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Published in: Annals of Nuclear Medicine 10/2009

01-12-2009 | Case Report

Intense accumulation of 18F-FDG, not enhancement on MRI, helps to guide the surgical biopsy accurately in soft tissue tumors

Authors: Jong Hoon Park, Eun Kyung Park, Chang Ho Kang, Chul Hwan Kim, Jae Gol Choe, Won Noh

Published in: Annals of Nuclear Medicine | Issue 10/2009

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Abstract

Soft tissue sarcomas are a highly heterogeneous group of malignancies that arise from mesenchymal tissues. Grading of soft tissue sarcomas is an important prerequisite for the choice of therapy and estimation of prognosis. However, incisional biopsy of huge soft tissue sarcoma lesions frequently fails to provide an accurate diagnosis when there is a benign component, cystic changes and/or necrosis. MRI is helpful in evaluating the extent of the sarcoma lesion, vascularization, invasiveness and integrity of surrounding tissue, but definitive differentiation of benignity and malignancy is not possible with it. In this study, positron emission tomography using [18F]-2-fluoro-2-deoxy-d-glucose successfully guided surgeons to identify the most hypermetabolic and, therefore, the most suitable biopsy sites of huge soft tissue sarcoma.
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Metadata
Title
Intense accumulation of 18F-FDG, not enhancement on MRI, helps to guide the surgical biopsy accurately in soft tissue tumors
Authors
Jong Hoon Park
Eun Kyung Park
Chang Ho Kang
Chul Hwan Kim
Jae Gol Choe
Won Noh
Publication date
01-12-2009
Publisher
Springer Japan
Published in
Annals of Nuclear Medicine / Issue 10/2009
Print ISSN: 0914-7187
Electronic ISSN: 1864-6433
DOI
https://doi.org/10.1007/s12149-009-0313-x

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