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Published in: Indian Journal of Thoracic and Cardiovascular Surgery 3/2023

21-02-2023 | Angiography | Critical Appraisal of Trials

VEST III trial — should we support the vein grafts?

Author: Pradeep Narayan

Published in: Indian Journal of Thoracic and Cardiovascular Surgery | Issue 3/2023

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Abstract

VEST III trial is the largest randomized controlled trial to date to evaluate the role of external stents on late graft failure. In this study, an external stent was applied to vein grafts and compared with another unsupported vein graft in the same patient. The groups were compared for overall graft patency and intimal hyperplasia. Patent vein grafts were further assessed and graded based on the Fitzgibbon patency scale. This review discusses the strengths and weaknesses of the trial.
Literature
1.
go back to reference Taggart DP, Gavrilov Y, Krasopoulos G, Rajakaruna C, Zacharias J, De Silva R, et al. External stenting and disease progression in saphenous vein grafts two years after coronary artery bypass grafting: a multicenter randomized trial. J Thorac Cardiovasc Surg. 2022;164:1532-1541.e2.CrossRefPubMed Taggart DP, Gavrilov Y, Krasopoulos G, Rajakaruna C, Zacharias J, De Silva R, et al. External stenting and disease progression in saphenous vein grafts two years after coronary artery bypass grafting: a multicenter randomized trial. J Thorac Cardiovasc Surg. 2022;164:1532-1541.e2.CrossRefPubMed
2.
go back to reference FitzGibbon GM, Leach AJ, Keon WJ, Burton JR, Kafka HP. Coronary bypass graft fate. Angiographic study of 1,179 vein grafts early, one year, and five years after operation. J Thorac Cardiovasc Surg. 1986;91:773–8.CrossRefPubMed FitzGibbon GM, Leach AJ, Keon WJ, Burton JR, Kafka HP. Coronary bypass graft fate. Angiographic study of 1,179 vein grafts early, one year, and five years after operation. J Thorac Cardiovasc Surg. 1986;91:773–8.CrossRefPubMed
3.
go back to reference Taggart DP, Ben Gal Y, Lees B, Patel N, Webb C, Rehman SM, et al. A randomized trial of external stenting for saphenous vein grafts in coronary artery bypass grafting. Ann Thorac Surg. 2015;99:2039–45.CrossRefPubMed Taggart DP, Ben Gal Y, Lees B, Patel N, Webb C, Rehman SM, et al. A randomized trial of external stenting for saphenous vein grafts in coronary artery bypass grafting. Ann Thorac Surg. 2015;99:2039–45.CrossRefPubMed
4.
go back to reference Taggart DP, Amin S, Djordjevic J, Oikonomou EK, Thomas S, Kampoli A-M, et al. A prospective study of external stenting of saphenous vein grafts to the right coronary artery: the VEST II study. Eur J Cardio-Thorac Surg. 2017;51:952–8.CrossRef Taggart DP, Amin S, Djordjevic J, Oikonomou EK, Thomas S, Kampoli A-M, et al. A prospective study of external stenting of saphenous vein grafts to the right coronary artery: the VEST II study. Eur J Cardio-Thorac Surg. 2017;51:952–8.CrossRef
5.
go back to reference Taggart DP, Webb CM, Desouza A, Yadav R, Channon KM, De Robertis F, et al. Long-term performance of an external stent for saphenous vein grafts: the VEST IV trial. J Cardiothorac Surg. 2018;13:117.CrossRefPubMedPubMedCentral Taggart DP, Webb CM, Desouza A, Yadav R, Channon KM, De Robertis F, et al. Long-term performance of an external stent for saphenous vein grafts: the VEST IV trial. J Cardiothorac Surg. 2018;13:117.CrossRefPubMedPubMedCentral
6.
go back to reference Hage A, Voisine P, Erthal F, Larose É, Glineur D, Chow B, et al. Eight-year follow-up of the Clopidogrel After Surgery for Coronary Artery Disease (CASCADE) trial. J Thorac Cardiovasc Surg. 2018;155:212-222.e2.CrossRefPubMed Hage A, Voisine P, Erthal F, Larose É, Glineur D, Chow B, et al. Eight-year follow-up of the Clopidogrel After Surgery for Coronary Artery Disease (CASCADE) trial. J Thorac Cardiovasc Surg. 2018;155:212-222.e2.CrossRefPubMed
7.
go back to reference Nantsios A, Vo TX, Ruel M. Commentary: external stenting of saphenous vein grafts-reinVESTing to achieve best returns in coronary artery bypass grafting. J Thorac Cardiovasc Surg. 2022;164:1542–3.CrossRefPubMed Nantsios A, Vo TX, Ruel M. Commentary: external stenting of saphenous vein grafts-reinVESTing to achieve best returns in coronary artery bypass grafting. J Thorac Cardiovasc Surg. 2022;164:1542–3.CrossRefPubMed
8.
go back to reference Vervoort D, Malik A, Fremes SE. The evolving evidence base for coronary artery bypass grafting and arterial grafting in 2021: how to improve vein graft patency. JTCVS Tech. 2021;10:102–9.CrossRefPubMedPubMedCentral Vervoort D, Malik A, Fremes SE. The evolving evidence base for coronary artery bypass grafting and arterial grafting in 2021: how to improve vein graft patency. JTCVS Tech. 2021;10:102–9.CrossRefPubMedPubMedCentral
Metadata
Title
VEST III trial — should we support the vein grafts?
Author
Pradeep Narayan
Publication date
21-02-2023
Publisher
Springer Nature Singapore
Published in
Indian Journal of Thoracic and Cardiovascular Surgery / Issue 3/2023
Print ISSN: 0970-9134
Electronic ISSN: 0973-7723
DOI
https://doi.org/10.1007/s12055-023-01492-w

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