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01-09-2011 | Case Report

Solitary Fibrous Tumor with Entrapment of Minor Salivary Gland Tissue: An Unusual Presentation That Requires Exclusion of Pleomorphic Adenoma

Authors: Jose Luis Tapia, Samuel Goodloe III, Joseph E. Margarone III, Michael R. Markiewicz, Alfredo Aguirre

Published in: Head and Neck Pathology | Issue 3/2011

Abstract

We report two unusual cases of solitary fibrous tumor (SFT) of minor salivary glands that microscopically mimicked pleomorphic adenoma. One of these lesions presented in the retromolar region and the other in the buccal mucosa. The microscopic features of these two tumors and their intimate relationship with regional mucous minor salivary glands posed a diagnostic challenge. Awareness of the morphological diversity of SFT coupled to a judicious use of appropriate immunohistochemical probes should prove valuable to accurately segregate SFT from pleomorphic adenoma.

Klemperer P, Rabin CB. Primary neoplasm of the pleura: a report of 5 cases. Arch Pathol (Chic). 1931;11:28.

Lo Muzio L, Mascolo M, Capodiferro S, et al. Solitary fibrous tumor of the oral cavity: the need for an extensive sampling for a correct diagnosis. J Oral Pathol Med. 2007;36:538–42.PubMedCrossRef

Alawi F, Stratton D, Freedman PD. Solitary fibrous tumor of the oral soft tissues: a clinicopathologic and immunohistochemical study of 16 cases. Am J Surg Pathol. 2001;25:900–10.PubMedCrossRef

Cox DP, Daniels T, Jordan RC. Solitary fibrous tumor of the head and neck. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010;110:79–84.PubMedCrossRef

Chan JK. Solitary fibrous tumour–everywhere, and a diagnosis in vogue. Histopathology. 1997;31:568–76.PubMedCrossRef

Magdeleinat P, Alifano M, Petino A, et al. Solitary fibrous tumors of the pleura: clinical characteristics, surgical treatment and outcome. Eur J Cardiothorac Surg. 2002;21:1087–93.PubMedCrossRef

Vallat-Decouvelaere AV, Dry SM, Fletcher CD. Atypical and malignant solitary fibrous tumors in extrathoracic locations: evidence of their comparability to intra-thoracic tumors. Am J Surg Pathol. 1998;22:1501–11.PubMedCrossRef

O’Regan EM, Vanguri V, Allen CM. Solitary fibrous tumor of the oral cavity: clinicopathologic and immunohistochemical study of 21 cases. Head Neck Pathol. 2009;3:106–15.PubMedCrossRef

Stout AP, Murray MR. Localized pleura mesothelioma: investigation of its characteristics and histogenesis by method of tissue culture. Arch Pathol. 1942;34:951–64.

10.

el-Naggar AK, Ro JY, Ayala AG, et al. Localized fibrous tumor of the serosal cavities. Immunohistochemical, electron-microscopic, and flow-cytometric DNA study. Am J Clin Pathol. 1989;92:561–5.PubMed

11.

Fletcher CD. The evolving classification of soft tissue tumours: an update based on the new WHO classification. Histopathology. 2006;48:3–12.PubMedCrossRef

12.

Kintarak S, Natiella J, Aguirre A, et al. Giant cell angiofibroma of the buccal mucosa. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1999;88(6):707–13.PubMedCrossRef

13.

Park MS, Araujo DM. New insights into the hemangiopericytoma/solitary fibrous tumor spectrum of tumors. Curr Opin Oncol. 2009;21:327–31.PubMedCrossRef

14.

Gengler C, Guillou L. Solitary fibrous tumour and haemangiopericytoma: evolution of a concept. Histopathology. 2006;48:63–74.PubMedCrossRef

15.

Weiss SW, Goldblum JR, editors. Enzinger & Weiss’s soft tissue tumors. Philadelphia: Mosby Elsevier; 2008. p. 1134.

16.

Swelam W, Ida-Yonemochi H, Maruyama S, et al. Solitary fibrous tumor of the lower lip involving minor salivary gland components: report of a case and review of the literature of salivary gland cases. Oral Oncol Extra. 2004;40:107–12.CrossRef

17.

Speight PM. Update on diagnostic difficulties in lesions of the minor salivary glands. Head Neck Pathol. 2007;1:55–60.PubMedCrossRef

18.

Speight PM, Barrett AW. Salivary gland tumours. Oral Dis. 2002;8:229–40.PubMedCrossRef

19.

Haskell HD, Butt KM, Woo SB. Pleomorphic adenoma with extensive lipometaplasia: report of three cases. Am J Surg Pathol. 2005;29:1389–93.PubMedCrossRef

20.

Ihrler S, Schwarz S, Zengel P, et al. Pleomorphic adenoma: pitfalls and clinicopathological forms of progression. Pathologe. 2009;30:446–56.PubMedCrossRef

21.

Soares AB, de Araujo VC, Juliano PB, et al. Angiogenic and lymphangiogenic microvessel density in recurrent pleomorphic adenoma. J Oral Pathol Med. 2009;38:623–9.PubMedCrossRef

22.

Dal Cin P, Sciot R, Fletcher CD, et al. Trisomy 21 in solitary fibrous tumor. Cancer Genet Cytogenet. 1996;86:58–60.PubMedCrossRef

23.

Miettinen MM, el-Rifai W, Sarlomo-Rikala M, et al. Tumor size-related DNA copy number changes occur in solitary fibrous tumors but not in hemangiopericytomas. Mod Pathol. 1997;10:1194–200.PubMed

24.

Eveson JW, Kusafuka, Stenman G, Nagao T. Pleomorphic adenoma. In: Barnes L, Eveson JW, Reichart P, Sidransky D, editors. Pathology and genetics of head and neck tumours. Kleihues P, Sobin LH, series editors. World Helath Organization classification of tumours. Lyon, France: IARC Press; 2005. p. 256–7.

Title: Solitary Fibrous Tumor with Entrapment of Minor Salivary Gland Tissue: An Unusual Presentation That Requires Exclusion of Pleomorphic Adenoma
Authors: Jose Luis Tapia
Samuel Goodloe III
Joseph E. Margarone III
Michael R. Markiewicz
Alfredo Aguirre
Publication date: 01-09-2011
Publisher: Springer US
Published in: Head and Neck Pathology / Issue 3/2011
Electronic ISSN: 1936-0568
DOI: https://doi.org/10.1007/s12105-011-0254-2

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Solitary Fibrous Tumor with Entrapment of Minor Salivary Gland Tissue: An Unusual Presentation That Requires Exclusion of Pleomorphic Adenoma

Abstract

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Abstract

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