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01-12-2014 | Case Report

Metastatic Leiomyosarcoma to the Pancreas Presenting as a Massive Upper Gastrointestinal Hemorrhage

Authors: Christian Andrade, Jon Finan, Prasad Kulkarni

Published in: Journal of Gastrointestinal Cancer | Special Issue 1/2014

Excerpt

Leiomyosarcomas are rare, comprising only 0.1 % of all primary pancreatic malignancies [1]. They originate from smooth muscle and are most commonly found within the stomach and small intestine as well as in the large intestine, uterus, and retroperitoneum [2]. Leiomyosarcomas have a predilection for hematogenous spread with the liver and lungs being the most common sites of metastasis. Diagnosis requires immunohistochemical confirmation with positivity most commonly seen for smooth muscle actin (SMA), caldesmon, vimentin, and desmin. In a recent review, only 25 cases of solitary metastatic leiomyosarcomas were found in the literature [3]. …

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Title: Metastatic Leiomyosarcoma to the Pancreas Presenting as a Massive Upper Gastrointestinal Hemorrhage
Authors: Christian Andrade
Jon Finan
Prasad Kulkarni
Publication date: 01-12-2014
Publisher: Springer US
Published in: Journal of Gastrointestinal Cancer / Issue Special Issue 1/2014
Print ISSN: 1941-6628
Electronic ISSN: 1941-6636
DOI: https://doi.org/10.1007/s12029-014-9644-5

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