. Saag, M.D., Steven A. Safren, Ph.D.

Published in: Annals of Behavioral Medicine | Issue 2/2013

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Abstract

Background

Low physical activity is associated with depression, which may, in turn, negatively impact antiretroviral therapy (ART) adherence among HIV-infected individuals; however, prior studies have not investigated the relationships between physical inactivity and ART non-adherence.

Purpose

The purpose of this study was to examine the association of physical inactivity, depression, ART non-adherence, and viral load in HIV-infected men who have sex with men.

Methods

The sample (N = 860) was from a large, multicenter cohort of HIV-infected patients engaged in clinical care.

Results

Across time, depression mediated the relationship between physical inactivity and ART non-adherence (γ = 0.075) and the relationship between physical inactivity and viral load (γ = 0.05). ART non-adherence mediated the relationship between depression and viral load (γ = 0.002) and the relationship between physical inactivity and viral load (γ = 0.009).

Conclusions

Low levels of physical activity predicted increased depression and poor ART adherence over time, which subsequently predicted higher viral load.
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Metadata
Title
Physical Activity and Health Outcomes Among HIV-Infected Men Who Have Sex with Men: A Longitudinal Mediational Analysis
Authors
Aaron J. Blashill, Ph.D.
Kenneth H. Mayer, M.D
Heidi Crane, M.D.
Jessica F. Magidson, M.S.
Chris Grasso, M.P.H.
W. Christopher Mathews, M.D., M.S.P.H.
Michael S. Saag, M.D.
Steven A. Safren, Ph.D.
Publication date
01-10-2013
Publisher
Springer US
Published in
Annals of Behavioral Medicine / Issue 2/2013
Print ISSN: 0883-6612
Electronic ISSN: 1532-4796
DOI
https://doi.org/10.1007/s12160-013-9489-3

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