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Head and Neck Pathology
Published in: Head and Neck Pathology 3/2019

01-09-2019 | Case Report

Oral Mycosis Fungoides: A Report of Three Cases and Review of the Literature

Authors: Molly S. Rosebush, Carl M. Allen, Brent T. Accurso, Robert A. Baiocchi, Kitrina G. Cordell

Published in: Head and Neck Pathology | Issue 3/2019

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Abstract

Mycosis fungoides (MF) and Sézary syndrome are clonal T-cell proliferations that exhibit skin homing and represent the majority of cutaneous T-cell lymphomas. Early MF is a diagnostic challenge as both the clinical and microscopic features often mimic benign inflammatory conditions. Oral MF is very rare and has been associated in the past with advanced disease and a poor prognosis. Skin lesions are present for an average of > 6 years before oral involvement occurs. The clinical appearance is highly variable with tongue, palate and gingiva most often affected. We report 3 additional cases of oral MF, including one in which oral lesions are the initial disease presentation. Survival in patients presenting with oral MF is improving and can be attributed to advances in therapy.
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Metadata
Title
Oral Mycosis Fungoides: A Report of Three Cases and Review of the Literature
Authors
Molly S. Rosebush
Carl M. Allen
Brent T. Accurso
Robert A. Baiocchi
Kitrina G. Cordell
Publication date
01-09-2019
Publisher
Springer US
Published in
Head and Neck Pathology / Issue 3/2019
Electronic ISSN: 1936-0568
DOI
https://doi.org/10.1007/s12105-018-0923-5

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