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Clinical Orthopaedics and Related Research®

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01-03-2014 | Clinical Research

Does Obesity Affect the Surgical Outcome and Complication Rates of Spinal Surgery? A Meta-analysis

Authors: Jin Jiang, MD, Yuanjun Teng, MD, Zhenzhen Fan, MD, Shahidur Khan, MD, Yayi Xia, MD, PhD

Published in: Clinical Orthopaedics and Related Research® | Issue 3/2014

Abstract

Background

As obesity becomes more prevalent, it becomes more common among patients considering orthopaedic surgery, including spinal surgery. However, there is some controversy regarding whether obesity is associated with complications, failed reconstructions, or reoperations after spinal surgery.

Questions/purposes

We wished to determine, in patients undergoing spine surgery, whether obesity is associated with (1) surgical site infection, (2) mortality and the need for revision surgery after spinal surgery, and (3) increased surgical time and blood loss.

Methods

A systematic literature search was performed to collect comparative or controlled studies that evaluated the influence of obesity on the surgical and postoperative outcomes of spinal surgery. Two reviewers independently selected trials, extracted data, and assessed the methodologic quality and quality of evidence. Pooled odds ratios (OR) and mean differences (MD) with 95% CIs were calculated using the fixed-effects model or random-effects model. Data were analyzed using RevMan 5.1. MOOSE criteria were used to ensure this project’s validity. Thirty-two studies involving 97,326 patients eventually were included.

Results

Surgical site infection (OR, 2.33; 95% CI, 1.94–2.79), venous thromboembolism (OR, 3.15; 95% CI, 1.92–5.17), mortality (OR, 2.6; 95% CI, 1.50–4.49), revision rate (OR, 1.43; 95% CI, 1.05–1.93) operating time (OR, 14.55; 95% CI, 10.03–19.07), and blood loss (MD, 28.89; 95% CI, 14.20–43.58), were all significantly increased in the obese group.

Conclusion

Obesity seemed to be associated with higher risk of surgical site infection and venous thromboembolism, more blood loss, and longer surgical time. Future prospective studies are needed to confirm the relationship between obesity and the outcome of spinal surgery.

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Title: Does Obesity Affect the Surgical Outcome and Complication Rates of Spinal Surgery? A Meta-analysis
Authors: Jin Jiang, MD
Yuanjun Teng, MD
Zhenzhen Fan, MD
Shahidur Khan, MD
Yayi Xia, MD, PhD
Publication date: 01-03-2014
Publisher: Springer US
Published in: Clinical Orthopaedics and Related Research® / Issue 3/2014
Print ISSN: 0009-921X
Electronic ISSN: 1528-1132
DOI: https://doi.org/10.1007/s11999-013-3346-3

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Does Obesity Affect the Surgical Outcome and Complication Rates of Spinal Surgery? A Meta-analysis

Abstract

Background

Questions/purposes

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Questions/purposes

Methods

Results

Conclusion

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