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01-12-2008 | Case Report

Low-Grade Papillary Adenocarcinoma of the Palate: The Significance of Distinguishing it from Polymorphous Low-Grade Adenocarcinoma

Authors: Jacob B. Hunter, Richard V. Smith, Margaret Brandwein-Gensler

Published in: Head and Neck Pathology | Issue 4/2008

Abstract

Low-grade papillary adenocarcinoma (LGPA) represents a relatively rare histological variant of polymorphous low-grade adenocarcinoma (PLGA). There has been a debate as to whether LGPA is associated with greater aggressive potential compared to PLGA; this is further obfuscated by the fact that diagnostic criteria for LGPA have not been well-defined. We believe that this is the first report of a patient with LGPA who developed metastases to the femur and scalp. We review the published evidence for classifying LGPA as distinct from PLGA. The weight of published data does support the idea that LGPA is oncologically distinct from LGPA. However, as uniform diagnostic criteria are lacking, we suggest a cut-off value of 10% or greater papillary formation as being necessary to separate LGPA from PLGA.

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Title: Low-Grade Papillary Adenocarcinoma of the Palate: The Significance of Distinguishing it from Polymorphous Low-Grade Adenocarcinoma
Authors: Jacob B. Hunter
Richard V. Smith
Margaret Brandwein-Gensler
Publication date: 01-12-2008
Publisher: Humana Press Inc
Published in: Head and Neck Pathology / Issue 4/2008
Electronic ISSN: 1936-0568
DOI: https://doi.org/10.1007/s12105-008-0082-1

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Low-Grade Papillary Adenocarcinoma of the Palate: The Significance of Distinguishing it from Polymorphous Low-Grade Adenocarcinoma

Abstract

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Abstract

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