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Head and Neck Pathology
Published in: Head and Neck Pathology 2/2012

01-06-2012 | Sine qua non Radiology-Pathology

Sclerosing Polycystic Adenosis

Authors: Colin A. Eliot, Alice B. Smith, Robert D. Foss

Published in: Head and Neck Pathology | Issue 2/2012

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Abstract

A 25-year-old female presented with a well-defined, painless mass of 1 year’s duration in the right parotid gland. MR imaging revealed a relatively well-circumscribed lesion involving the deep and superficial lobes of the right parotid gland. Histologic examination of the resection resulted in a diagnosis of sclerosing polycystic adenosis, a rare benign salivary gland entity of presumed non-neoplastic origin. The clinical, radiographic, and morphologic features of sclerosing polycystic adenosis are discussed.
Literature
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Smith BC, Ellis GL, Slater LJ, et al. Sclerosing polycystic adenosis of major salivary glands: a clinicopathologic analysis of nine cases. Am J Surg Pathol. 1996;20:161–70.PubMedCrossRef
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Gnepp DR, Wang LJ, Brandwein-Gensler M, et al. Sclerosing polycystic adenosis of the salivary gland. a report of 16 cases. Am J Surg Pathol. 2006;30:154–64.PubMedCrossRef
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Swelam WM. The pathogenic role of Epstein-Barr virus (EBV) in sclerosing polycystic adenosis. Pathol Res Pract. 2010;206:565–71.PubMedCrossRef
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Skálová A, Gnepp DR, Simpson RH, et al. Clonal nature of sclerosing polycystic adenosis of salivary glands demonstrated by using the polymorphism of the human androgen receptor (HUMARA) locus as a marker. Am J Surg Pathol. 2006;30:939–44.PubMedCrossRef
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Bharadwaj G, Nawroz I, O’Regan B. Sclerosing polycystic adenosis of the parotid gland. Br J Oral Maxillofac Surg. 2007;45:74–6.PubMedCrossRef
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Etit D, Pilch BZ, Osgood R, et al. Fine-needle aspiration biopsy findings in sclerosing polycystic adenosis of the parotid gland. Diagn Cytopathol. 2007;37:444–7.CrossRef
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Fulciniti F, Losito NS, Ionna F, et al. Sclerosing polycystic adenosis of the partotid gland: a report of one case diagnosed by fine-needle cytology with in situ malignant transformation. Diagn Cytopathol. 2010;38:368–73.PubMed
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Skálová A, Michal M, Simpson RH, et al. Sclerosing polycystic adenosis of parotid gland with dysplasia and ductal carcinoma in situ. Virchows Arch. 2002;440:29–35.PubMedCrossRef
Metadata
Title
Sclerosing Polycystic Adenosis
Authors
Colin A. Eliot
Alice B. Smith
Robert D. Foss
Publication date
01-06-2012
Publisher
Springer US
Published in
Head and Neck Pathology / Issue 2/2012
Electronic ISSN: 1936-0568
DOI
https://doi.org/10.1007/s12105-011-0317-4

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