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Indian Journal of Pediatrics

14-08-2023 | Original Article

Functional Duration of Peripheral Intravenous Cannula in Neonates with or without Splint: A Randomized Controlled Trial

Authors: Nadella Lakshmi Thushara, Poonam Singh, Mayank Priyadarshi, Suman Chaurasia, Nowneet Kumar Bhat, Sriparna Basu

Published in: Indian Journal of Pediatrics

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Abstract

Objectives

To determine the effect of splint on the functional duration of peripheral intravenous cannula (PIVC) in neonates.

Methods

The trial was prospectively registered with the Clinical Trial Registry of India (CTRI/2021/09/036337). One-hundred-fifty cannulations in 71 neonates were randomized to splint (n = 75) and no-splint (n = 75) groups, respectively. The median (interquartile range, IQR) functional duration of PIVC was calculated from the time of PIVC insertion till removal due to the development of signs of PIVC failure or treatment completion. Kaplan–Meier survival analysis was used to compute the time to complication of PIVC. Complications related to PIVC were noted and multivariate Cox-proportion hazard analysis was done to find the predictors associated with PIVC failure.

Results

Median (IQR) functional duration of PIVC in the splint and the no-splint group was 28 (23–48) and 30 (25–48) h, respectively (p = 0.477). PIVC duration was higher in the splint group in term neonates and the no-splint group in preterm neonates; however, the differences were not statistically significant. No difference was observed in continuous vs. intermittent infusion subgroups. Time to complication development was also comparable between the groups.

Conclusions

Splint application did not affect functional PIVC duration and its related complications in neonates.
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Literature
1.
Legemaat M, Carr PJ, van Rens RM, van Dijk M, Poslawsky IE, van den Hoogen A. Peripheral intravenous cannulation: Complication rates in the neonatal population: A multicenter observational study. J Vasc Access. 2016;17:360–5.CrossRefPubMed
2.
Unbeck M, Förberg U, Ygge BM, Ehrenberg A, Petzold M, Johansson E. Peripheral venous catheter related complications are common among paediatric and neonatal patients. Acta Paediatr. 2015;104:566–74.CrossRefPubMed
3.
Atay S, Sen S, Cukurlu D. Incidence of infiltration/extravasation in newborns using peripheral venous catheter and affecting factors. Rev Esc Enferm USP. 2018;52:e03360.CrossRefPubMed
4.
van Rens MFPT, Hugill K, Mahmah MA, et al. Evaluation of unmodifiable and potentially modifiable factors affecting peripheral intravenous device-related complications in neonates: A retrospective observational study. BMJ Open. 2021;11:e047788.CrossRefPubMedPubMedCentral
5.
Chin LY, Walsh TA, Van Haltren K, Hayden L, Davies-Tuck M, Malhotra A. Elective replacement of intravenous cannula in neonates- A randomised trial. Eur J Pediatr. 2018;177:1719–26.CrossRefPubMed
6.
Gupta P, Rai R, Basu S, Faridi MM. Life span of peripheral intravenous cannula in a neonatal intensive care unit of a developing country. J Pediatr Nurs. 2003;18:287–92.
7.
Tandale SR, Dave N, Garasia M, Patil S, Parelkar S. A study of morbidity and cost of peripheral venous cannulation in neonates admitted to paediatric surgical intensive care unit. J Clin Diagn Res. 2017;11:UC08–10.
8.
Steere L, Ficara C, Davis M, Moureau NL. Reaching one peripheral intravenous catheter (PIVC) per patient visit with lean multimodal strategy: The PIV5Rights™ bundle. J AssocVasc Access. 2019;24:31–43.CrossRef
9.
Johnston CC, Stevens BJ. Experience in a neonatal intensive care unit affects pain response. Pediatrics. 1996;98:925–30.CrossRefPubMed
10.
Tripathi S, Kaushik V, Singh V. Peripheral IVs: Factors affecting complications and patency– A randomized controlled trial. J InfusNurs. 2008;31:182–8.
11.
Dalal SS, Chawla D, Singh J, Agarwal RK, Deorari AK, Paul VK. Limb splinting for intravenous cannulae in neonates: Arandomised controlled trial. Arch Dis Child Fetal Neonatal Ed. 2009;94:F394–6.CrossRefPubMed
12.
Raghavan M, BK P. Effect of joint immobilization on the Functional Duration of intravenous cannula: A randomised controlled trial. Int J Contemp Pediatr. 2015;2:411–4.
13.
Tewari N, Castellino S, Saste SS, et al. Effect of splinting versus not splinting limb joints on functional longevity of peripheral intravenous cannulae: A randomized controlled trial. Perinatology. 2021;21:151–7.
14.
Serane VT, Rajasekaran R, Vijayadevagaran V, Kothendaraman B. Peripheral intravenous cannulae in neonates: To splint or not? J Vasc Access. 2022;23:398–402.CrossRef
15.
16.
17.
Infusion Nurses Society. Infusion nursing standards of practice. J Infus Nurs. 2006;29:S1-92.
18.
Groll D, Davies B, Mac Donald J, Nelson S, Virani T. Evaluation of the psychometric properties of the phlebitis and infiltration scales for the assessment of complications of peripheral vascular access devices. J Infus Nurs. 2010;33:385–90.
19.
Indarwati F, Mathew S, Munday J, Keogh S. Incidence of peripheral intravenous catheter failure and complications in paediatric patients: Systematic review and meta analysis. Int J Nurs Stud. 2020;102:103488.CrossRefPubMed
20.
Beall V, Hall B, Mulholland JT, Gephart SM. Neonatal extravasation: An overview and algorithm for evidence-based treatment. Newborn Infant Nurs Rev. 2013;13:189–95.CrossRef
Metadata
Title
Functional Duration of Peripheral Intravenous Cannula in Neonates with or without Splint: A Randomized Controlled Trial
Authors
Nadella Lakshmi Thushara
Poonam Singh
Mayank Priyadarshi
Suman Chaurasia
Nowneet Kumar Bhat
Sriparna Basu
Publication date
14-08-2023
Publisher
Springer India
Published in
Indian Journal of Pediatrics
Print ISSN: 0019-5456
Electronic ISSN: 0973-7693
DOI
https://doi.org/10.1007/s12098-023-04756-w