Skip to main content
Top
Published in: Neurocritical Care 1/2009

01-02-2009 | Practical Pearl

Cardiogenic Shock with Stunned Myocardium during Triple-H Therapy Treated with Intra-aortic Balloon Pump Counterpulsation

Authors: Fabio Silvio Taccone, Boris Lubicz, Michael Piagnerelli, Marc Van Nuffelen, Jean-Louis Vincent, Daniel De Backer

Published in: Neurocritical Care | Issue 1/2009

Login to get access

Abstract

Introduction

Excessive use of adrenergic agents may result in stunned myocardium.

Cases

We report the cases of two patients with subarachnoid hemorrhage (SAH) complicated by cardiogenic shock secondary to triple-H therapy for cerebral vasospasm. Both patients had normal cardiac function on admission and no signs of acute myocardial infarction at the onset of cardiogenic shock. Intra-aortic balloon pump (IABP) counterpulsation was used to maintain adequate cerebral perfusion while enabling the high doses of norepinephrine that were being administered to be reduced. Reversal of the myocardial dysfunction after vasopressors were discontinued supported a diagnosis of catecholamine-induced stunned myocardium.

Conclusion

IABP counterpulsation may be one therapeutic option for patients with vasospasm after SAH when high doses of vasopressors can induce severe myocardial dysfunction. However, this invasive device may not be sufficient to maintain adequate cerebral perfusion and fatal embolic events can complicate the clinical course.
Literature
1.
go back to reference Mayberg MR, Batjer HH, Dacey R, et al. Guidelines for the management of aneurysmal subarachnoid hemorrhage: a statement for health care professionals from a special writing group of the Stroke Council, American Heart Association. Circulation. 1994;90:2592–605.PubMed Mayberg MR, Batjer HH, Dacey R, et al. Guidelines for the management of aneurysmal subarachnoid hemorrhage: a statement for health care professionals from a special writing group of the Stroke Council, American Heart Association. Circulation. 1994;90:2592–605.PubMed
7.
go back to reference Bulsara KR, McGirt MJ, Liao L, et al. Use of the peak troponin value to differentiate myocardial infarction from reversible neurogenic left ventricular dysfunction associated with aneurysmal subarachnoid hemorrhage. J Neurosurg. 2003;98:524–8.PubMed Bulsara KR, McGirt MJ, Liao L, et al. Use of the peak troponin value to differentiate myocardial infarction from reversible neurogenic left ventricular dysfunction associated with aneurysmal subarachnoid hemorrhage. J Neurosurg. 2003;98:524–8.PubMed
9.
go back to reference Kono T, Morita H, Kuroiwa T, Onaka H, Takatsuka H, Fujiwara A. Left ventricular wall motion abnormalities in patients with subarachnoid hemorrhage: neurogenic stunned myocardium. J Am Coll Cardiol. 1994;24:636–40.PubMed Kono T, Morita H, Kuroiwa T, Onaka H, Takatsuka H, Fujiwara A. Left ventricular wall motion abnormalities in patients with subarachnoid hemorrhage: neurogenic stunned myocardium. J Am Coll Cardiol. 1994;24:636–40.PubMed
11.
go back to reference Tsuchihashi K, Ueshima K, Uchida T, et al. Transient left ventricular apical ballooning without coronary artery stenosis: a novel heart syndrome mimicking acute myocardial infarction. Angina Pectoris-Myocardial Infarction Investigations in Japan. J Am Coll Cardiol. 2001;38:11–8. doi:10.1016/S0735-1097(01)01316-X.CrossRefPubMed Tsuchihashi K, Ueshima K, Uchida T, et al. Transient left ventricular apical ballooning without coronary artery stenosis: a novel heart syndrome mimicking acute myocardial infarction. Angina Pectoris-Myocardial Infarction Investigations in Japan. J Am Coll Cardiol. 2001;38:11–8. doi:10.​1016/​S0735-1097(01)01316-X.CrossRefPubMed
13.
go back to reference Doshi R, Neil-Dwyer G. A clinicopathological study of patients following a subarachnoid hemorrhage. J Neurosurg. 1980;52:295–301.PubMed Doshi R, Neil-Dwyer G. A clinicopathological study of patients following a subarachnoid hemorrhage. J Neurosurg. 1980;52:295–301.PubMed
14.
go back to reference Sato K, Masuda T, Kikuno T, et al. Left ventricular asynergy and myocardial necrosis accompanied by subarachnoid hemorrhage: contribution of neurogenic pulmonary edema. J Cardiol. 1990;20:359–67.PubMed Sato K, Masuda T, Kikuno T, et al. Left ventricular asynergy and myocardial necrosis accompanied by subarachnoid hemorrhage: contribution of neurogenic pulmonary edema. J Cardiol. 1990;20:359–67.PubMed
15.
go back to reference Bolli R. Mechanism of myocardial “stunning”. Circulation. 1990;82:723–38.PubMed Bolli R. Mechanism of myocardial “stunning”. Circulation. 1990;82:723–38.PubMed
16.
go back to reference Bolli R, Marban E. Molecular and cellular mechanisms of myocardial stunning. Physiol Rev. 1999;79:609–34.PubMed Bolli R, Marban E. Molecular and cellular mechanisms of myocardial stunning. Physiol Rev. 1999;79:609–34.PubMed
17.
go back to reference Jain R, Deveikis J, Thompson BG. Management of patients with stunned myocardium associated with subarachnoid hemorrhage. AJNR Am J Neuroradiol. 2004;25:126–9.PubMed Jain R, Deveikis J, Thompson BG. Management of patients with stunned myocardium associated with subarachnoid hemorrhage. AJNR Am J Neuroradiol. 2004;25:126–9.PubMed
19.
go back to reference Chang PC, Lee SH, Hung HF, Kaun P, Cheng JJ. Transient ST elevation and left ventricular asynergy associated with normal coronary artery and Tc-99m PYP Myocardial Infarct Scan in subarachnoid hemorrhage. Int J Cardiol. 1998;63:189–92. doi:10.1016/S0167-5273(97)00293-3.CrossRefPubMed Chang PC, Lee SH, Hung HF, Kaun P, Cheng JJ. Transient ST elevation and left ventricular asynergy associated with normal coronary artery and Tc-99m PYP Myocardial Infarct Scan in subarachnoid hemorrhage. Int J Cardiol. 1998;63:189–92. doi:10.​1016/​S0167-5273(97)00293-3.CrossRefPubMed
20.
go back to reference Pfister D, Strebel SP, Steiner LA. Effects of catecholamines on cerebral blood vessels in patients with traumatic brain injury. Eur J Anaesthesiol Suppl. 2008;42:98–103.PubMed Pfister D, Strebel SP, Steiner LA. Effects of catecholamines on cerebral blood vessels in patients with traumatic brain injury. Eur J Anaesthesiol Suppl. 2008;42:98–103.PubMed
21.
go back to reference Levy ML, Rabb CH, Zelman V, Giannotta SL. Cardiac performance enhancement from dobutamine in patients refractory to hypervolemic therapy for cerebral vasospasm. J Neurosurg. 1993;79:494–9.PubMed Levy ML, Rabb CH, Zelman V, Giannotta SL. Cardiac performance enhancement from dobutamine in patients refractory to hypervolemic therapy for cerebral vasospasm. J Neurosurg. 1993;79:494–9.PubMed
23.
go back to reference Kassell NF, Helm G, Simmons N, Phillips CD, Cail WS. Treatment of cerebral vasospasm with intra-arterial papaverine. J Neurosurg. 1992;77:848–52.PubMedCrossRef Kassell NF, Helm G, Simmons N, Phillips CD, Cail WS. Treatment of cerebral vasospasm with intra-arterial papaverine. J Neurosurg. 1992;77:848–52.PubMedCrossRef
24.
go back to reference Higashida RT, Halbach VV, Dowd CF, Dormandy B, Bell J, Hieshima GB. Intravascular balloon dilatation therapy for intracranial arterial vasospasm: patient selection, technique, and clinical results. Neurosurg Rev. 1992;15:89–95. doi:10.1007/BF00313501.CrossRefPubMed Higashida RT, Halbach VV, Dowd CF, Dormandy B, Bell J, Hieshima GB. Intravascular balloon dilatation therapy for intracranial arterial vasospasm: patient selection, technique, and clinical results. Neurosurg Rev. 1992;15:89–95. doi:10.​1007/​BF00313501.CrossRefPubMed
25.
28.
go back to reference Vijayalakshmi K, Kunadian B, Whittaker VJ, et al. Intra-aortic counterpulsation does not improve coronary flow early after PCI in a high-risk group of patients: observations from a randomized trial to explore its mode of action. J Invasive Cardiol. 2007;19:339–46.PubMed Vijayalakshmi K, Kunadian B, Whittaker VJ, et al. Intra-aortic counterpulsation does not improve coronary flow early after PCI in a high-risk group of patients: observations from a randomized trial to explore its mode of action. J Invasive Cardiol. 2007;19:339–46.PubMed
31.
go back to reference Simeone FA, Laurent JP, Trepper PJ, Brown DJ, Cotter J. Experimental augmentation of cerebral blood flow by intermittent aortic occlusion. J Neurosurg. 1972;36:700–13.PubMed Simeone FA, Laurent JP, Trepper PJ, Brown DJ, Cotter J. Experimental augmentation of cerebral blood flow by intermittent aortic occlusion. J Neurosurg. 1972;36:700–13.PubMed
32.
go back to reference Nussbaum ES, Heros RC, Solien EE, Madison MT, Sebring LA, Latchaw RE. Intra-aortic balloon counterpulsation augments cerebral blood flow in a canine model of subarachnoid hemorrhage-induced cerebral vasospasm. Neurosurgery. 1995;36:879–84. doi:10.1097/00006123-199504000-00047.CrossRefPubMed Nussbaum ES, Heros RC, Solien EE, Madison MT, Sebring LA, Latchaw RE. Intra-aortic balloon counterpulsation augments cerebral blood flow in a canine model of subarachnoid hemorrhage-induced cerebral vasospasm. Neurosurgery. 1995;36:879–84. doi:10.​1097/​00006123-199504000-00047.CrossRefPubMed
33.
go back to reference Tranmer BI, Gross CE, Kindt GW, Adey GR. Pulsatile versus nonpulsatile blood flow in the treatment of acute cerebral ischemia. Neurosurgery. 1986;19:724–31.PubMedCrossRef Tranmer BI, Gross CE, Kindt GW, Adey GR. Pulsatile versus nonpulsatile blood flow in the treatment of acute cerebral ischemia. Neurosurgery. 1986;19:724–31.PubMedCrossRef
34.
35.
go back to reference Gee W, Smith RL, Perline RK, Gallagher HS. Assessment of intra-aortic balloon pumping by ocular pneumoplethysmography. Am Surg. 1986;52:489–91.PubMed Gee W, Smith RL, Perline RK, Gallagher HS. Assessment of intra-aortic balloon pumping by ocular pneumoplethysmography. Am Surg. 1986;52:489–91.PubMed
37.
go back to reference Brass LM. Reversed intracranial blood flow in patients with an intra-aortic balloon pump. Stroke. 1990;21:484–7.PubMed Brass LM. Reversed intracranial blood flow in patients with an intra-aortic balloon pump. Stroke. 1990;21:484–7.PubMed
38.
39.
go back to reference Apostolides PJ, Greene KA, Zabramski JM, Fitzgerald JW, Spetzler RF. Intra-aortic balloon pump counterpulsation in the management of concomitant cerebral vasospasm and cardiac failure after subarachnoid hemorrhage: technical case report. Neurosurgery. 1996;38:1056–9. doi:10.1097/00006123-199605000-00042.CrossRefPubMed Apostolides PJ, Greene KA, Zabramski JM, Fitzgerald JW, Spetzler RF. Intra-aortic balloon pump counterpulsation in the management of concomitant cerebral vasospasm and cardiac failure after subarachnoid hemorrhage: technical case report. Neurosurgery. 1996;38:1056–9. doi:10.​1097/​00006123-199605000-00042.CrossRefPubMed
Metadata
Title
Cardiogenic Shock with Stunned Myocardium during Triple-H Therapy Treated with Intra-aortic Balloon Pump Counterpulsation
Authors
Fabio Silvio Taccone
Boris Lubicz
Michael Piagnerelli
Marc Van Nuffelen
Jean-Louis Vincent
Daniel De Backer
Publication date
01-02-2009
Publisher
Humana Press Inc
Published in
Neurocritical Care / Issue 1/2009
Print ISSN: 1541-6933
Electronic ISSN: 1556-0961
DOI
https://doi.org/10.1007/s12028-008-9135-2

Other articles of this Issue 1/2009

Neurocritical Care 1/2009 Go to the issue