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Head and Neck Pathology
Published in: Head and Neck Pathology 1/2016

01-03-2016 | Special Issue: Sinonasal Tract Pathology. Guest Editors: Justin Bishop, MD and Alessandro Franchi, MD

Sinonasal Squamous Cell Carcinoma: A Review with Emphasis on Emerging Histologic Subtypes and the Role of Human Papillomavirus

Author: James S. Lewis Jr.

Published in: Head and Neck Pathology | Issue 1/2016

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Abstract

The sinonasal tract is one of the least frequent sites for squamous cell carcinoma in the head and neck. However, it is still a complex tumor type for pathologists because there are numerous histologic variants with unusual morphologic features, several non-squamous carcinomas in the differential diagnosis that can have similar morphology and even squamous differentiation, and because of the increasing recognition of human papillomavirus (HPV) in a subset of the tumors. In addition, the unique and complex anatomy of the sinonasal tract can make proper staging and management of patients’ tumors quite challenging. This article reviews sinonasal tract squamous cell carcinoma in depth and provides the latest data on Schneiderian papillomas and HPV in their pathogenesis.
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Metadata
Title
Sinonasal Squamous Cell Carcinoma: A Review with Emphasis on Emerging Histologic Subtypes and the Role of Human Papillomavirus
Author
James S. Lewis Jr.
Publication date
01-03-2016
Publisher
Springer US
Published in
Head and Neck Pathology / Issue 1/2016
Electronic ISSN: 1936-0568
DOI
https://doi.org/10.1007/s12105-016-0692-y

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