Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on medication adherence

LIVE: Thursday 27th June 2024, 18:00-19:30 (CEST)
Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.
ADVANCED SEARCH
Log in
Top
Annals of Behavioral Medicine
Published in: Annals of Behavioral Medicine 3/2011

01-06-2011 | Original Article

Depression and Anxiety Predict Decline in Physical Health Functioning in Patients with Heart Failure

Authors: Biing-Jiun Shen, PhD, Stacy A. Eisenberg, MA, Uta Maeda, MA, Kristin A. Farrell, MS, Ernst R. Schwarz, MD, PhD, Frank J. Penedo, PhD, Eugene J. Bauerlein, MD, Stephen Mallon, MD

Published in: Annals of Behavioral Medicine | Issue 3/2011

Login to get access

Abstract

Background

Few studies have examined the prospective influences of depression and anxiety on physical health functioning in heart failure (HF) patients. Prior studies were also limited by employing psychological measures containing somatic items confounded with HF symptoms.

Purpose

This study examined whether depression, anxiety, social support, and their changes predicted the decline of physical functioning in HF patients over 6 months.

Methods

Participants were 238 HF patients among whom 164 provided follow-up data. The depression and anxiety measures did not contain somatic items.

Results

After controlling for baseline physical functioning and demographic and medical covariates, baseline depression and its increase, as well as baseline anxiety and its increase, independently predicted greater decline in physical functioning at 6 months. Social support and its change were not associated with either concurrent or follow-up physical functioning.

Conclusions

Depression, anxiety, and their changes independently predicted the decline of physical health functioning over 6 months.
Literature
1.
AHA: Heart disease and stroke statistics—2009 update: American Heart Association, 2009.
2.
Rutledge T, Reis VA, Linke SE, Greenberg BH, Mills PJ: Depression in heart failure a meta-analytic review of prevalence, intervention effects, and associations with clinical outcomes. J Am Coll Cardiol. 2006, 48:1527–1537.PubMedCrossRef
3.
Haworth JE, Moniz-Cook E, Clark AL, et al.: Prevalence and predictors of anxiety and depression in a sample of chronic heart failure patients with left ventricular systolic dysfunction. Eur J Heart Fail. 2005, 7:803–808.PubMedCrossRef
4.
Friedmann E, Thomas SA, Liu F, et al.: Relationship of depression, anxiety, and social isolation to chronic heart failure outpatient mortality. Am Heart J. 2006, 152:940 e941–e948.
5.
De Jong MJ, Moser DK, An K, Chung ML: Anxiety is not manifested by elevated heart rate and blood pressure in acutely ill cardiac patients. European Journal of Cardiovascular Nursing. 2004, 3:247–253.PubMedCrossRef
6.
Albert NM, Fonarow GC, Abraham WT, et al.: Depression and clinical outcomes in heart failure: An OPTIMIZE-HF analysis. Am J Med. 2009, 122:366–373.PubMedCrossRef
7.
Faller H, Stork S, Schowalter M, et al.: Depression and survival in chronic heart failure: Does gender play a role? Eur J Heart Fail. 2007, 9:1018–1023.PubMedCrossRef
8.
Frasure-Smith N, Lesperance F, Habra M, et al.: Elevated depression symptoms predict long-term cardiovascular mortality in patients with atrial fibrillation and heart failure. Circulation. 2009, 120:134–140, 133p following 140.
9.
Jiang W, Alexander J, Christopher E, et al.: Relationship of depression to increased risk of mortality and rehospitalization in patients with congestive heart failure. Arch Intern Med. 2001, 161:1849–1856.PubMedCrossRef
10.
Jiang W, Kuchibhatla M, Cuffe MS, et al.: Prognostic value of anxiety and depression in patients with chronic heart failure. Circulation. 2004, 110:3452–3456.PubMedCrossRef
11.
Junger J, Schellberg D, Muller-Tasch T, et al.: Depression increasingly predicts mortality in the course of congestive heart failure. Eur J Heart Fail. 2005, 7:261–267.PubMedCrossRef
12.
Sherwood A, Blumenthal JA, Trivedi R, et al.: Relationship of depression to death or hospitalization in patients with heart failure. Arch Intern Med. 2007, 167:367–373.PubMedCrossRef
13.
Tsuchihashi-Makaya M, Kato N, Chishaki A, Takeshita A, Tsutsui H: Anxiety and poor social support are independently associated with adverse outcomes in patients with mild heart failure. Circ J. 2009, 73:280–287.PubMedCrossRef
14.
Bekelman DB, Havranek EP, Becker DM, et al.: Symptoms, depression, and quality of life in patients with heart failure. J Card Fail. 2007, 13:643–648.PubMedCrossRef
15.
Faller H, Stork S, Schuler M, et al.: Depression and disease severity as predictors of health-related quality of life in patients with chronic heart failure—a structural equation modeling approach. J Card Fail. 2009, 15:286–292 e282.PubMedCrossRef
16.
Gottlieb SS, Khatta M, Friedmann E, et al.: The influence of age, gender, and race on the prevalence of depression in heart failure patients. J Am Coll Cardiol. 2004, 43:1542–1549.PubMedCrossRef
17.
Muller-Tasch T, Peters-Klimm F, Schellberg D, et al.: Depression is a major determinant of quality of life in patients with chronic systolic heart failure in general practice. J Card Fail. 2007, 13:818–824.PubMedCrossRef
18.
Vaccarino V, Kasl SV, Abramson J, Krumholz HM: Depressive symptoms and risk of functional decline and death in patients with heart failure. J Am Coll Cardiol. 2001, 38:199–205.PubMedCrossRef
19.
Clarke SP, Frasure-Smith N, Lesperance F, Bourassa AG: Psychosocial factors as predictors of functional status at 1 year in patients with left ventricular dysfunction. Research in Nursing and Health. 2000, 23:290–300.PubMedCrossRef
20.
Chung ML, Moser DK, Lennie TA, Rayens MK: The effects of depressive symptoms and anxiety on quality of life in patients with heart failure and their spouses: Testing dyadic dynamics using Actor-Partner Interdependence Model. J Psychosom Res. 2009, 67:29–35.PubMedCrossRef
21.
Muller-Tasch T, Frankenstein L, Holzapfel N, et al.: Panic disorder in patients with chronic heart failure. J Psychosom Res. 2008, 64:299–303.PubMedCrossRef
22.
Murberg TA: Long-term effect of social relationships on mortality in patients with congestive heart failure. Int J Psychiatry Med. 2004, 34:207–217.PubMedCrossRef
23.
Bennett SJ, Perkins SM, Lane KA, et al.: Social support and health-related quality of life in chronic heart failure patients. Qual Life Res. 2001, 10:671–682.PubMedCrossRef
24.
Rector TS, Kubo SH, Cohn JN: Patients' self-assessment of their congestive heart failure. Part 2: Content, reliability and validity of a new measure, the Minnesota Living with Heart Failure Questionnaire Heart Failure. 1987:198–209.
25.
Rector TS, Cohn JN: Assessment of patient outcome with the Minnesota Living with Heart Failure questionnaire: Reliability and validity during a randomized, double-blind, placebo-controlled trial of pimobendan. Pimobendan Multicenter Research Group. Am Heart J. 1992, 124:1017–1025.PubMedCrossRef
26.
Garin O, Ferrer M, Pont A, et al.: Disease-specific health-related quality of life questionnaires for heart failure: A systematic review with meta-analyses. Qual Life Res. 2009, 18:71–85.PubMedCrossRef
27.
Radloff LS: The CES-D scale: A self report depression scale for research in general populations. Applied Psychological Measurement. 1977, 1:385–401.CrossRef
28.
Radloff LS, Locke BZ: The Community Mental Health Assessment Survey and the CES-D Scale. In M. M. Weissman, J. K. Myers and C. E. Ross (eds), Community Surveys of Psychiatric Disorders. New Brunswick, NJ: Rutgers University Press, 1986, 177–189.
29.
Callahan CM, Wolinsky FD. The effect of gender and race on the measurement properties of the CES-D in older adults. Med Care. Apr 1994, 32: 341–356.PubMedCrossRef
30.
Knight RG, Williams S, McGee R, Olaman S. Psychometric properties of the Centre for Epidemiologic Studies Depression Scale (CES-D) in a sample of women in middle life. Behav Res Ther. Apr 1997, 35: 373–380.PubMedCrossRef
31.
Zigmond AS, Snaith RP: The hospital anxiety and depression scale. Acta Psychiatr Scand. 1983, 67:361–370.PubMedCrossRef
32.
33.
Riedinger MS, Dracup KA, Brecht ML et al.: Quality of life in patients with heart failure: Do gender differences exist? Heart Lung. 2001, 30:105–116.PubMedCrossRef
34.
Rumsfeld JS, Havranek E, Masoudi FA, et al.: Depressive symptoms are the strongest predictors of short-term declines in health status in patients with heart failure. J Am Coll Cardiol. 2003, 42: 1811–1817.PubMedCrossRef
35.
Cress ME, Schechtman KB, Mulrow CD, et al.: Relationship between physical performance and self-perceived physical function. J Am Geriatr Soc. 1995, 43:93–101.PubMed
36.
Watson D & Pennebaker JW: Health complaints, stress, and distress: Exploring the central role of negative affectivity. Psychol Rev. 1989, 96:235–254. CrossRef
37.
Juenger J, Schellberg D, Kraemer S, et al.: Health related quality of life in patients with congestive heart failure: Comparison with other chronic diseases and relation to functional variables. Heart. 2002, 87: 235–241.PubMedCrossRef
38.
Rodriguez-Artalejo F, Guallar-Castillon P, Pascual CR, et al.: Health-related quality of life as a predictor of hospital readmission and dealth among patients with heart failure. Arch Intern Med. 2002, 165: 1274–1279.CrossRef
39.
Rozanski A, Blumenthal JA, Davidson KW, Saab PG, Kubzansky L: The epidemiology, pathophysiology, and management of psychosocial risk factors in cardiac practice: The emerging field of behavioral cardiology. J Am Coll Cardiol. 2005, 45:637–651.PubMedCrossRef
40.
Kubzansky LD, Kawachi I, Weiss ST, Sparrow D: Anxiety and coronary heart disease: A synthesis of epidemiological, psychological, and experimental evidence. Ann Behav Med. 1998, 20:47–58.PubMedCrossRef
41.
DiMatteo MR, Lepper HS, Croghan TW: Depression is a risk factor for noncompliance with medical treatment: Meta-analysis of the effects of anxiety and depression on patient adherence. Arch Intern Med. 2000, 160:2101–2107.PubMedCrossRef
42.
Ziegelstein RC, Fauerbach JA, Stevens SS, et al.: Patients with depression are less likely to follow recommendations to reduce cardiac risk during recovery from a myocardial infarction. Arch Intern Med. 2000, 160:1818–1823.PubMedCrossRef
43.
House JS, Umberson D, Landis KR: Structures and processes of social support. Annual Review of Sociology. 1988, 14:293–318.CrossRef
Metadata
Title
Depression and Anxiety Predict Decline in Physical Health Functioning in Patients with Heart Failure
Authors
Biing-Jiun Shen, PhD
Stacy A. Eisenberg, MA
Uta Maeda, MA
Kristin A. Farrell, MS
Ernst R. Schwarz, MD, PhD
Frank J. Penedo, PhD
Eugene J. Bauerlein, MD
Stephen Mallon, MD
Publication date
01-06-2011
Publisher
Springer-Verlag
Published in
Annals of Behavioral Medicine / Issue 3/2011
Print ISSN: 0883-6612
Electronic ISSN: 1532-4796
DOI
https://doi.org/10.1007/s12160-010-9251-z

Other articles of this Issue 3/2011

Annals of Behavioral Medicine 3/2011 Go to the issue

Original Article

Further Evaluation of the Motivational Model of Pain Self-Management: Coping with Chronic Pain in Multiple Sclerosis

Original Article

Diabetes and Co-morbid Depression Among Racially Diverse, Low-Income Adults

Original Article

Examining the Relationships Between Family Meal Practices, Family Stressors, and the Weight of Youth in the Family

Original Article

Is the Neighbourhood Environment Associated with Sedentary Behaviour Outside of School Hours Among Children?

Original Article

Predictors of Adherence to Secondary Preventive Medication in Stroke Patients

Original Article

A Randomized Controlled Trial of a Tailored Interactive Computer-Delivered Intervention to Promote Colorectal Cancer Screening: Sometimes More is Just the Same