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Published in: Indian Journal of Pediatrics 8/2014

01-08-2014 | Original Article

Body Temperature Changes of Newborns Under Fluorescent Versus LED Phototherapy

Authors: Ozge Aydemir, Emel Soysaldı, Yusuf Kale, Sumru Kavurt, Ahmet Yagmur Bas, Nihal Demirel

Published in: Indian Journal of Pediatrics | Issue 8/2014

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Abstract

Objective

To determine changes in body temperature (BT) of hyperbilirubinemic newborns under conventional phototherapy with fluorescent lamps and light emitting diodes (LED) at different irradiances.

Methods

Otherwise healthy newborn infants >34 wk gestational age (GA) hospitalized for indirect hyperbilirubinemia, requiring phototherapy in the first 10 d of life were enroled. Infants who received conventional phototherapy with fluorescent lamps (10–15 μW/cm2/nm irradiance) were defined as group 1, LED phototherapy of 26–60 μW/cm2/nm irradiance as group 2, and LED phototherapy of 60–120 μW/cm2/nm irradiance as group 3. Primary outcome measure was mean BT which was defined as arithmetical mean of axillary BT measured at 2 h intervals during the first day of phototherapy.

Results

Thirty patients were enroled in each group. Mean birth weight and GA of the total cohort was 2800 ± 530 g and 36.6 ± 2 wk, respectively. Baseline demographic variables and serum total bilirubin levels were similar among groups. Mean BT was 36.7 ± 0.1 °C in group 1, 36.6 ± 0.2 °C in group 2, 37.7 ± 0.2 °C in group 3. Mean BT was higher in group 3 compared to group 1 (p < 0.001) and group 2 (p < 0.001). Group 1 and group 2 had similar mean BT measurements (p = 0.09). During phototherapy all the patients in group 3 had at least one BT measurement ≥37.5 °C and 77 % had BT ≥38 °C. Only one patient in group 2 had BT ≥ 37.5 °C which was also ≥38 °C. During phototherapy all BT measurements were <37.5 °C in group 1.

Conclusions

LED phototherapy of ≥60 μW/cm2/nm intensity significantly increases BT in hyperbilirubinemic newborns.
Literature
1.
2.
go back to reference Shapiro SM. Definition of the clinical spectrum of kernicterus and bilirubin-induced neurologic dysfunction (BIND). J Perinatol. 2005;25:54–9.PubMedCrossRef Shapiro SM. Definition of the clinical spectrum of kernicterus and bilirubin-induced neurologic dysfunction (BIND). J Perinatol. 2005;25:54–9.PubMedCrossRef
3.
go back to reference American Academy of Pediatrics Subcommittee on Hyperbilirubinemia. Management of hyperbilirubinemia in the newborn infant 35 or more weeks of gestation. Pediatrics. 2004;114:297. American Academy of Pediatrics Subcommittee on Hyperbilirubinemia. Management of hyperbilirubinemia in the newborn infant 35 or more weeks of gestation. Pediatrics. 2004;114:297.
4.
go back to reference Verman HJ, Wong RJ, Stevenson DK. Phototherapy: Current methods and future directions. Semin Perinatol. 2004;28:326.CrossRef Verman HJ, Wong RJ, Stevenson DK. Phototherapy: Current methods and future directions. Semin Perinatol. 2004;28:326.CrossRef
5.
go back to reference Tan KL. The pattern of bilirubin response to phototherapy for neonatal hyperbilirubinaemia. Pediatr Res. 1982;16:670–4.PubMedCrossRef Tan KL. The pattern of bilirubin response to phototherapy for neonatal hyperbilirubinaemia. Pediatr Res. 1982;16:670–4.PubMedCrossRef
6.
go back to reference Maisels MJ. Phototherapy–traditional and nontraditional. J Perinatol. 2001;21:93–7.CrossRef Maisels MJ. Phototherapy–traditional and nontraditional. J Perinatol. 2001;21:93–7.CrossRef
7.
go back to reference Seidman DS, Moise J, Ergaz Z, Laor A, Vreman HJ, Stevenson DK, et al. A new blue light-emitting phototherapy device: A prospective randomized controlled study. J Pediatr. 2000;136:771–4.PubMed Seidman DS, Moise J, Ergaz Z, Laor A, Vreman HJ, Stevenson DK, et al. A new blue light-emitting phototherapy device: A prospective randomized controlled study. J Pediatr. 2000;136:771–4.PubMed
8.
go back to reference Kumar P, Murki S, Malik GK, Chawla D, Deorari AK, Karthi N, et al. Light emitting diodes versus compact fluorescent tubes for phototherapy in neonatal jaundice: A multi center randomized controlled trial. Indian Pediatr. 2010;47:131–7.PubMedCrossRef Kumar P, Murki S, Malik GK, Chawla D, Deorari AK, Karthi N, et al. Light emitting diodes versus compact fluorescent tubes for phototherapy in neonatal jaundice: A multi center randomized controlled trial. Indian Pediatr. 2010;47:131–7.PubMedCrossRef
9.
go back to reference Kumar P, Chawla D, Deorari A. Light-emitting diode phototherapy for unconjugated hyperbilirubinaemia in neonates. Cochrane Database Syst Rev. 2011;7:CD007969. Kumar P, Chawla D, Deorari A. Light-emitting diode phototherapy for unconjugated hyperbilirubinaemia in neonates. Cochrane Database Syst Rev. 2011;7:CD007969.
10.
go back to reference Haque KN. Definitions of bloodstream infection in the newborn. Pediatr Crit Care Med. 2005;6:S45–9.PubMedCrossRef Haque KN. Definitions of bloodstream infection in the newborn. Pediatr Crit Care Med. 2005;6:S45–9.PubMedCrossRef
11.
go back to reference Kreith F, Manglik RM, Bohn MS. Principals of Heat Transfer. 7th ed. Stamford: Global Engineering; 2011. Kreith F, Manglik RM, Bohn MS. Principals of Heat Transfer. 7th ed. Stamford: Global Engineering; 2011.
12.
go back to reference Netea MG, Kullberg BJ, Van der Meer JW. Circulating cytokines as mediators of fever. Clin Infect Dis. 2000;31:S178–84.PubMedCrossRef Netea MG, Kullberg BJ, Van der Meer JW. Circulating cytokines as mediators of fever. Clin Infect Dis. 2000;31:S178–84.PubMedCrossRef
13.
go back to reference Sirota L, Straussberg R, Gurary N, Aloni D, Bessler H. Phototherapy for neonatal hyperbilirubinemia affects cytokine production by peripheral blood mononuclear cells. Eur J Pediatr. 1999;158:910–3.PubMedCrossRef Sirota L, Straussberg R, Gurary N, Aloni D, Bessler H. Phototherapy for neonatal hyperbilirubinemia affects cytokine production by peripheral blood mononuclear cells. Eur J Pediatr. 1999;158:910–3.PubMedCrossRef
14.
go back to reference Kurt A, Aygun AD, Kurt AN, Godekmerdan A, Akarsu S, Yilmaz E. Use of phototherapy for neonatal hyperbilirubinemia affects cytokine production and lymphocyte subsets. Neonatology. 2009;95:262–6.PubMedCrossRef Kurt A, Aygun AD, Kurt AN, Godekmerdan A, Akarsu S, Yilmaz E. Use of phototherapy for neonatal hyperbilirubinemia affects cytokine production and lymphocyte subsets. Neonatology. 2009;95:262–6.PubMedCrossRef
15.
go back to reference Vandborg PK, Hansen BM, Greisen G, Ebbesen F. Dose–response relationship of phototherapy for hyperbilirubinemia. Pediatrics. 2012;130:e 352–7. Vandborg PK, Hansen BM, Greisen G, Ebbesen F. Dose–response relationship of phototherapy for hyperbilirubinemia. Pediatrics. 2012;130:e 352–7.
Metadata
Title
Body Temperature Changes of Newborns Under Fluorescent Versus LED Phototherapy
Authors
Ozge Aydemir
Emel Soysaldı
Yusuf Kale
Sumru Kavurt
Ahmet Yagmur Bas
Nihal Demirel
Publication date
01-08-2014
Publisher
Springer India
Published in
Indian Journal of Pediatrics / Issue 8/2014
Print ISSN: 0019-5456
Electronic ISSN: 0973-7693
DOI
https://doi.org/10.1007/s12098-013-1209-2

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