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Published in: Indian Journal of Otolaryngology and Head & Neck Surgery 2/2022

13-02-2021 | Amphotericin B | Original Article

Extra-Rhino Cerebral Manifestations of Mucormycosis in Head and Neck Region: An Insight

Authors: Disha Bansal, Apoorva Kumar Pandey, Aparna Bhardwaj, Chetan Bansal, Arvind Varma, Ajaz ul Haq, Sharad Harnnot

Published in: Indian Journal of Otolaryngology and Head & Neck Surgery | Special Issue 2/2022

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Abstract

Mucormycosis is a potentially life-threatening fungal infection with a high mortality rate. The difficulty and delay in diagnosis due to its rarity usually results in a poor prognosis. Most common site in head and neck region is the nose and paranasal sinuses. However there are other very unusual areas in head and neck region where mucormycosis is encountered. Knowledge of these unusual areas is must and can save a patient’s life. To elaborate and highlight the unusual areas in head and neck region where mucormycosis can mimic other common diseases. This retrospective study was done from May 2010 to May 2019 over a period of 9 years. All histopathologically confirmed cases of Head and Neck mucormycosis were evaluated and data analyzed. Total 35 cases of head neck mucormycosis were encountered from May 2010 to May 2019 over a period of 9 years. Out of which 30 cases (85.72%) were of rhino-orbito-cerebral mucormycosis and 5 cases (14.28%) were EXTRA rhino-orbito-cerebral mucormycosis in head neck region. Mucormycosis at such unusual sites can cause diagnostic dilemma for the treating doctor. Clinical knowledge with anticipation is a must for success in treatment of mucormycosis in unusual places in head neck region especially when normal looking diseases does not respond to usual treatment.
Literature
2.
go back to reference Desai V, Pratik P (2014) Mucormycosis Of Oral Mucosa: A Rare Case Report. Int J Pharm Chem Biol Sci 4(3):509–511 Desai V, Pratik P (2014) Mucormycosis Of Oral Mucosa: A Rare Case Report. Int J Pharm Chem Biol Sci 4(3):509–511
4.
go back to reference Joel B. Epstein, Steven B. Kupferman , Rachel Zabner, Ali Rejali, Martin L. Hopp, Michael Lill, Dimitrios Tzachanis (2016) Early diagnosis and successful management of oral mucormycosis in a hematopoietic stem cell transplant recipient: case report and literature review. 24(8):3343–3346 Joel B. Epstein, Steven B. Kupferman , Rachel Zabner, Ali Rejali, Martin L. Hopp, Michael Lill, Dimitrios Tzachanis (2016) Early diagnosis and successful management of oral mucormycosis in a hematopoietic stem cell transplant recipient: case report and literature review. 24(8):3343–3346
5.
go back to reference Sathish Kumar KN, Nishan N (2015) Mucormycosis of the temporal bone with facial nerve palsy: A rare case report. Indian J Otol 21:61–63CrossRef Sathish Kumar KN, Nishan N (2015) Mucormycosis of the temporal bone with facial nerve palsy: A rare case report. Indian J Otol 21:61–63CrossRef
6.
go back to reference Varghese R, Nair RM, Kavalakkat FJ (2014) Fungal otomastoiditis: A case series in immunocompetent Adults. Indian J Otolaryngol Head Neck Surg 66(1):110–113CrossRefPubMed Varghese R, Nair RM, Kavalakkat FJ (2014) Fungal otomastoiditis: A case series in immunocompetent Adults. Indian J Otolaryngol Head Neck Surg 66(1):110–113CrossRefPubMed
7.
go back to reference Hazarika P, Zachariah J, Victor J, John M, Devi C, Abraham P (2012) Mucormycosis of the Middle Ear: A Case Report with Review of Literature. Indian J Otolaryngol Head Neck Surg 64(1):90–94CrossRefPubMed Hazarika P, Zachariah J, Victor J, John M, Devi C, Abraham P (2012) Mucormycosis of the Middle Ear: A Case Report with Review of Literature. Indian J Otolaryngol Head Neck Surg 64(1):90–94CrossRefPubMed
8.
go back to reference McDermott NE, Barrett J, Hipp J (2010) Successful treatment of periodontal mucormycosis: Report of a case and literature review. Oral Surg Oral Med Oral Pathol Oral Radiol Endodont 109:e64–e69CrossRef McDermott NE, Barrett J, Hipp J (2010) Successful treatment of periodontal mucormycosis: Report of a case and literature review. Oral Surg Oral Med Oral Pathol Oral Radiol Endodont 109:e64–e69CrossRef
9.
go back to reference Bakathir AA (2006) Mucormycosis of the Jaw after dental extractions: two case reports. Sultan Qaboos Univ Med 6(2):77–82 Bakathir AA (2006) Mucormycosis of the Jaw after dental extractions: two case reports. Sultan Qaboos Univ Med 6(2):77–82
10.
go back to reference Bernal-Martínez L, Buitrago MJ, Castelli MV, Rodriguez-Tudela JL, Cuenca-Estrella M (2013) Development of a single tube multiplex real-time PCR to detect the most clinically relevant Mucormycetes species. Clin Microbiol Infect 19:E1-7CrossRefPubMed Bernal-Martínez L, Buitrago MJ, Castelli MV, Rodriguez-Tudela JL, Cuenca-Estrella M (2013) Development of a single tube multiplex real-time PCR to detect the most clinically relevant Mucormycetes species. Clin Microbiol Infect 19:E1-7CrossRefPubMed
Metadata
Title
Extra-Rhino Cerebral Manifestations of Mucormycosis in Head and Neck Region: An Insight
Authors
Disha Bansal
Apoorva Kumar Pandey
Aparna Bhardwaj
Chetan Bansal
Arvind Varma
Ajaz ul Haq
Sharad Harnnot
Publication date
13-02-2021
Publisher
Springer India
Published in
Indian Journal of Otolaryngology and Head & Neck Surgery / Issue Special Issue 2/2022
Print ISSN: 2231-3796
Electronic ISSN: 0973-7707
DOI
https://doi.org/10.1007/s12070-021-02440-z

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