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Published in: Neurocritical Care 1/2008

01-08-2008 | Original Paper

Evoked Potentials in Acute Ischemic Stroke within the First 24 h: Possible Predictor of a Malignant Course

Authors: Lothar Burghaus, Wei-Chi Liu, Christian Dohmen, Bert Bosche, Walter F. Haupt

Published in: Neurocritical Care | Issue 1/2008

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Abstract

Objective

In patients with large middle cerebral artery (MCA) infarction, space-occupying brain edema may lead to a malignant course with up to 80% mortality, under conservative treatment. As interventional treatment strategies must be started before the deterioration occurs, predictors of a malignant course are necessary.

Material and Methods

This study reports on the results of evoked potentials (brainstem auditory evoked potentials [BAEP] and median-nerve somatosensory evoked potentials [SEP]) within 24 h after onset of stroke in 30 patients suffering a large MCA infarct (14 patients with a malignant and 16 with a non-malignant course).

Results

Our findings indicate that pathological BAEP indicate a malignant course (P < 0.05).

Conclusion

This study shows that in patients suffering from large MCA infarction early assessment of EP within 24 h after onset of stroke may deliver useful information to select those patients who develop malignant edema.
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Metadata
Title
Evoked Potentials in Acute Ischemic Stroke within the First 24 h: Possible Predictor of a Malignant Course
Authors
Lothar Burghaus
Wei-Chi Liu
Christian Dohmen
Bert Bosche
Walter F. Haupt
Publication date
01-08-2008
Publisher
Humana Press Inc
Published in
Neurocritical Care / Issue 1/2008
Print ISSN: 1541-6933
Electronic ISSN: 1556-0961
DOI
https://doi.org/10.1007/s12028-007-9025-z

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