Metabolic syndrome associated with hyperprolactinemia: A new indication for dopamine agonist treatment?

Excerpt

In this issue of Endocrine, Inancli and co-authors present the manuscript “Effect of cabergoline on insulin sensitivity, inflammation, and carotid intima media thickness in patients with prolactinoma” [1]. They found that cabergoline treatment was associated with significant improvements in body mass index; total, HDL, and LDL-cholesterol levels and insulin sensitivity, also with a decrease in pro-inflammatory markers and carotid intima media thickness. Only the decrease in total and LDL-cholesterol showed a positive correlation with PRL levels. They concluded that patients with prolactinoma may have a higher vascular risk and cabergoline treatment may be associated with better endothelial function [1]. …